{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:44:23Z","timestamp":1781765063855,"version":"3.54.5"},"reference-count":35,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2021,10,31]],"date-time":"2021-10-31T00:00:00Z","timestamp":1635638400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,10,31]],"date-time":"2021-10-31T00:00:00Z","timestamp":1635638400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873958"],"award-info":[{"award-number":["81873958"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Research and Development Plan","award":["2020YFA0907200"],"award-info":[{"award-number":["2020YFA0907200"]}]},{"name":"National Key Research and Development Plan","award":["2019YFC0840602"],"award-info":[{"award-number":["2019YFC0840602"]}]},{"name":"Guangdong Scientific and Technological Foundation","award":["2019B1515120041"],"award-info":[{"award-number":["2019B1515120041"]}]},{"name":"Guangdong Scientific and Technological Foundation","award":["2020B1111170014"],"award-info":[{"award-number":["2020B1111170014"]}]},{"name":"Guangdong Scientific and Technological Foundation","award":["2020A1515010977"],"award-info":[{"award-number":["2020A1515010977"]}]},{"name":"Guangdong Scientific and Technological Foundation","award":["2019A1515110055"],"award-info":[{"award-number":["2019A1515110055"]}]},{"DOI":"10.13039\/501100019341","name":"Shenzhen Scientific and Technological Foundation","doi-asserted-by":"crossref","award":["KCXFZ202002011007083"],"award-info":[{"award-number":["KCXFZ202002011007083"]}],"id":[{"id":"10.13039\/501100019341","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100019341","name":"Shenzhen Scientific and Technological Foundation","doi-asserted-by":"crossref","award":["JSGG20200225150702770"],"award-info":[{"award-number":["JSGG20200225150702770"]}],"id":[{"id":"10.13039\/501100019341","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Spectr"],"published-print":{"date-parts":[[2021,10,31]]},"abstract":"<jats:p>This study describes how a virus might utilize host aryl hydrocarbon receptor signaling to promote its replication, even in the presence of type I interferons.<\/jats:p>","DOI":"10.1128\/spectrum.00473-21","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T16:21:39Z","timestamp":1635178899000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus"],"prefix":"10.1128","volume":"9","author":[{"given":"Jincheng","family":"Chen","sequence":"first","affiliation":[{"name":"Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China"},{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Liang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"},{"name":"Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xu","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqi","family":"Liu","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyan","family":"Liu","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian","family":"Duan","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Li","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoqin","family":"Wang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingxia","family":"Liu","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0473-2789","authenticated-orcid":true,"given":"Brian","family":"McSharry","sequence":"additional","affiliation":[{"name":"Infections, Immunity and Inflammation, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl G.","family":"Feng","sequence":"additional","affiliation":[{"name":"Infections, Immunity and Inflammation, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3617-5449","authenticated-orcid":true,"given":"Guoliang","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Infectious Diseases, Guangdong Provincial Clinical Research Center for Tuberculosis, The Third People\u2019s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen, China"},{"name":"Infections, Immunity and Inflammation, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2019.06.005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02588-12"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009166"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1008168"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/v11050466"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-016-0433-7"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13684"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2019.12.005"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2015.11.007"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix576"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123851"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2008.10.031"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-013-0395-3"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0048-9697(01)00874-9"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3422"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.2310\/7290.2010.00036"},{"key":"e_1_3_3_18_2","first-page":"54","article-title":"Aryl hydrocarbon receptor negatively regulates type I interferon production and the development of murine lupus","volume":"70","author":"Lee S","year":"2014","unstructured":"Lee S, Ripley B, Chinen I, Millrine D, Kishimoto T. 2014. Aryl hydrocarbon receptor negatively regulates type I interferon production and the development of murine lupus. Cytokine 70:54.","journal-title":"Cytokine"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.1.247"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02061"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd9732"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00958-13"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-020-0664-0"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.30203"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02591-19"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1008664"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2026336118"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.08.009"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.3390\/v11030246"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-81-9-2215"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1002\/jlb.55.3.299"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.05.011"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2021091118"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-020-00435-z"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv363"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a118408"}],"container-title":["Microbiology Spectrum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/Spectrum.00473-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/Spectrum.00473-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T08:56:28Z","timestamp":1646729788000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/Spectrum.00473-21"}},"subtitle":[],"editor":[{"given":"JJ","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,10,31]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,10,31]]}},"alternative-id":["10.1128\/Spectrum.00473-21"],"URL":"https:\/\/doi.org\/10.1128\/spectrum.00473-21","relation":{},"ISSN":["2165-0497"],"issn-type":[{"value":"2165-0497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,31]]},"assertion":[{"value":"2021-06-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00473-21"}}