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The SIRU method distributed the 104 strains into 81 SIRU profiles that could be clustered into 12 groups and 29 singletons. The discriminatory power of the method at the profile level, translated by Simpson's index of diversity (SID), was similar to that of PFGE subtyping (SID = 99.23% versus 99.85%) and slightly higher than that of\n            <jats:italic>spa<\/jats:italic>\n            typing (SID = 97.61%). At the group level, the SIRU SID (93.24%) was lower than that of PFGE typing (95.41%) but higher than that of MLST (SID = 91.77%). The adjusted Rand (AR) coefficient showed that SIRU typing at the group level had the highest congruence with MLST (AR = 0.5736) and with clonal complex (CC) (AR = 0.4963) but the lowest congruence with PFGE subtype (AR = 0.0242). The Wallace coefficient indicated that in the present collection, two strains with the same SIRU profile have a 100% probability of belonging to the same CC, a 90% probability of sharing the same\n            <jats:italic>spa<\/jats:italic>\n            type, and an 83% probability of being classified in the same sequence type. The high discriminatory power of the SIRU method, along with its apparent concordance with MLST results, makes it potentially valuable for\n            <jats:italic>S. aureus<\/jats:italic>\n            short-term epidemiological investigations and population dynamics as well.\n          <\/jats:p>","DOI":"10.1128\/jcm.01537-08","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T02:37:02Z","timestamp":1236220622000},"page":"1300-1308","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["Staphylococcal Interspersed Repeat Unit Typing of\n            <i>Staphylococcus aureus<\/i>\n            : Evaluation of a New Multilocus Variable-Number Tandem-Repeat Analysis Typing Method"],"prefix":"10.1128","volume":"47","author":[{"given":"Teresa","family":"Conceic\u0327a\u0303o","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Genetics, Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica (ITQB), Oeiras, Portugal"}]},{"given":"Marta","family":"Aires de Sousa","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Genetics, Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica (ITQB), Oeiras, Portugal"},{"name":"Escola Superior de Sau\u0301de da Cruz Vermelha Portuguesa (ESSCVP), Lisbon, Portugal"}]},{"given":"Hermi\u0301nia","family":"de Lencastre","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Genetics, Instituto de Tecnologia Qui\u0301mica e Biolo\u0301gica (ITQB), Oeiras, Portugal"},{"name":"Laboratory of Microbiology, The Rockefeller University, New York, New York"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.2.619-621.2006"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00692-08"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00019-07"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.5.2027-2032.2003"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.10.5150-5157.2005"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.1.159-163.2003"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.8.3806-3815.2003"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2000.6.253"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.6.2197-2205.2001"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.9.2590-2596.1998"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/107662900419447"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/10766290260469561"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00603-07"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08713-5"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02536-05"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2000.6.189"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01794.x"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.1998.4.277"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.161272898"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/344326"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02026129"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.9.2121-2124.1996"},{"key":"e_1_3_2_24_2","first-page":"289","volume":"3","year":"1997","unstructured":"de Lencastre, H., E. 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