{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:51:52Z","timestamp":1791219112688,"version":"4.1.0"},"reference-count":33,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Spectr"],"published-print":{"date-parts":[[2022,2,23]]},"abstract":"<jats:p>\n            Since\n            <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n            was first detected in South Africa in 2009, health care-associated transmission events and large outbreaks have led to this pathogen accounting for more than 1 in 10 cases of candidemia. A large proportion of South African\n            <jats:named-content content-type=\"genus-species\">C. auris<\/jats:named-content>\n            isolates are highly resistant to fluconazole but variably resistant to amphotericin B and echinocandins.\n          <\/jats:p>","DOI":"10.1128\/spectrum.01717-21","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T21:34:14Z","timestamp":1645652054000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["<i>In Vitro<\/i>\n            Antifungal Activity of Manogepix and Other Antifungal Agents against South African\n            <i>Candida auris<\/i>\n            Isolates from Bloodstream Infections"],"prefix":"10.1128","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6117-4309","authenticated-orcid":true,"given":"Tsidiso G.","family":"Maphanga","sequence":"first","affiliation":[{"name":"National Institute for Communicable Diseases (Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses), National Health Laboratory Service, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth S.","family":"Mpembe","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Diseases (Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses), National Health Laboratory Service, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serisha D.","family":"Naicker","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Diseases (Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses), National Health Laboratory Service, Johannesburg, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7869-9462","authenticated-orcid":true,"given":"Nelesh P.","family":"Govender","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Diseases (Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses), National Health Laboratory Service, Johannesburg, South Africa"},{"name":"School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"},{"name":"Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa"},{"name":"Medical Research Council Centre for Medical Mycology, College of Medicine and Health, University of Exeter, Exeter, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for GERMS-SA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"Centers for Disease Control and Prevention (CDC). Tracking Candida auris countries from which Candida auris cases have been reported as of February 15 2021. https:\/\/www.cdc.gov\/fungal\/candida-auris\/tracking-c-auris.html#historical."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00726"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2509.190686"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2509.190040"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8020181"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2611.203504"},{"key":"e_1_3_2_8_2","first-page":"2","article-title":"Global emergence of a multi-drug resistant fungal pathogen, Candida auris","volume":"31","author":"Britz E","year":"2016","unstructured":"Britz E, Govender NP. 2016. Global emergence of a multi-drug resistant fungal pathogen, Candida auris. South Afr J Infect Dis 31:2.","journal-title":"South Afr J Infect Dis"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.01918"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw691"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07779-6"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0045-x"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.03364-19"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2411.180368"},{"key":"e_1_3_2_15_2","article-title":"Federation of infectious diseases societies of Southern Africa guideline: recommendations for the detection, management and prevention of healthcare-associated Candida auris colonisation and disease in South Africa","volume":"34","author":"Govender NP","year":"2019","unstructured":"Govender NP, Avenant T, Brink A, Chibabhai V, Cleghorn J, Du Toit B, Govind C, Lewis E, Lowman W, Mahlangu H, Maslo C, Messina A, Mer M, Pieton K, Seetharam S, Sriruttan C, Swart K, van Schalkwyk E. 2019. Federation of infectious diseases societies of Southern Africa guideline: recommendations for the detection, management and prevention of healthcare-associated Candida auris colonisation and disease in South Africa. South African J Infect Dis 34.","journal-title":"South African J Infect Dis"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9090568"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00517-21"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx480"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6901a2"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof6010028"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00840-19"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02319-17"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00656-20"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00656-20"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01124-20"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02343-20"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2021.04.012"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof6040239"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01225-18"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky302"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2021.1944323:1-24"},{"key":"e_1_3_2_32_2","volume-title":"Reference method for broth 419 dilution antifungal susceptibility testing of yeasts. 4th Informational Supplement","author":"Clinical and Laboratory Standard Institute","year":"2012","unstructured":"Clinical and Laboratory Standard Institute. 2012. Reference method for broth 419 dilution antifungal susceptibility testing of yeasts. 4th Informational Supplement. 420 Clinical and Laboratory Standards Institute M27-A3, Wayne, PA, USA."},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00782-14"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01377.x"}],"container-title":["Microbiology Spectrum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.01717-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.01717-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T08:46:41Z","timestamp":1646729201000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/spectrum.01717-21"}},"subtitle":[],"editor":[{"given":"Rita Okeoghene","family":"Oladele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,2,23]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2,23]]}},"alternative-id":["10.1128\/spectrum.01717-21"],"URL":"https:\/\/doi.org\/10.1128\/spectrum.01717-21","relation":{},"ISSN":["2165-0497"],"issn-type":[{"value":"2165-0497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,23]]},"assertion":[{"value":"2021-09-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01717-21"}}