{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T16:04:20Z","timestamp":1784649860000,"version":"3.55.0"},"reference-count":35,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T00:00:00Z","timestamp":1676332800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T00:00:00Z","timestamp":1676332800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Guangdong Natural Science Foundation for Distinguished Young Scholar","award":["2020B151502003"],"award-info":[{"award-number":["2020B151502003"]}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"publisher","award":["2019A1515110640"],"award-info":[{"award-number":["2019A1515110640"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shenzhen Key Laboratory of Gene Regulation and Systems Biology","award":["ZDSYS20200811144002008"],"award-info":[{"award-number":["ZDSYS20200811144002008"]}]},{"name":"Shenzhen Science and Technology Program","award":["KQTD20200909113758004"],"award-info":[{"award-number":["KQTD20200909113758004"]}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"publisher","award":["2020A1515010316"],"award-info":[{"award-number":["2020A1515010316"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Spectr"],"published-print":{"date-parts":[[2023,2,14]]},"abstract":"<jats:p>\n            <jats:named-content content-type=\"genus-species\">Pseudomonas aeruginosa<\/jats:named-content>\n            is one predominant pathogen that causes hospital-acquired infections and is one of the commonest coinfecting bacteria in immunocompromised patients and chronic wounds. This bacterium harbors a diverse accessory genome with a high frequency of gene recombination, rendering its population highly heterogeneous.\n          <\/jats:p>","DOI":"10.1128\/spectrum.03308-22","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T14:00:52Z","timestamp":1671717652000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["Acquisition of T6SS Effector TseL Contributes to the Emerging of Novel Epidemic Strains of Pseudomonas aeruginosa"],"prefix":"10.1128","volume":"11","author":[{"given":"Anmin","family":"Ren","sequence":"first","affiliation":[{"name":"School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minlu","family":"Jia","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihong","family":"Liu","sequence":"additional","affiliation":[{"name":"Medical Research Center, Southern University of Science and Technology Hospital, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwen","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3557-1850","authenticated-orcid":true,"given":"Tao","family":"Dong","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Cai","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiuxin","family":"Qu","sequence":"additional","affiliation":[{"name":"Shenzhen Third People\u2019s Hospital, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[{"name":"Medical Research Center, Southern University of Science and Technology Hospital, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2362-0128","authenticated-orcid":true,"given":"Liang","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"},{"name":"Shenzhen Third People\u2019s Hospital, The Second Affiliated Hospital of Southern University of Science and Technology, National Clinical Research Center for Infectious Disease, Shenzhen, Guangdong, People\u2019s Republic of China"},{"name":"Key University Laboratory of Metabolism and Health of Guangdong, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7328-154X","authenticated-orcid":true,"given":"Yingdan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10750"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2011.13"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5462"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41522-018-0076-z"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1719317115"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1214550110"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.108957"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.11.008"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16056"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2016.00061"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.08.094"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.07.012"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1101\/2022.04.11.487527"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10010035"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0602138103"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1819801116"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41396-020-00853-2"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12074"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3185"},{"key":"e_1_3_3_21_2","doi-asserted-by":"crossref","unstructured":"Qu J Cai Z Liu Y Duan X Han S Liu J Zhu Y Jiang Z Zhang Y Zhuo C Liu Y Liu Y Liu L Yang L. 2021. Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted Pseudomonas aeruginosa chronic colonizer 11:641920.","DOI":"10.3389\/fcimb.2021.641920"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micres.2015.01.004"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-021-00950-8"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-022-04140-y"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1814181115"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/1758-2229.12222"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1808469115"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.584751"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-022-00748-z"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2014.04.010"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2019.07.002"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-020-0416-x"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-021-00655-9"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1006\/plas.1999.1441"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2015.11.020"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf505339q"}],"container-title":["Microbiology Spectrum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.03308-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.03308-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T15:00:36Z","timestamp":1676386836000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/spectrum.03308-22"}},"subtitle":[],"editor":[{"given":"Beile","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,2,14]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2,14]]}},"alternative-id":["10.1128\/spectrum.03308-22"],"URL":"https:\/\/doi.org\/10.1128\/spectrum.03308-22","relation":{},"ISSN":["2165-0497"],"issn-type":[{"value":"2165-0497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,14]]},"assertion":[{"value":"2022-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03308-22"}}