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It is critical to understand the mechanisms and host contexts under which opportunistic pathogens become virulent. In this work, we present a novel assay to quickly and quantitatively measure pathogen virulence in healthy and immunocompromised nematode hosts. We found that\n                    <jats:italic>Candida<\/jats:italic>\n                    species, one of the most prominent fungal opportunistic pathogens of humans, decrease host fitness by reducing survival and impacting host reproduction. Most importantly, by measuring virulence in hosts that have intact or compromised immune function, we can reveal the pathogenic potential of opportunistic fungal pathogens.\n                  <\/jats:p>","DOI":"10.1128\/msphere.00697-18","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T06:39:16Z","timestamp":1554791956000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["A Novel Virulence Phenotype Rapidly Assesses\n                    <i>Candida<\/i>\n                    Fungal Pathogenesis in Healthy and Immunocompromised\n                    <i>Caenorhabditis elegans<\/i>\n                    Hosts"],"prefix":"10.1128","volume":"4","author":[{"given":"Dorian J.","family":"Feistel","sequence":"first","affiliation":[{"name":"Department of Biology, Emory University, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rema","family":"Elmostafa","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"McKenna","family":"Penley","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levi","family":"Morran","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4237-6981","authenticated-orcid":false,"given":"Meleah A.","family":"Hickman","sequence":"additional","affiliation":[{"name":"Department of Biology, Emory University, Atlanta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3684"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.26"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/520192"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004404"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/363764"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/22.Supplement_2.S89"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199705000-00002"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/323812"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.10.4468-4472.2004"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.9.3254-3259.2001"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.4.1519-1527.2004"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens3030549"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/0471142735.im1906s105"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof3040060"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2017.10.030"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2018.02.026"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.10.008"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00163-09"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.174623.114"},{"key":"e_1_3_2_21_2","first-page":"403","article-title":"Models of Caenorhabditis elegans infection by bacterial and fungal pathogens","volume":"415","author":"Powell JR","year":"2008","unstructured":"Powell JR, Ausubel FM. 2008. 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