{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:34:29Z","timestamp":1780443269025,"version":"3.54.1"},"reference-count":43,"publisher":"Pleiades Publishing Ltd","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biochemistry Moscow"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1134\/s0006297924030155","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T14:02:11Z","timestamp":1712584931000},"page":"574-582","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Protective Activity of Inactivated Rabies Vaccine Using Flagellin-Based Adjuvant"],"prefix":"10.1134","volume":"89","author":[{"given":"Olga O.","family":"Sokol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolai A.","family":"Nikitin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina A.","family":"Evtushenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga V.","family":"Karpova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina N.","family":"Matveeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana A.","family":"Gryn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera M.","family":"Popova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor V.","family":"Ivanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri N.","family":"Fedorov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina Y.","family":"Litenkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"137","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"2664_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines11040756","volume":"11","author":"K. Natesan","year":"2023","unstructured":"Natesan, K., Isloor, S., Vinayagamurthy, B., Ramakrishnaiah, S., Doddamane, R., and Fooks, A.\u00a0R. (2023) Developments in rabies vaccines: the path traversed from Pasteur to the modern era of immunization, Vaccines, 11, 756, \nhttps:\/\/doi.org\/10.3390\/vaccines11040756.","journal-title":"Vaccines"},{"key":"2664_CR2","unstructured":"Wilbur, L. A., and Aubert, M. F. A. (1996) The\u00a0NIH test for potency, in Laboratory Techniques in Rabies, 4th Edn (Meslin F.\u00a0X., Kaplan M.\u00a0M., and Koprowski, H., ed) Geneva, Switzerland: World Health Organisation, 360-368."},{"key":"2664_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.988738","volume":"13","author":"I. Matveeva","year":"2022","unstructured":"Matveeva, I., Karpova, O., Nikitin, N., Akilin, O., Yelnikov, V., Litenkova, I., Melnik, R., Melnik, N., Asimov, K., Zaberezhny, A., Fyodorov, Y., and Markova, E. (2022) Long-term humoral immunogenicity, safety and protective efficacy of inactivated vaccine against reindeer rabies, Front. Microbiol., 13, 988738, \nhttps:\/\/doi.org\/10.3389\/fmicb.2022.988738.","journal-title":"Front. Microbiol."},{"key":"2664_CR4","doi-asserted-by":"publisher","DOI":"10.26717\/BJSTR.2019.16.002850","volume":"16","author":"V. Nedosekov","year":"2019","unstructured":"Nedosekov, V., Polupan, I., and Slivko, I. (2019) Veterinary Vaccine Potency Testing: Improvement of the NIH\u00a0Method, Biomed.\u00a0J. Sci. Tech. Res., 16, 002850, \nhttps:\/\/doi.org\/10.26717\/BJSTR.2019.16.002850.","journal-title":"Biomed.\u00a0J. Sci. Tech. Res."