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These integrated phage elements have previously been implicated in horizontal gene transfer (HGT) largely through their ability to carry out transduction (generalized or specialized). Here, we show that prophage-encoded viral particles promote neighbor predation leading to enhanced HGT by natural transformation in the waterborne pathogen\n                    <jats:named-content content-type=\"genus-species\">Vibrio cholerae<\/jats:named-content>\n                    . Our findings contribute to a comprehensive understanding of the dynamic forces involved in prophage maintenance which ultimately drive the evolution of naturally competent bacteria in their natural environment.\n                  <\/jats:p>","DOI":"10.1128\/msphere.00975-20","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T08:49:20Z","timestamp":1604998160000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":31,"title":["Prophage-Dependent Neighbor Predation Fosters Horizontal Gene Transfer by Natural Transformation"],"prefix":"10.1128","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3653-7160","authenticated-orcid":false,"given":"Roberto C.","family":"Molina-Quiroz","sequence":"first","affiliation":[{"name":"Centro de Estudios Cient\u00edficos, Valdivia, Los Rios, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Triana 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