{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:23:32Z","timestamp":1788269012436,"version":"build-2803163510"},"reference-count":37,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Spectr"],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n \n \n Sporotrichosis is a serious fungal disease of humans and animals worldwide. The ongoing epidemic of cat-transmitted sporotrichosis caused by\n Sporothrix brasiliensis<\/jats:italic>\n in South America raises major public health concerns, yet data on environmental persistence and disinfectant efficacy are scarce. Using the quantitative disk carrier method (ASTM 2197), we evaluated persistence and disinfectant susceptibility of\n Sporothrix schenckii<\/jats:italic>\n and\n Sporothrix brasiliensis<\/jats:italic>\n yeasts on hard, non-porous stainless-steel surfaces. Both species remained viable for at least 6 weeks, supporting the potential for fomite-mediated transmission. We tested seven disinfectant formulations. Sodium hypochlorite (NaOCl) 10,000 ppm (1.0%) and 70% isopropyl alcohol achieved >6 Log\n 10<\/jats:sub>\n reduction for both species with 3 min contact time. Intermediate activity was observed with 1,000 ppm (0.1%) NaOCl at 3 min against\n S. schenckii<\/jats:italic>\n . For both species, <3 Log\n 10<\/jats:sub>\n reduction was observed for 100 ppm (0.01%) NaOCl tested at 3 min contact time, and three veterinary-market products\u2014an accelerated hydrogen peroxide product (Product H\n 2<\/jats:sub>\n O\n 2<\/jats:sub>\n ) for 1 min, a quaternary ammonium compound (Product QAC), and a potassium peroxymonosulfate product (Product KPS)\u2014tested at 10 and 5 min, respectively. These results demonstrate prolonged surface survival of\n Sporothrix<\/jats:italic>\n spp. and identify which disinfectants are effective or ineffective under the tested conditions, concentrations, and contact times. This evidence can guide infection-control practices in clinical and veterinary settings. Notably, 70% isopropyl alcohol is a non-corrosive, less irritating alternative, making it useful for protecting animal patients and veterinary equipment.\n <\/jats:p>\n \n IMPORTANCE<\/jats:title>\n \n Cat-transmitted sporotrichosis is an emerging public health concern in South America and is increasingly reported in other continents. Although primarily zoonotic, recent evidence indicates\n Sporothrix<\/jats:italic>\n spp. can be transmitted via contaminated surfaces and fomites, raising the risk of indirect transmission and nosocomial spread. Effective surface disinfection is therefore critical\u2014particularly in veterinary clinics\u2014but guidance is limited by a lack of rigorous testing of disinfectant activity against\n Sporothrix<\/jats:italic>\n species. Our study fills this gap by assessing the environmental persistence of\n Sporothrix schenckii<\/jats:italic>\n and\n Sporothrix brasiliensis<\/jats:italic>\n on surfaces and by evaluating the efficacy of seven disinfectant formulations. These results will inform evidence-based infection-control practices to reduce fomite-mediated transmission and protect human and animal health.\n <\/jats:p>\n <\/jats:sec>\n <\/jats:sec>","DOI":"10.1128\/spectrum.01255-26","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:01:08Z","timestamp":1784552468000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the persistence of\n Sporothrix schenckii<\/i>\n and\n Sporothrix brasiliensis<\/i>\n yeasts on hard, non-porous surfaces and the efficacy of disinfectants"],"prefix":"10.1128","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4023-1415","authenticated-orcid":true,"given":"Bruno C.","family":"Rediguieri","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00qzjvm58","id-type":"ROR","asserted-by":"publisher"}],"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention","place":["Atlanta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa F.","family":"L\u00f3pez","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00qzjvm58","id-type":"ROR","asserted-by":"publisher"}],"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention","place":["Atlanta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Flanagan","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00qzjvm58","id-type":"ROR","asserted-by":"publisher"}],"name":"Clinical and Environmental Microbiology Branch, Centers for Disease Control and Prevention","place":["Atlanta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3099-7334","authenticated-orcid":true,"given":"D. Joseph","family":"Sexton","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00qzjvm58","id-type":"ROR","asserted-by":"publisher"}],"name":"Clinical and Environmental Microbiology Branch, Centers for Disease Control and Prevention","place":["Atlanta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1086-8041","authenticated-orcid":true,"given":"Anastasia P.","family":"Litvintseva","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00qzjvm58","id-type":"ROR","asserted-by":"publisher"}],"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention","place":["Atlanta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof8080776"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0001-37652006000200009"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12281-024-00500-9"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myac079"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myu062"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid3005.231563"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2024.11.003"},{"key":"e_1_3_3_9_2","unstructured":"WHO. 2023. Sporotrichosis. 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Neutralization of microbicidal activity against Candida auris using the quantitative method"}],"container-title":["Microbiology Spectrum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.01255-26","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.01255-26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:08:20Z","timestamp":1788268100000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/spectrum.01255-26"}},"subtitle":[],"editor":[{"given":"Siu-Kei","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9,1]]}},"alternative-id":["10.1128\/spectrum.01255-26"],"URL":"https:\/\/doi.org\/10.1128\/spectrum.01255-26","relation":{},"ISSN":["2165-0497"],"issn-type":[{"value":"2165-0497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,1]]},"assertion":[{"value":"2026-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01255-26"}}