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Although it can usually be cured by antibiotics, the recurrence rate is very high, and some women do not respond to antibiotic therapy. The reasons for that are not known. Therefore, we undertook a study to detect the activity of the complete microbiota in the vaginal fluid of women who responded to antibiotic therapy and compared it to the activity of the microbiota in women who did not respond. We found that one of the most important pathogens in bacterial vaginosis,\n                    <jats:named-content content-type=\"genus-species\">Gardnerella vaginalis<\/jats:named-content>\n                    , has activated genes that can repair the DNA damage caused by the antibiotic in those women that do not respond to therapy. Suppressing these genes might be a possibility to improve the antibiotic therapy of bacterial vaginosis.\n                  <\/jats:p>","DOI":"10.1128\/mspheredirect.00262-18","type":"journal-article","created":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T06:18:56Z","timestamp":1531721936000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":75,"title":["Metatranscriptome Analysis of the Vaginal Microbiota Reveals Potential Mechanisms for Protection against Metronidazole in Bacterial Vaginosis"],"prefix":"10.1128","volume":"3","author":[{"given":"Zhi-Luo","family":"Deng","sequence":"first","affiliation":[{"name":"Research Group Microbial Communication, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Gottschick","sequence":"additional","affiliation":[{"name":"Research Group Microbial Communication, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabin","family":"Bhuju","sequence":"additional","affiliation":[{"name":"Genome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarissa","family":"Masur","sequence":"additional","affiliation":[{"name":"Dr. August Wolff GmbH &amp; Co. 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