{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:41:01Z","timestamp":1787506861806,"version":"build-2736575974"},"reference-count":44,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100014180","name":"Junta de Castilla y Le\u00f3n","doi-asserted-by":"crossref","award":["CLU 2017-09"],"award-info":[{"award-number":["CLU 2017-09"]}],"id":[{"id":"10.13039\/501100014180","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100008054","name":"Fundaci\u00f3n Ram\u00f3n Areces","doi-asserted-by":"crossref","award":["ProgStrain"],"award-info":[{"award-number":["ProgStrain"]}],"id":[{"id":"10.13039\/100008054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSystems"],"published-print":{"date-parts":[[2024,2,20]]},"abstract":"<jats:p>\n                    <jats:italic>Paracoccus denitrificans<\/jats:italic>\n                    has been broadly used as a model denitrifying organism. It grows on a large portfolio of carbon sources, under aerobic and anoxic conditions. These characteristics, together with its amenability to genetic manipulations, make\n                    <jats:italic>P. denitrificans<\/jats:italic>\n                    a promising cell factory for industrial biotechnology. This paper presents and validates the first functional genome-scale metabolic model for\n                    <jats:italic>P. denitrificans<\/jats:italic>\n                    , which is a key tool to enable\n                    <jats:italic>P. denitrificans<\/jats:italic>\n                    as a platform for metabolic engineering and industrial biotechnology. Optimization of the biomass yield led to accurate predictions in a broad scope of substrates.\n                  <\/jats:p>","DOI":"10.1128\/msystems.01077-23","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T09:51:11Z","timestamp":1704448271000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Genome-scale metabolic model of the versatile bacterium\n                    <i>Paracoccus denitrificans<\/i>\n                    Pd1222"],"prefix":"10.1128","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6162-6478","authenticated-orcid":false,"given":"Sergio","family":"Bordel","sequence":"first","affiliation":[{"name":"Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Valladolid, Spain"},{"name":"2Institute of Sustainable Processes, Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Mart\u00edn-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Valladolid, Spain"},{"name":"2Institute of Sustainable Processes, Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"B\u00f6rner","sequence":"additional","affiliation":[{"name":"HES-SO Valais\/Wallis, School of Engineering, Institute of Life Technologies, Sion, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Valladolid, Spain"},{"name":"2Institute of Sustainable Processes, Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7986-5557","authenticated-orcid":false,"given":"Fernando","family":"Santos-Beneit","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Valladolid, Spain"},{"name":"2Institute of Sustainable Processes, Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_4_2_2","first-page":"30","article-title":"Bildung und verbrauch von stickoxydul durch bakterien","volume":"25","author":"Beijerinck M","year":"1910","unstructured":"Beijerinck M. 1910 Bildung und verbrauch von stickoxydul durch bakterien. 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