},{"key":"2664_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15061687","volume":"15","author":"J. Y. Kim","year":"2023","unstructured":"Kim, J. Y., Rosenberger, M. G., Rutledge, N. S., and Esser-Kahn, A. P. (2023) Next-generation adjuvants: applying engineering methods to create and evaluate novel immunological responses, Pharmaceutics, 15, 1687, \nhttps:\/\/doi.org\/10.3390\/pharmaceutics15061687.","journal-title":"Pharmaceutics"},{"key":"2664_CR6","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1016\/j.vaccine.2009.01.091","volume":"27","author":"H. X. Sun","year":"2009","unstructured":"Sun, H. X., Xie, Y., and Ye, Y. P. (2009) Advances in saponin-based adjuvants, Vaccine, 27, 1787-1796, \nhttps:\/\/doi.org\/10.1016\/j.vaccine.2009.01.091.","journal-title":"Vaccine"},{"key":"2664_CR7","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.vaccine.2010.07.021","volume":"28","author":"G. Leroux-Roels","year":"2010","unstructured":"Leroux-Roels, G. (2010) Unmet needs in modern vaccinology: adjuvants to improve the immune response, Vaccine, 28, 25-36, \nhttps:\/\/doi.org\/10.1016\/j.vaccine.2010.07.021.","journal-title":"Vaccine"},{"key":"2664_CR8","doi-asserted-by":"publisher","first-page":"3167","DOI":"10.1016\/j.vaccine.2019.04.055","volume":"37","author":"S. Shi","year":"2019","unstructured":"Shi, S., Zhu, H., Xia, X., Liang, Z., Ma, X., and Sun, B. (2019) Vaccine adjuvants: understanding the structure and mechanism of adjuvanticity, Vaccine, 37, 3167-3178, \nhttps:\/\/doi.org\/10.1016\/j.vaccine.2019.04.055.","journal-title":"Vaccine"},{"key":"2664_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.106717","volume":"86","author":"T. Gupta","year":"2020","unstructured":"Gupta, T., and Gupta, S. K. (2020) Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses, Int.\u00a0Immunopharmacol., 86, 106717, \nhttps:\/\/doi.org\/10.1016\/j.intimp.2020.106717.","journal-title":"Int.\u00a0Immunopharmacol."},{"key":"2664_CR10","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1016\/S0264-410X(03)00045-8","volume":"21","author":"S. A. Halperin","year":"2003","unstructured":"Halperin, S. A., Van Nest, G., Smith, B., Abtahi, S., Whiley, H., and Eiden, J. J. (2003) A\u00a0phase\u00a0I study of the safety and immunogenicity of recombinant hepatitis\u00a0B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant, Vaccine, 21, 2461-2467, \nhttps:\/\/doi.org\/10.1016\/S0264-410X(03)00045-8.","journal-title":"Vaccine"},{"key":"2664_CR11","doi-asserted-by":"publisher","first-page":"3377","DOI":"10.1016\/j.bmc.2007.12.008","volume":"16","author":"C. Soldi","year":"2008","unstructured":"Soldi, C., Pizzolatti, M. G., Luiz, A. P., Marcon, R., Meotti, F. C., Mioto, L. A., and Santos, A. R. (2008) Synthetic derivatives of the alpha- and beta-amyrin triterpenes and their antinociceptive properties, Bioorg. Med. Chem., 16, 3377-3386, \nhttps:\/\/doi.org\/10.1016\/j.bmc.2007.12.008.","journal-title":"Bioorg. Med. Chem."},{"key":"2664_CR12","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1002\/jps.21523","volume":"98","author":"J. H. Wilson-Welder","year":"2009","unstructured":"Wilson-Welder, J. H., Torres, M. P., Kipper, M. J., Mallapragada, S. K., Wannemuehler, M. J., and Narasimhan, B. (2009) Vaccine adjuvants: current challenges and future approaches, J.\u00a0Pharm. Sci., 98, 1278-1316, \nhttps:\/\/doi.org\/10.1002\/jps.21523.","journal-title":"J.\u00a0Pharm. Sci."