{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:28:39Z","timestamp":1790227719615,"version":"4.1.0"},"reference-count":60,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100000265","name":"UKRI | Medical Research Council","doi-asserted-by":"publisher","award":["MR\/N013638\/1"],"award-info":[{"award-number":["MR\/N013638\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UKRI | Medical Research Council","doi-asserted-by":"publisher","award":["MR\/P028322\/1"],"award-info":[{"award-number":["MR\/P028322\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UKRI | Medical Research Council","doi-asserted-by":"publisher","award":["MR\/P014658\/1"],"award-info":[{"award-number":["MR\/P014658\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSystems"],"published-print":{"date-parts":[[2022,4,26]]},"abstract":"<jats:p>Bacteriophage (phage), viruses that can infect and kill bacteria, are being investigated through phage therapy as a potential solution to the threat of antimicrobial resistance (AMR). In reality, however, phage are also natural drivers of bacterial evolution by transduction when they accidentally carry nonphage DNA between bacteria.<\/jats:p>","DOI":"10.1128\/msystems.00135-22","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T13:34:38Z","timestamp":1647869678000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":36,"title":["Growth-Dependent Predation and Generalized Transduction of Antimicrobial Resistance by Bacteriophage"],"prefix":"10.1128","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4761-001X","authenticated-orcid":true,"given":"Quentin J.","family":"Leclerc","sequence":"first","affiliation":[{"name":"Centre for Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology &amp; Population Health, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"},{"name":"Antimicrobial Resistance Centre, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5557-2899","authenticated-orcid":true,"given":"Jacob","family":"Wildfire","sequence":"additional","affiliation":[{"name":"Antimicrobial Resistance Centre, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"},{"name":"Institute for Infection &amp; Immunity, St. George\u2019s University of London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0873-4565","authenticated-orcid":true,"given":"Arya","family":"Gupta","sequence":"additional","affiliation":[{"name":"Institute for Infection &amp; Immunity, St. George\u2019s University of London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5219-1625","authenticated-orcid":true,"given":"Jodi A.","family":"Lindsay","sequence":"additional","affiliation":[{"name":"Institute for Infection &amp; Immunity, St. George\u2019s University of London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7263-9896","authenticated-orcid":true,"given":"Gwenan M.","family":"Knight","sequence":"additional","affiliation":[{"name":"Centre for Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology &amp; Population Health, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"},{"name":"Antimicrobial Resistance Centre, London School of Hygiene &amp; Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4161\/bact.1.1.14942"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00173"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41396-018-0049-5"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evu214"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2017.05.011"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.10.010"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70318-9"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/153567601001500106"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-014-1655-7"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/ph14030199"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/1040841X.2019.1691973"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2019.0260"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro822"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3109\/1040841X.2015.1114466"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.2307\/2406076"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1086\/283134"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5193(03)00262-5"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/285929"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0102507"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-137-3-661"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-143-1-179"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002480000050"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/mbo3.558"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2001.1945"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00446-14"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fiaa100"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007888"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30605-4"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2013.11.010"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-020-01891-8"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-019-0634-z"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-7343-9_1"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.08.036"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aat5867"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00537-12"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.76.11.5557-5564.2002"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-59635-7"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9868.00353"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.109.1.285-291.1972"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2008007118"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1314114111"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70036-7"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv119"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.58.11.3721-3729.1992"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-57129-0_6"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSystems.00756-19"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.06780-11"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.98.2.519-527.1969"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1974.tb41481.x"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2013.10.009"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2009.10.001"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsle\/fnw211"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.64.8.2780-2787.1998"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00223-21"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1057\/s41599-020-0478-4"},{"key":"e_1_3_2_57_2","volume-title":"R: a language and environment for statistical computing.","author":"R Core Team","year":"2020","unstructured":"R Core Team. 2020. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria."},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/0147-619X(83)90039-2"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01862-08"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.6966"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1214\/ss\/1177011136"}],"updated-by":[{"DOI":"10.1128\/msystems.00974-22","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000}}],"container-title":["mSystems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/msystems.00135-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/msystems.00135-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T13:07:19Z","timestamp":1650978439000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/msystems.00135-22"}},"subtitle":[],"editor":[{"given":"Jack A.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,4,26]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4,26]]}},"alternative-id":["10.1128\/msystems.00135-22"],"URL":"https:\/\/doi.org\/10.1128\/msystems.00135-22","relation":{"correction":[{"id-type":"doi","id":"10.1128\/msystems.00974-22","asserted-by":"object"}]},"ISSN":["2379-5077"],"issn-type":[{"value":"2379-5077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,26]]},"assertion":[{"value":"2022-02-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00135-22"}}