{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T08:10:40Z","timestamp":1769501440550,"version":"3.49.0"},"reference-count":40,"publisher":"American Society for Microbiology","issue":"17","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Environ Microbiol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>\n            <jats:named-content content-type=\"genus-species\">Acinetobacter baumannii<\/jats:named-content>\n            is an important nosocomial pathogen resistant to many, and sometimes all, antibiotics. The\n            <jats:named-content content-type=\"genus-species\">A. baumannii<\/jats:named-content>\n            K2 capsular type has been associated with elevated antibiotic resistance. The capsular depolymerase characterized here fits the new trend of alternative antibacterial agents needed against multidrug-resistant pathogens. They are highly specific, stable, and refractory to resistance, as they do not kill bacteria\n            <jats:italic>per se<\/jats:italic>\n            ; instead, they remove bacterial surface polysaccharides, which diminish the bacterial virulence and expose them to the host immune system.\n          <\/jats:p>","DOI":"10.1128\/aem.00934-19","type":"journal-article","created":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T13:16:03Z","timestamp":1560950163000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":48,"title":["K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from Acinetobacter baumannii Sepsis"],"prefix":"10.1128","volume":"85","author":[{"given":"Hugo","family":"Oliveira","sequence":"first","affiliation":[{"name":"Centre of Biological Engineering, University of Minho, Braga, 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