{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:19:05Z","timestamp":1788913145248,"version":"build-2803163510"},"reference-count":9,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/AuthorWarrantyLicense.v1"},{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"HHS | CDC | National Center for Emerging and Zoonotic Infectious Diseases"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Spectr"],"published-print":{"date-parts":[[2024,4,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              CHROMagar\n              <jats:italic>Candida<\/jats:italic>\n              Plus is a new formulation of chromogenic media designed for the detection and differentiation of major clinical\n              <jats:italic>Candida<\/jats:italic>\n              species, including\n              <jats:italic>Candida auris<\/jats:italic>\n              . The objective of this study is to evaluate CHROMagar\n              <jats:italic>Candida<\/jats:italic>\n              Plus when used according to manufacturer\u2019s instructions with a panel of 206 fungal isolates and 83 skin-swab specimens originally collected for\n              <jats:italic>C. auris<\/jats:italic>\n              colonization screening. Of the 68\n              <jats:italic>C<\/jats:italic>\n              .\n              <jats:italic>auris<\/jats:italic>\n              isolates tested, 66\/68 displayed the expected light-blue colony morphology and blue halo within 48 h. None of the remaining 138 non-\n              <jats:italic>auris<\/jats:italic>\n              isolates appeared similar to\n              <jats:italic>C. auris<\/jats:italic>\n              . CHROMagar\n              <jats:italic>Candida<\/jats:italic>\n              Plus was, therefore, inclusive to 97% of 68\n              <jats:italic>C<\/jats:italic>\n              .\n              <jats:italic>auris<\/jats:italic>\n              isolates tested and supported visual exclusion of 100% of the 138 non-\n              <jats:italic>C<\/jats:italic>\n              .\n              <jats:italic>auris<\/jats:italic>\n              isolates tested. For the 83 colonization screening specimens, direct plating onto CHROMagar\n              <jats:italic>Candida<\/jats:italic>\n              Plus was 60% sensitive and 100% specific when compared to the enrichment broth gold-standard reference method. In sum, these findings demonstrate the utility of this media when working with isolates but also notable limitations when working with primary skin-swabs specimens when competing yeast species are present.\n            <\/jats:p>\n            <jats:sec>\n              <jats:title>IMPORTANCE<\/jats:title>\n              <jats:p>\n                <jats:italic>Candida auris<\/jats:italic>\n                is an emerging fungal pathogen of public health concern. As it continues to spread, it is important to publish evaluations of new diagnostic tools. In this study, we share our experience with a new chromogenic media which can help distinguish\n                <jats:italic>C. auris<\/jats:italic>\n                from related species.\n              <\/jats:p>\n            <\/jats:sec>\n          <\/jats:sec>","DOI":"10.1128\/spectrum.03564-23","type":"journal-article","created":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T20:27:51Z","timestamp":1708115271000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["Evaluation of CHROMagar\n            <i>Candida<\/i>\n            Plus for the detection of\n            <i>C. auris<\/i>\n            with a panel of 206 fungal isolates and 83 colonization screening skin-swabs"],"prefix":"10.1128","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-5858","authenticated-orcid":false,"given":"Meghan L.","family":"Bentz","sequence":"first","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngoc","family":"Le","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Min","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie S.","family":"Nunnally","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vickie","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Tran","sequence":"additional","affiliation":[{"name":"Washington State Department of Health, State Public Health Agency, Shoreline, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4383-5994","authenticated-orcid":true,"given":"Shawn R.","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1086-8041","authenticated-orcid":true,"given":"Ana","family":"Litvintseva","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth L.","family":"Berkow","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3099-7334","authenticated-orcid":true,"given":"D. Joseph","family":"Sexton","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_3_2","unstructured":"Centers for Disease Control and Prevention. 2013. Tracking Candida auris. Available from: https:\/\/www.cdc.gov\/fungal\/candida-auris\/tracking-c-auris.html"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00921-17"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01223-17"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.1.58-61.1996"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myaa049"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2020.115168"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03220-20"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw691"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-022-00656-3"}],"container-title":["Microbiology Spectrum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.03564-23","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/spectrum.03564-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T15:07:25Z","timestamp":1712070445000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/spectrum.03564-23"}},"subtitle":[],"editor":[{"given":"Sudha","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,4,2]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,2]]}},"alternative-id":["10.1128\/spectrum.03564-23"],"URL":"https:\/\/doi.org\/10.1128\/spectrum.03564-23","relation":{},"ISSN":["2165-0497"],"issn-type":[{"value":"2165-0497","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,2]]},"assertion":[{"value":"2023-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03564-23"}}