{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:40:37Z","timestamp":1791931237379,"version":"4.3.4"},"reference-count":103,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T00:00:00Z","timestamp":1574121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/AuthorWarrantyLicense.v1"},{"start":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T00:00:00Z","timestamp":1576540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSystems"],"published-print":{"date-parts":[[2019,12,17]]},"abstract":"<jats:p>\n            <jats:named-content content-type=\"genus-species\">Bordetella pertussis<\/jats:named-content>\n            is the primary agent of whooping cough (pertussis). The\n            <jats:italic>Bordetella<\/jats:italic>\n            genus includes additional pathogens of animals and humans, including some that cause pertussis-like respiratory illness. The chromosome of\n            <jats:named-content content-type=\"genus-species\">B. pertussis<\/jats:named-content>\n            has previously been shown to exhibit considerable structural rearrangement, but insufficient data have prevented comparable investigation in related species. In this study, we analyze chromosome structure variation in several\n            <jats:italic>Bordetella<\/jats:italic>\n            species to gain a generalized understanding of rearrangement patterns in this genus. Just as in\n            <jats:named-content content-type=\"genus-species\">B. pertussis<\/jats:named-content>\n            , we observed inversions in other species that likely result from common mutational processes. We used these data to further predict additional, unobserved inversions, suggesting that specific genome structures may be preferred in each species.\n          <\/jats:p>","DOI":"10.1128\/msystems.00702-19","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T13:41:52Z","timestamp":1574084512000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":47,"title":["Conserved Patterns of Symmetric Inversion in the Genome Evolution of\n            <i>Bordetella<\/i>\n            Respiratory Pathogens"],"prefix":"10.1128","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7278-0160","authenticated-orcid":false,"given":"Michael R.","family":"Weigand","sequence":"first","affiliation":[{"name":"Division of Bacterial Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhui","family":"Peng","sequence":"additional","affiliation":[{"name":"Division of Bacterial Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhwani","family":"Batra","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Burroughs","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie K.","family":"Davis","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Knipe","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir N.","family":"Loparev","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taccara","family":"Johnson","sequence":"additional","affiliation":[{"name":"Division of Bacterial Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phalasy","family":"Juieng","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori A.","family":"Rowe","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mili","family":"Sheth","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Tang","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvette","family":"Unoarumhi","sequence":"additional","affiliation":[{"name":"Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret M.","family":"Williams","sequence":"additional","affiliation":[{"name":"Division of Bacterial Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Lucia","family":"Tondella","sequence":"additional","affiliation":[{"name":"Division of Bacterial Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"177","article-title":"Phylogenetic relationships and virulence evolution in the genus Bordetella","volume":"264","author":"von Wintzingerode F","year":"2002","unstructured":"von Wintzingerode F, Gerlach G, Schneider B, Gross R. 2002. Phylogenetic relationships and virulence evolution in the genus Bordetella. Curr Top Microbiol Immunol 264:177\u2013199.","journal-title":"Curr Top Microbiol Immunol"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-13-545"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/135.5.753"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(88)90059-4"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2018.07.010"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy469"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/bf02962245"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130964"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2006-7-9-r81"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-016-3112-5"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu001"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01339-14"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01074-14"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200850"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.14939"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2015.05.008"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001295"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.7.635"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70021-0"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2311.170960"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1017\/S095026881200132X"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2011.00911.x"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000262"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ514"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1807.120130"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis888"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2017.10.014"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir860"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.2014.942221"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02368-14"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175587"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00601-11"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03567-14"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.EI10-0003-2015"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00036-16"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00806-16"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.01080-16"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2009.10.007"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780198811879.003.0009"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.179.18.5820-5826.1997"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.181.17.5512-5515.1999"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw647"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01081-06"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1227"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00436-14"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2016.06.003"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01867-14"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00239-005-0192-2"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007421"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03847.x"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600434"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174887"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv709"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1534\/g3.114.016139"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1108229109"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftv055"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1811.111544"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1111\/1348-0421.12409"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006989"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix221"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2010.0010"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1086\/515154"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.1.1"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2003.11.005"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.04.053"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.05.053"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03303.x"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2012.03925.x"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2011.00836.x"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.epidem.2017.12.005"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2504.180812"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2109.150023"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00979-16"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.01404-16"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2202.151332"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00973-17"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00965-15"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00056-13"},{"key":"e_1_3_2_80_2","volume-title":"Molecular cloning: a laboratory manual","author":"Green MR","year":"2012","unstructured":"Green MR, Sambrook J, Sambrook J. 2012. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY."},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2474"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0072-8"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-015-0849-0"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm039"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1005595"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-016-0997-x"},{"key":"e_1_3_2_87_2","volume-title":"Abstr ASM Conf Rapid Appl Microb Next Gener Seq Bioinformatic Pipelines","author":"Katz LS","year":"2017","unstructured":"Katz LS, Griswold T, Carleton HA. 2017. Generating WGS trees with mashtree, poster 27. Abstr ASM Conf Rapid Appl Microb Next Gener Seq Bioinformatic Pipelines. American Society for Microbiology, Washington, DC."},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv271"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw290"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu033"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vew007"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vey016"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syy032"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.1111\/2041-210X.12628"},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr011"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl158"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkj014"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011147"},{"key":"e_1_3_2_99_2","unstructured":"Oksanen J Guillaume Blanchet F Friendly M Kindt R Legendre P McGlinn D Minchin PR O\u2019Hara RB Simpson GL Solymos P Henry M Stevens H Szoecs E Wagner H. 2018. vegan: Community Ecology Package. R package version 2.5-2. https:\/\/CRAN.R-project.org\/package=vegan."},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks990"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-12-19"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v024.i02"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v024.i06"},{"key":"e_1_3_2_104_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu393"}],"container-title":["mSystems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/msystems.00702-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/msystems.00702-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,11]],"date-time":"2024-08-11T19:10:29Z","timestamp":1723403429000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/msystems.00702-19"}},"subtitle":[],"editor":[{"given":"Jack A.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,12,17]]},"references-count":103,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12,17]]}},"alternative-id":["10.1128\/msystems.00702-19"],"URL":"https:\/\/doi.org\/10.1128\/msystems.00702-19","relation":{},"ISSN":["2379-5077"],"issn-type":[{"value":"2379-5077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,17]]},"assertion":[{"value":"2019-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"10.1128\/msystems.00702-19"}}