},{"key":"2664_CR13","doi-asserted-by":"publisher","first-page":"182","DOI":"10.4236\/wjv.2012.24025","volume":"2","author":"A. Montaner","year":"2012","unstructured":"Montaner, A., Nichilo, A., Rodriguez, J., Hernando-Insua, A., Fl\u00f3, J., Lopez, R., Sierra, V., Paolazzi, C., Larghi, O., Horn, D., Zorzopulos, J., and Elias, F. (2012) IMT504: a new and potent adjuvant for rabies vaccines permitting significant dose sparing, World J. Vaccines, 2, 182-188, \nhttps:\/\/doi.org\/10.4236\/wjv.2012.24025.","journal-title":"World J. Vaccines"},{"key":"2664_CR14","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1016\/j.imbio.2013.05.006","volume":"218","author":"X. Hu","year":"2013","unstructured":"Hu, X., Liu, R., and Zhu, N. (2013) Enhancement of humoral and cellular immune responses by monophosphoryl lipid\u00a0A (MPLA) as an adjuvant to the rabies vaccine in BALB\/c mice, Immunobiology, 218, 1524-1528, \nhttps:\/\/doi.org\/10.1016\/j.imbio.2013.05.006.","journal-title":"Immunobiology"},{"key":"2664_CR15","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.immuni.2010.10.002","volume":"33","author":"R. L. Coffman","year":"2010","unstructured":"Coffman, R. L., Sher, A., and Seder, R. A. (2010) Vaccine adjuvants: putting innate immunity to work, Immunity, 33, 492-503, \nhttps:\/\/doi.org\/10.1016\/j.immuni.2010.10.002.","journal-title":"Immunity"},{"key":"2664_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-018-0433-5","volume":"25","author":"L. A. Stepanova","year":"2018","unstructured":"Stepanova, L. A., Mardanova, E. S., Shuklina, M. A., Blokhina, E. A., Kotlyarov, R. Y., Potapchuk, M.\u00a0V., Kovaleva, A.\u00a0A., Vidyaeva, I.\u00a0G., Korotkov, A.\u00a0V., Eletskaya, E.\u00a0I., Ravin, N.\u00a0V., and Tsybalova, L.\u00a0M. (2018) Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes, J.\u00a0Biomed. Sci., 25, 33, \nhttps:\/\/doi.org\/10.1186\/s12929-018-0433-5.","journal-title":"J.\u00a0Biomed. Sci."},{"key":"2664_CR17","doi-asserted-by":"publisher","first-page":"7","DOI":"10.17816\/MAJ1727-20","volume":"17","author":"G. A. Sofronov","year":"2017","unstructured":"Sofronov, G. A., Murzina, E. V., Bolekhan, V. N., Veselova, O. M., and Simbirtsev, A. S. (2017) Perspective directions using flagellin based drugs, Med. Acad.\u00a0J., 17, 7-20, \nhttps:\/\/doi.org\/10.17816\/MAJ1727-20.","journal-title":"Med. Acad.\u00a0J."},{"key":"2664_CR18","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1080\/14760584.2018.1457443","volume":"17","author":"B. Cui","year":"2018","unstructured":"Cui, B., Liu, X., Fang, Y., Zhou, P., Zhang, Y., and Wang, Y. (2018) Flagellin as a vaccine adjuvant, Expert Rev. Vaccines, 17, 335-349, \nhttps:\/\/doi.org\/10.1080\/14760584.2018.1457443.","journal-title":"Expert Rev. Vaccines"},{"key":"2664_CR19","first-page":"57","volume":"2015","author":"A. Daas","year":"2015","unstructured":"Daas, A., Bruckner, L., and Milne, C. (2015) EDQM biological reference preparation for rabies vaccine (inactivated) for veterinary use, Pharmeur. Bio. Sci. Notes, 2015, 57-72.","journal-title":"Pharmeur. Bio. Sci. Notes"},{"key":"2664_CR20","doi-asserted-by":"publisher","first-page":"211","DOI":"10.14573\/altex.1501261","volume":"32","author":"M. J. Schiffelers","year":"2015","unstructured":"Schiffelers, M. J., Blaauboer, B. J., Bakker, W. E., and Hendriksen, C. F. (2015) Regulatory acceptance and use of serology for inactivated veterinary rabies vaccines, ALTEX, 32, 211-221, \nhttps:\/\/doi.org\/10.14573\/altex.1501261.","journal-title":"ALTEX"},{"key":"2664_CR21","first-page":"75","volume":"3","author":"A. N. Grebenyuk","year":"2013","unstructured":"Grebenyuk, A. N., Aksenova, N. V., Petrov, A. V., Al-Shhadat, R. I., Klimov, N. A., and Simbirtsev, A. S. (2013) Expression of different variants of recombinant flagellin and study of their radioprotective efficacy [in Russian], Vestnik Russ. Voen. Med. Akad., 3, 75-80.","journal-title":"Vestnik Russ. Voen. Med. Akad."