{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:16:01Z","timestamp":1790799361642,"version":"4.1.0"},"reference-count":64,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T00:00:00Z","timestamp":1640044800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T00:00:00Z","timestamp":1640044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100012236","name":"Alberta Agriculture and Forestry","doi-asserted-by":"publisher","award":["2018R009R"],"award-info":[{"award-number":["2018R009R"]}],"id":[{"id":"10.13039\/100012236","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSystems"],"published-print":{"date-parts":[[2021,12,21]]},"abstract":"<jats:p>Piglets are abruptly separated from their sow at weaning and are quickly transitioned from sow\u2019s milk to a plant-based diet. This is the most important period in commercial swine production, yet the effect of weaning age on the long-term development of the pig gut microbiome is largely unknown.<\/jats:p>","DOI":"10.1128\/msystems.00682-21","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T09:30:23Z","timestamp":1637659823000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":77,"title":["Weaning Age and Its Effect on the Development of the Swine Gut Microbiome and Resistome"],"prefix":"10.1128","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5306-3732","authenticated-orcid":true,"given":"Devin B.","family":"Holman","sequence":"first","affiliation":[{"name":"Lacombe Research and Development Centre, Agriculture and Agri-Food Canada, Lacombe, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine E.","family":"Gzyl","sequence":"additional","affiliation":[{"name":"Lacombe Research and Development Centre, Agriculture and Agri-Food Canada, Lacombe, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy T.","family":"Mou","sequence":"additional","affiliation":[{"name":"USDA, ARS, National Animal Disease Center, Ames, Iowa, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather K.","family":"Allen","sequence":"additional","affiliation":[{"name":"USDA, ARS, National Animal Disease Center, Ames, Iowa, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665107005484"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/2049-1891-4-19"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1079\/ahr2005105"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.54846\/jshap\/542","article-title":"Effect of weaning age on nursery pig and sow reproductive performance","volume":"16","author":"Smith AL","year":"2008","unstructured":"Smith AL, Stalder KJ, Serenius TV, Baas TJ, Mabry JW. 2008. Effect of weaning age on nursery pig and sow reproductive performance. J Swine Health Prod 16:131\u2013137.","journal-title":"J Swine Health Prod"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21295-0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/giaa051"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-015-0091-8"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6941.12419"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1758-2229.12285"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/sky109"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.01.016"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028742"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2014.07.028"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2017.05.004"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s42523-020-0020-4"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-015-5142-0"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.64778-0"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19929-w"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.002738"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.007641-0"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00589-13"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.112.169672"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00979"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2015-9081"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1079\/bjn19970072"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2020.12.022"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00032"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01416"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-015-0400-1"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/tas\/txaa052"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2014.03.008"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-018-9511-y"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSystems.00004-17"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-23025-x"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2016-10966"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.6b00497"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.5b05384"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf9044205"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03863.x"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.01.024"},{"key":"e_1_3_2_42_2","unstructured":"Public Health Agency of Canada. 2020. Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS): 2018 integrated findings. https:\/\/www.canada.ca\/content\/dam\/phac-aspc\/documents\/services\/surveillance\/canadian-integrated-program-antimicrobial-resistance-surveillance-cipars\/cipars-reports\/2018-annual-report-integrated-findings\/2018-annual-report-integrated-findings.pdf. Accessed 22 May 2021."},{"key":"e_1_3_2_43_2","unstructured":"USDA-APHIS-NAHMS. 2020. Antimicrobial use and stewardship on U.S. swine operations 2017. https:\/\/www.aphis.usda.gov\/animal_health\/nahms\/amr\/downloads\/amu-swine.pdf."},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58659-3"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02354-18"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-46718-4_15"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720150469"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10156-012-0532-2"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.14276"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01043-13"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3869"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00062-07"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks1219"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061217"},{"key":"e_1_3_2_55_2","unstructured":"Oksanen J Blanchet FG Kindt R Legendre P Minchin PR O\u2019Hara R Simpson GL Solymos P Stevens MHH Wagner HJ. 2013. Vegan. Community ecology package. R package version 2.5-6. https:\/\/CRAN.R-project.org\/package=vegan."},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11257"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-018-0176-y"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz862"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz935"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky418"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3176"},{"key":"e_1_3_2_64_2","unstructured":"Martinez Arbizu P. 2021. PairwiseAdonis: multilevel comparison using adonis. R package version 04. https:\/\/github.com\/pmartinezarbizu\/pairwiseAdonis."},{"key":"e_1_3_2_65_2","doi-asserted-by":"crossref","unstructured":"Mallick H Rahnavard A McIver LJ Ma S Zhang Y Nguyen LH Tickle TL Weingart G Ren B Schwager EH Chatterjee S Thompson KN Wilkinson JE Subramanian A Lu Y Waldron L Paulson JN Franzosa EA Bravo HC Huttenhower C. 2021. Multivariable association discovery in population-scale meta-omics studies. bioRxiv https:\/\/www.biorxiv.org\/content\/10.1101\/2021.01.20.427420v1.","DOI":"10.1101\/2021.01.20.427420"}],"container-title":["mSystems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSystems.00682-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSystems.00682-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T17:58:51Z","timestamp":1726163931000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mSystems.00682-21"}},"subtitle":[],"editor":[{"given":"Paul D.","family":"Cotter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,12,21]]},"references-count":64,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12,21]]}},"alternative-id":["10.1128\/mSystems.00682-21"],"URL":"https:\/\/doi.org\/10.1128\/msystems.00682-21","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.05.20.444551","asserted-by":"object"}]},"ISSN":["2379-5077"],"issn-type":[{"value":"2379-5077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,21]]},"assertion":[{"value":"2021-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00682-21"}}