{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:19:52Z","timestamp":1765808392914,"version":"3.41.2"},"reference-count":51,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"MEC | Instituto de Salud Carlos III","award":["PI20\/00575"],"award-info":[{"award-number":["PI20\/00575"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Spectr"],"published-print":{"date-parts":[[2024,8,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              There is no precise information available on the entire workload of isolating a specific microorganism in a clinical microbiology laboratory, and the costs associated with it have not been specifically estimated. In this descriptive retrospective study conducted at the microbiology department of a general teaching hospital from January 2021 to December 2022, we assessed the workload associated with identifying\n              <jats:italic>Candida<\/jats:italic>\n              species in all types of clinical samples and patients. Costs were estimated from data obtained from the hospital\u2019s finance department and microbiology laboratory cost records. In 2 years, 1,008,231 samples were processed at our microbiology department, of which 8,775 had one or more\n              <jats:italic>Candida<\/jats:italic>\n              spp. isolates (9,683 total isolates). Overall, 5,151 samples with\n              <jats:italic>Candida<\/jats:italic>\n              spp. were identified from 2,383 inpatients. We isolated\n              <jats:italic>Candida<\/jats:italic>\n              spp. from 515.3 samples\/100,000 population\/year and from 92 samples\/1,000 hospital admissions\/year. By sample type, 90.8% were superficial, mainly mucosal. Only 9.1%\n              <jats:italic>Candida<\/jats:italic>\n              spp. were isolated from deep, usually sterile, samples, being mostly from ordinarily sterile fluids.\n              <jats:italic>Candida albicans<\/jats:italic>\n              was the main species (58.5%) identified, followed by\n              <jats:italic>C. parapsilosis<\/jats:italic>\n              complex,\n              <jats:italic>C. glabrata<\/jats:italic>\n              ,\n              <jats:italic>C. tropicalis,<\/jats:italic>\n              and\n              <jats:italic>C. krusei<\/jats:italic>\n              . In admitted patients, the incidences of samples with\n              <jats:italic>Candida<\/jats:italic>\n              spp. isolates were 302.7 samples\/100,000 population\/year and 54 samples\/1,000 admissions\/year. The average cost of isolating and identifying\n              <jats:italic>Candida<\/jats:italic>\n              spp. was estimated at 25\u20ac per culture-positive sample. To our knowledge, this is the first attempt to gage the workload and costs of\n              <jats:italic>Candida<\/jats:italic>\n              spp. isolation at a hospital microbiology department. These data can help assess the burden and significance of\n              <jats:italic>Candida<\/jats:italic>\n              isolation at other institutions and also help design measures for streamlining.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>IMPORTANCE<\/jats:title>\n            <jats:p>We believe that this work is of interest because at present, there is no really accurate information available on the total workload involved in isolating a specific microorganism in a clinical microbiology laboratory. The costs related to this have also not been described. We have described the unrestricted workload of Candida spp. in all types of samples for all types of species and patients. We believe that this information would be necessary to collect and share this information as well as to collect it in a standardized way to know the current situation of Candida spp. workload in all clinical microbiology laboratories.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/spectrum.03860-23","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T13:02:05Z","timestamp":1720530125000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":1,"title":["<i>Candida<\/i>\n            spp.: the burden of a microorganism in a microbiology department"],"prefix":"10.1128","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7226-8212","authenticated-orcid":false,"given":"Ana","family":"Soriano-Mart\u00edn","sequence":"first","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0516-6371","authenticated-orcid":true,"given":"Roberto","family":"Alonso","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain"},{"name":"CIBER Enfermedades Respiratorias-CIBERES (CB06\/06\/0058), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Machado","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Reigadas","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain"},{"name":"CIBER Enfermedades Respiratorias-CIBERES (CB06\/06\/0058), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5706-5583","authenticated-orcid":false,"given":"Patricia","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain"},{"name":"CIBER Enfermedades Respiratorias-CIBERES (CB06\/06\/0058), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio","family":"Bouza","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},{"name":"Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain"},{"name":"CIBER Enfermedades Respiratorias-CIBERES (CB06\/06\/0058), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","volume-title":"Candidiasis, StatPearls","author":"AN R","year":"2022","unstructured":"AN R, Rafiq NB. 2022. 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