},{"key":"2664_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142415","volume":"10","author":"N. Nikitin","year":"2015","unstructured":"Nikitin, N., Trifonova, E., Evtushenko, E., Kirpichnikov, M., Atabekov, J., and Karpova, O. (2015) Comparative study of non-enveloped Icosahedral viruses size, PLoS One, 10, e0142415, \nhttps:\/\/doi.org\/10.1371\/journal.pone.0142415.","journal-title":"PLoS One"},{"key":"2664_CR23","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1093\/oxfordjournals.aje.a118408","volume":"27","author":"L. J. Reed","year":"1938","unstructured":"Reed, L. J., and Muench, H. (1938) A\u00a0simple method of estimating fifty per cent end points, Am.\u00a0J. Hyg., 27, 493-497, \nhttps:\/\/doi.org\/10.1093\/oxfordjournals.aje.a118408.","journal-title":"Am.\u00a0J. Hyg."},{"key":"2664_CR24","unstructured":"Szaret, P. (1996) General consideration in testing the safety and potency of rabies vaccine, in Laboratory Techniques in Rabies, 4th Edn (Meslin, F.\u00a0X., Kaplan, M.\u00a0M., and Koprowski, H., eds) Geneva, Switzerland, World Health Organisation, pp.\u00a0355-359."},{"key":"2664_CR25","unstructured":"Ashmarin, I. P., and Vorobiev, A. A. Statisticheskiye metody v mikrobiologicheskikh issledovaniyakh, (Statistical methods in microbiological studies), Leningrad: Medgiz, 1962."},{"key":"2664_CR26","unstructured":"Rupprecht, C. E., Fooks, A. R., and Abela-Ridder, B. (2018) Laboratory techniques in rabies, World Health Organization, 5th Edn, Vol.\u00a01, 108-123."},{"key":"2664_CR27","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.biologicals.2011.12.011","volume":"40","author":"A. Servat","year":"2012","unstructured":"Servat, A., Picard-Meyer, E., Robardet, E., Muizniece, Z., Must, K., and Cliquet, F. (2012) Evaluation of a rapid immunochromatographic diagnostic test for the detection of rabies from brain material of European mammals, Biologicals, 40, 61-66, \nhttps:\/\/doi.org\/10.1016\/j.biologicals.2011.12.011.","journal-title":"Biologicals"},{"key":"2664_CR28","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.biologicals.2012.07.005","volume":"40","author":"W. Stokes","year":"2012","unstructured":"Stokes, W., Mcfarland, R., Kulpa-Eddy, J., Gatewood, D., Levis, R., Halder, M., Pulle, G., Kojima, H., Casey, W., Gaydamaka, A., Miller, T., Brown, K., Lewis, C., Chapsal, J. M., Bruckner, L., Gairola, S., Kamphuis, E., Rupprecht, C. E., Wunderli, P., McElhinney, L., De Mattia, F., Gamoh, K., Hill, R., Reed, D., Doelling, V., Johnson, N., Allen, D., Rinckel, L., and Jones, B. (2012) Report on the international workshop on alternative methods for human and veterinary rabies vaccine testing: State of the science and planning the way forward, Biologicals, 40, 369-381, \nhttps:\/\/doi.org\/10.1016\/j.biologicals.2012.07.005.","journal-title":"Biologicals"},{"key":"2664_CR29","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.biologicals.2020.07.010","volume":"68","author":"A. Akkermans","year":"2020","unstructured":"Akkermans, A., Chapsal, J. M., Coccia, E. M., Depraetere, H., Dierick, J. F., Duangkhae, P., Goel, S., Halder, M., Hendriksen, C., Levis, R., Pinyosukhee, K., Pullirsch, D., Sanyal, G., Shi, L., Sitrin, R., Smith, D., Stickings, P., Terao, E., Uhlrich, S., Viviani, L., and Webster, J. (2020) Animal testing for vaccines. Implementing replacement, reduction and refinement: challenges and priorities, Biologicals, 68, 92-107, \nhttps:\/\/doi.org\/10.1016\/j.biologicals.2020.07.010.","journal-title":"Biologicals"},{"key":"2664_CR30","first-page":"133","volume":"13","author":"H. Lin","year":"1999","unstructured":"Lin, H., and Perrin, P. (1999) Influence of aluminum adjuvant to experimental rabies vaccine, Chin.