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Interkingdom polymicrobial associations modify fungal pathogenicity and are believed to increase microbial resistance to innate immunity. However, it is not known how these interactions alter fungal survival during phagocytic killing. We demonstrated that secreted molecules of\n                    <jats:named-content content-type=\"genus-species\">S. gordonii<\/jats:named-content>\n                    and\n                    <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n                    alter\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    survival within the phagosome of macrophages and alter fungal pathogenic phenotypes, including filamentation and microcolony formation. Moreover, we provide evidence for a dual interaction between\n                    <jats:named-content content-type=\"genus-species\">S. gordonii<\/jats:named-content>\n                    and\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    such that\n                    <jats:named-content content-type=\"genus-species\">S. gordonii<\/jats:named-content>\n                    signaling peptides can promote\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    commensalism by decreasing microcolony attachment while increasing invasion in epithelial cells. Our results identify bacterial diffusible factors as an attractive target to modify virulence of\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    in polymicrobial infections.\n                  <\/jats:p>","DOI":"10.1128\/msphere.00689-20","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T09:40:42Z","timestamp":1596534042000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["Bacteria Modify\n                    <i>Candida albicans<\/i>\n                    Hypha Formation, Microcolony Properties, and Survival within Macrophages"],"prefix":"10.1128","volume":"5","author":[{"given":"Ornella","family":"Salvatori","sequence":"first","affiliation":[{"name":"Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, New York, 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