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Current therapeutic and pharmacologic approaches to treat gonorrhea have been compromised by increased antibiotic resistance worldwide, including to the most recent FDA-approved antibiotic. New treatment strategies are urgently needed to combat this organism. In this study, we used network analysis to interrogate and define the coordination of pathways and processes in\n            <jats:named-content content-type=\"genus-species\">N. gonorrhoeae<\/jats:named-content>\n            . An analysis of the gonococcal network was also used to assign categories to genes and to expand our understanding of regulatory strategies. Network analysis provides important insights into pathogenic mechanisms of this organism that will guide the design of new strategies for disease treatment.\n          <\/jats:p>","DOI":"10.1128\/msystems.00729-19","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T10:33:10Z","timestamp":1580812390000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["Global Network Analysis of Neisseria gonorrhoeae Identifies Coordination between Pathways, Processes, and Regulators Expressed during Human Infection"],"prefix":"10.1128","volume":"5","author":[{"given":"Ryan","family":"McClure","sequence":"first","affiliation":[{"name":"Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini","family":"Sunkavalli","sequence":"additional","affiliation":[{"name":"Department of 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