\u00a0J. Exp. Clin. Virol., 13, 133-135.","journal-title":"Chin.\u00a0J. Exp. Clin. Virol."},{"key":"2664_CR31","doi-asserted-by":"publisher","first-page":"13406","DOI":"10.1074\/jbc.M500687200","volume":"280","author":"L. S. Jones","year":"2005","unstructured":"Jones, L. S., Peek, L. J., Power, J., Markham, A., Yazzie, B., and Middaugh, C.\u00a0R. (2005) Efects of adsorption to aluminum salt adjuvants on the structure and stability of model protein antigens, J.\u00a0Biol. Chem., 280, 13406-13414, \nhttps:\/\/doi.org\/10.1074\/jbc.M500687200.","journal-title":"J.\u00a0Biol. Chem."},{"key":"2664_CR32","doi-asserted-by":"publisher","DOI":"10.3389\/fmmu.2012.00406","volume":"3","author":"H. Hogenesch","year":"2013","unstructured":"Hogenesch, H. (2013) Mechanisms of immunopotentiation and safety of aluminium adjuvants, Front. Immunol., 3, 406, \nhttps:\/\/doi.org\/10.3389\/fmmu.2012.00406.","journal-title":"Front. Immunol."},{"key":"2664_CR33","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-29858-w","volume":"8","author":"Y. J. Lin","year":"2018","unstructured":"Lin, Y. J., Shih, Y. J., Chen, C. H., and Fang, C. T. (2018) Aluminum salts as an adjuvant for pre-pandemic infuenza vaccines: a meta-analysis, Sci. Rep., 8, 11460, \nhttps:\/\/doi.org\/10.1038\/s41598-018-29858-w.","journal-title":"Sci. Rep."},{"key":"2664_CR34","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-018-1089-1","volume":"15","author":"P. Yu","year":"2018","unstructured":"Yu, P., Yan, J., Wu, W., Tao, X., Lu, X., Liu, S., and Zhu, W. (2018) A\u00a0CpG oligodeoxynucleotide enhances the immune response to rabies vaccination in mice, Virol.\u00a0J., 15, 174, \nhttps:\/\/doi.org\/10.1186\/s12985-018-1089-1.","journal-title":"Virol.\u00a0J."},{"key":"2664_CR35","first-page":"46","volume":"6","author":"Zh. I. Avdeeva","year":"2007","unstructured":"Avdeeva, Zh. I., Akolzina, S. E., Alpatova, N. A., Movseyants, A.\u00a0A., and Medunitsyn, N.\u00a0V. (2007) Effect of cytokines on protective properties of anti-rabies vaccine [in Russian], Tsitokiny Vospal., 6, 46-50.","journal-title":"Tsitokiny Vospal."},{"key":"2664_CR36","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.virol.2015.10.029","volume":"489","author":"Y. Zhang","year":"2016","unstructured":"Zhang, Y., Zhang, S., Li, W., Hu, Y., Zhao, J., Liu, F., Lin, H., Liu, Y., Wang, L., Xu, S., Hu, R., Shao, H., and Li, L. (2016) A\u00a0novel rabies vaccine based-on toll-like receptor\u00a03 (TLR3) agonist PIKA adjuvant exhibiting excellent safety and efficacy in animal studies, Virology, 489, 165-172, \nhttps:\/\/doi.org\/10.1016\/j.virol.2015.10.029.","journal-title":"Virology"},{"key":"2664_CR37","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1016\/j.dib.2018.10.030","volume":"21","author":"N. A. Nikitin","year":"2018","unstructured":"Nikitin, N. A., Matveeva, I. N., Trifonova, E. A., Puhova, N. M., Samuylenko, A. Y., Gryn, S. A., Atabekov, J. G., and Karpova, O.\u00a0V. (2018) Spherical particles derived from TMV virions enhance the protective properties of the rabies vaccine, Data Brief, 21, 742-745, \nhttps:\/\/doi.org\/10.1016\/j.dib.2018.10.030.","journal-title":"Data Brief"},{"key":"2664_CR38","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.vaccine.2006.08.013","volume":"25","author":"J. W. Huleatt","year":"2006","unstructured":"Huleatt, J. W., Jacobs, A. R., Tang, J., Desai, P., Kopp, E. B., Huang, Y., Song, L., Nakaar, V., and Powell, T.