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In recent years, however, there has been an increasing number of reported infections, some of them fatal, caused by\n            <jats:named-content content-type=\"genus-species\">C. gilardii<\/jats:named-content>\n            . These infections are hard to treat because this bacterium is naturally resistant to many antibiotics, including last-resort antibiotics, such as carbapenems. Moreover, this bacterium often becomes resistant to additional antibiotics during therapy. However, little is known about\n            <jats:named-content content-type=\"genus-species\">C. gilardii<\/jats:named-content>\n            and its antibiotic resistance mechanisms. The significance of our research is in providing, for the first time, whole-genome information about the natural antibiotic resistance genes found in this bacterium and their conservation among different\n            <jats:named-content content-type=\"genus-species\">C. gilardii<\/jats:named-content>\n            strains. 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