{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T13:47:50Z","timestamp":1767275270786,"version":"3.40.5"},"reference-count":41,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            IMP-8 metallo-\u03b2-lactamase was identified in\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Klebsiella pneumoniae<\/jats:named-content>\n            sequence type 252 (ST252), isolated in a Portuguese hospital in 2009.\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>IMP-8<\/jats:sub>\n            was the first gene cassette of a novel class 3 integron, In1144, also carrying the\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>GES-5<\/jats:sub>\n            ,\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>BEL-1<\/jats:sub>\n            , and\n            <jats:italic>aacA4<\/jats:italic>\n            cassettes. In1144 was located on a ColE1-like plasmid, pKP-M1144 (12,029 bp), with a replication region of limited nucleotide similarity to those of other RNA-priming plasmids, such as pJHCMW1. In1144 and pKP-M1144 represent an interesting case of evolution of resistance determinants in Gram-negative bacteria.\n          <\/jats:p>","DOI":"10.1128\/aac.00937-15","type":"journal-article","created":{"date-parts":[[2015,6,2]],"date-time":"2015-06-02T13:55:09Z","timestamp":1433253309000},"page":"5065-5068","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":32,"title":["Characterization of pKP-M1144, a Novel ColE1-Like Plasmid Encoding IMP-8, GES-5, and BEL-1 \u03b2-Lactamases, from a Klebsiella pneumoniae Sequence Type 252 Isolate"],"prefix":"10.1128","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9912-9028","authenticated-orcid":false,"given":"Costas C.","family":"Papagiannitsis","sequence":"first","affiliation":[{"name":"Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic"},{"name":"National Medicines Institute, Warsaw, Poland"}]},{"given":"Monika","family":"Dolejska","sequence":"additional","affiliation":[{"name":"Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic"},{"name":"CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic"}]},{"given":"Radoslaw","family":"Izdebski","sequence":"additional","affiliation":[{"name":"National Medicines Institute, Warsaw, Poland"}]},{"given":"Hana","family":"Dobiasova","sequence":"additional","affiliation":[{"name":"Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic"},{"name":"CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic"}]},{"given":"Vendula","family":"Studentova","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic"}]},{"given":"Francisco J.","family":"Esteves","sequence":"additional","affiliation":[{"name":"Centro Hospitalar, Tr\u00e1s-os-Montes e Alto Douro, Vila Real, Portugal"}]},{"given":"Lennie P. 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