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The cheA and cheB products were essential in producing changes of swimming direction and flagellar rotation. The checC product appeared to be an essential component of the flagellum; however, specific mutational alterations of this component allowed flagellar assembly but prevented directional changes in swimming. Since some cheB mutants changed directions incessantly, this gene product may also serve to control the direction of flagellar rotation in response to chemoreceptor signals. Thus most or all of the common elements in the signalling process were involved in the generation and regulation of changes in the direction of flagellar rotation.<\/jats:p>","DOI":"10.1128\/jb.126.2.758-770.1976","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T16:02:43Z","timestamp":1578067363000},"page":"758-770","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":181,"title":["cheA, cheB, and cheC genes of Escherichia coli and their role in chemotaxis"],"prefix":"10.1128","volume":"126","author":[{"given":"J S","family":"Parkinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1126\/science.153.3737.708","article-title":"Chemotaxis in bacteria","volume":"153","author":"Adler J.","year":"1966","unstructured":"Adler , J. 1966 . 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