\u00a0J. (2006) Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity, Vaccine, 25, 763-775, \nhttps:\/\/doi.org\/10.1016\/j.vaccine.2006.08.013.","journal-title":"Vaccine"},{"key":"2664_CR39","doi-asserted-by":"publisher","DOI":"10.1038\/emm.2017.172","volume":"49","author":"I. A. Hajam","year":"2017","unstructured":"Hajam, I. A., Dar, P. A., Shahnawaz, I., Jaume, J. C., and Lee, J. H. (2017) Bacterial flagellin\u00a0\u2013 a potent immunomodulatory agent, Exp. Mol. Med., 49, e373, \nhttps:\/\/doi.org\/10.1038\/emm.2017.172.","journal-title":"Exp. Mol. Med."},{"key":"2664_CR40","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.coi.2010.04.004","volume":"22","author":"M. L. Mbow","year":"2010","unstructured":"Mbow, M. L., De Gregorio, E., Valiante, N. M., and Rappuoli, R. (2010) New adjuvants for human vaccines, Curr. Opin. Immunol., 22, 411-416, \nhttps:\/\/doi.org\/10.1016\/j.coi.2010.04.004.","journal-title":"Curr. Opin. Immunol."},{"key":"2664_CR41","doi-asserted-by":"publisher","first-page":"4103","DOI":"10.1016\/j.vaccine.2009.07.058","volume":"28","author":"I. Skountzou","year":"2010","unstructured":"Skountzou, I., Martin, M., Wang, B., Ye, L., Koutsonanos, D., Weldon, W., Jacob, J., and Compans, R.\u00a0W. (2010) Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine, Vaccine, 28, 4103-4112, \nhttps:\/\/doi.org\/10.1016\/j.vaccine.2009.07.058.","journal-title":"Vaccine"},{"key":"2664_CR42","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1086\/517613","volume":"195","author":"W. F. McDonald","year":"2007","unstructured":"McDonald, W. F., Huleatt, J. W., Foellmer, H. G., Hewitt, D., Tang, J., Desai, P., Price, A., Jacobs, A., Takahashi, V.\u00a0N., Huang, Y., Nakaar, V., Alexopoulou, L., Fikrig, E., and Powell, T.\u00a0J. (2007) A\u00a0West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity, J.\u00a0Infect. Dis., 195, 1607-1617, \nhttps:\/\/doi.org\/10.1086\/517613.","journal-title":"J.\u00a0Infect. Dis."},{"key":"2664_CR43","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s00705-015-2704-8","volume":"161","author":"X. X. Xiao","year":"2016","unstructured":"Xiao, X. X., Zhang, Y., Liu, J. X., Wei, Q. L., and Yin, X. P. (2016) Immunoenhancement with flagellin as an adjuvant to whole-killed rabies vaccine in mice, Arch. Virol., 161, 685-691, \nhttps:\/\/doi.org\/10.1007\/s00705-015-2704-8.","journal-title":"Arch. Virol."}],"container-title":["Biochemistry (Moscow)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1134\/S0006297924030155.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1134\/S0006297924030155","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1134\/S0006297924030155.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:18:41Z","timestamp":1773620321000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1134\/S0006297924030155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["2664"],"URL":"https:\/\/doi.org\/10.1134\/s0006297924030155","relation":{},"ISSN":["0006-2979","1608-3040"],"issn-type":[{"value":"0006-2979","type":"print"},{"value":"1608-3040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"6 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All international, national and\/or institutional standards for handling laboratory animals were met. The authors of this work declare that they have no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}}]}}