{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:00:22Z","timestamp":1761058822410},"reference-count":19,"publisher":"American Society for Microbiology","issue":"15","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            In previous studies, we have shown that direct protein-protein interaction between the two regulators ArgR and AhrC in\n            <jats:italic>Lactococcus lactis<\/jats:italic>\n            is required for arginine-dependent repression of the biosynthetic\n            <jats:italic>argC<\/jats:italic>\n            promoter and the activation of the catabolic\n            <jats:italic>arcA<\/jats:italic>\n            promoter. Here, we establish the global ArgR and AhrC regulons by transcriptome analyses and show that both regulators are dedicated to the control of arginine metabolism in\n            <jats:italic>L. lactis<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aem.00117-08","type":"journal-article","created":{"date-parts":[[2008,6,7]],"date-time":"2008-06-07T01:11:00Z","timestamp":1212801060000},"page":"4768-4771","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":32,"title":["Transcriptome Analysis of the\n            <i>Lactococcus lactis<\/i>\n            ArgR and AhrC Regulons"],"prefix":"10.1128","volume":"74","author":[{"given":"Rasmus","family":"Larsen","sequence":"first","affiliation":[{"name":"Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL-9751 NN Haren, The Netherlands"}]},{"given":"Sacha A. F. T.","family":"van Hijum","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL-9751 NN Haren, The Netherlands"}]},{"given":"Jan","family":"Martinussen","sequence":"additional","affiliation":[{"name":"Bacterial Physiology and Genetics, BioCentrum-DTU, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark"}]},{"given":"Oscar P.","family":"Kuipers","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL-9751 NN Haren, The Netherlands"}]},{"given":"Jan","family":"Kok","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL-9751 NN Haren, The Netherlands"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-5-r37"},{"key":"e_1_3_2_3_2","first-page":"203","year":"2002","unstructured":"Belitsky, B. R. 2002. Biosynthesis of amino acids of the glutamate and aspartate families, alanine and polyamines, p. 203-231. In A. L. Sonenshein, J. A. Hoch, and R. Losick (ed.), Bacillus subtilis and its closest relatives: from genes to cells. ASM Press, Washington, DC.","journal-title":"Bacillus subtilis and its closest relatives: from genes to cells."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.849004"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/11.15.5007"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1992.tb02008.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M502349200"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1997.4781845.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(92)91044-P"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(93)90706-9"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020691801251"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.4.1147-1157.2004"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M413983200"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/mr.58.4.631-640.1994"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.9.2785-2794.2001"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.18.6059-6069.2004"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/18.20.6097"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.5236"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1089\/10665270252935566"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1055-7903(02)00277-4"}],"container-title":["Applied and Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.00117-08","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AEM.00117-08","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T16:41:04Z","timestamp":1645634464000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AEM.00117-08"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":19,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1128\/AEM.00117-08"],"URL":"https:\/\/doi.org\/10.1128\/aem.00117-08","relation":{},"ISSN":["0099-2240","1098-5336"],"issn-type":[{"value":"0099-2240","type":"print"},{"value":"1098-5336","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8]]},"assertion":[{"value":"2008-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-05-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}