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We show that DMDC has\n            <jats:italic>in vitro<\/jats:italic>\n            efficacy in a copper-dependent manner and kills pathogens across three different kingdoms,\n            <jats:named-content content-type=\"genus-species\">Streptococcus pneumoniae<\/jats:named-content>\n            (\n            <jats:italic>Sr. pneumoniae<\/jats:italic>\n            ),\n            <jats:italic>Coccidioides posadasii<\/jats:italic>\n            , and\n            <jats:named-content content-type=\"genus-species\">Schistosoma mansoni<\/jats:named-content>\n            , and\n            <jats:italic>in vivo<\/jats:italic>\n            efficacy against\n            <jats:named-content content-type=\"genus-species\">Sr<\/jats:named-content>\n            <jats:named-content content-type=\"genus-species\">. pneumoniae<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/spectrum.00778-21","type":"journal-article","created":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T14:31:51Z","timestamp":1630506711000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Demonstration of\n            <i>N<\/i>\n            ,\n            <i>N<\/i>\n            -Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens"],"prefix":"10.1128","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2056-1879","authenticated-orcid":true,"given":"Sanjay V.","family":"Menghani","sequence":"first","affiliation":[{"name":"Department of Immunobiology, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Rivera","sequence":"additional","affiliation":[{"name":"Department of Immunobiology, University of Arizona, Tucson, Arizona, USA"},{"name":"Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda","family":"Neubert","sequence":"additional","affiliation":[{"name":"Department of Immunobiology, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Hagerty","sequence":"additional","affiliation":[{"name":"Department of Biology, Case Western Reserve University, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Lewis","sequence":"additional","affiliation":[{"name":"Valley Fever Center for Excellence and Department of Medicine, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John N.","family":"Galgiani","sequence":"additional","affiliation":[{"name":"Valley Fever Center for Excellence and Department of Medicine, University of Arizona, Tucson, Arizona, USA"},{"name":"BIO5 Institute, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmitt R.","family":"Jolly","sequence":"additional","affiliation":[{"name":"Department of Biology, Case Western Reserve University, Cleveland, Ohio, USA"},{"name":"Center for Global Health and Disease, Case Western Reserve University, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph W.","family":"Alvin","sequence":"additional","affiliation":[{"name":"Department of Immunobiology, University of Arizona, Tucson, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6347-0208","authenticated-orcid":true,"given":"Michael D. 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