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Mobile elements can trigger the diversification of lineages; therefore, characterizing the extent of genomic variation in a large collection of strains is critical for a complete understanding of the diversity and evolution of the species. Here, we sequenced a large collection of\n            <jats:named-content content-type=\"genus-species\">B.\u00a0anthracis<\/jats:named-content>\n            strains (&gt;400) that were recovered from human, animal, and environmental sources around the world. Our results confirmed the remarkable stability of gene content and synteny of the anthrax plasmids and revealed no signal of plasmid exchange between\n            <jats:named-content content-type=\"genus-species\">B.\u00a0anthracis<\/jats:named-content>\n            and pathogenic\n            <jats:named-content content-type=\"genus-species\">B.\u00a0cereus<\/jats:named-content>\n            isolates but rather predominantly vertical descent. These findings advance our understanding of the biology and pathogenomic evolution of\n            <jats:named-content content-type=\"genus-species\">B.\u00a0anthracis<\/jats:named-content>\n            and its plasmids.\n          <\/jats:p>","DOI":"10.1128\/msystems.00065-18","type":"journal-article","created":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T08:22:52Z","timestamp":1534753372000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":46,"title":["Genomic Characterization and Copy Number Variation of\n            <i>Bacillus anthracis<\/i>\n            Plasmids pXO1 and pXO2 in a Historical Collection of 412 Strains"],"prefix":"10.1128","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0684-8179","authenticated-orcid":false,"given":"Angela","family":"Pena-Gonzalez","sequence":"first","affiliation":[{"name":"School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7603-3093","authenticated-orcid":false,"given":"Luis M.","family":"Rodriguez-R","sequence":"additional","affiliation":[{"name":"School of Civil &amp; Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung K.","family":"Marston","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay E.","family":"Gee","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A.","family":"Gulvik","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cari B.","family":"Kolton","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Saile","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Frace","sequence":"additional","affiliation":[{"name":"Biotechnology Core Facility Branch, Division of Scientific Resources, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex R.","family":"Hoffmaster","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos T.","family":"Konstantinidis","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA"},{"name":"School of Civil &amp; 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