{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T01:48:05Z","timestamp":1779241685688,"version":"3.51.4"},"reference-count":73,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R21AI133445"],"award-info":[{"award-number":["R21AI133445"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["T32HL134640"],"award-info":[{"award-number":["T32HL134640"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL102371"],"award-info":[{"award-number":["R01HL102371"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R21AI144507"],"award-info":[{"award-number":["R21AI144507"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2022,2,23]]},"abstract":"<jats:p>Chronic bacterial respiratory infections are a significant problem for smoke-exposed individuals, especially those with chronic obstructive pulmonary disease (COPD). These infections often persist despite antibiotic use.<\/jats:p>","DOI":"10.1128\/msphere.00847-21","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T12:13:00Z","timestamp":1642594380000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["Nontypeable Haemophilus influenzae Redox Recycling of Protein Thiols Promotes Resistance to Oxidative Killing and Bacterial Survival in Biofilms in a Smoke-Related Infection Model"],"prefix":"10.1128","volume":"7","author":[{"given":"Benjamin C.","family":"Hunt","sequence":"first","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"},{"name":"Gregory Fleming James Center for Cystic Fibrosis Research, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Xu","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Gaggar","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"},{"name":"Gregory Fleming James Center for Cystic Fibrosis Research, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4063-940X","authenticated-orcid":true,"given":"W. Edward","family":"Swords","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"},{"name":"Gregory Fleming James Center for Cystic Fibrosis Research, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4137\/TUI.S15628"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.20.2206"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2017.93"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2019.08.014"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.12351"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2007.06.004"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/1040841X.2017.1329274"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsim.2004.12.008"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftx042"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016488409130971"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1972.tb00181.x"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017035"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-79680-6"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2012.00097"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftw112"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200509-1459OC"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-2-7"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/1040841X.2019.1660616"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.2.202"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2009.01323.x"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/322972"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0809.020063"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2019.06.002"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/apm.12099"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.12.011"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1159\/000205937"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.4MIR0220-574RR"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00964-19"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2012.00040"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3032"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1080\/08927014.2015.1134515"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10541-005-0248-3"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.18.5555-5562.2003"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.5.1572-1581.2003"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005198107"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M300157200"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.02390-14"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13416"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00405.2017"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200808-1306OC"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01040-06"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2014.11.013"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1039\/c1cc12127h"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/0471140856.tx1702s38"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi992025k"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.44.101802.121735"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00200-2020"},{"key":"e_1_3_2_49_2","first-page":"45","article-title":"Observation of viable nontypeable Haemophilus influenzae bacteria within neutrophil extracellular traps in clinical samples from chronic otitis media","volume":"3","author":"King L","year":"2013","unstructured":"King L, Pang B, Perez AC, Reimche JL, Kirse DJ, Whigham AS, Evans AK, Swords WE. 2013. Observation of viable nontypeable Haemophilus influenzae bacteria within neutrophil extracellular traps in clinical samples from chronic otitis media. Otolaryngology 3:45.","journal-title":"Otolaryngology"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00660-10"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01935-06"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05864.x"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.3.1828-1836.2006"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.1.106-113.2004"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00532-07"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01691-06"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.6.3210-3218.2005"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00320-09"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07831.x"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00506-18"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2012.00058"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2012.00058"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0044730"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01716-07"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.13.3625"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00439.2007"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00013.2009"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00067204"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.90382.2008"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.3109\/08958378.2014.917346"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2015.03.029"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-020-00817-4"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.134.3.1141-1156.1978"}],"container-title":["mSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/msphere.00847-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/msphere.00847-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T23:47:24Z","timestamp":1646696844000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/msphere.00847-21"}},"subtitle":[],"editor":[{"given":"Sarah E. F.","family":"D'Orazio","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,2,23]]},"references-count":73,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2,23]]}},"alternative-id":["10.1128\/msphere.00847-21"],"URL":"https:\/\/doi.org\/10.1128\/msphere.00847-21","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.08.25.457736","asserted-by":"object"}]},"ISSN":["2379-5042"],"issn-type":[{"value":"2379-5042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,23]]},"assertion":[{"value":"2021-10-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00847-21"}}