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The consent procedure and the design of the study were approved by the ethical committee of Vitamed Clinic, Moscow, protocol date\u00a016.10.17. The authors M.\u00a0Sorokin and A.\u00a0Buzdin were employed by the company OmicsWay Corp. The\u00a0authors declare that this study received funding from OmicsWay Corp. The funder had the following involvement in the study: data analysis and interpretation as well as the writing of this manuscript. The funder was not involved in the study design, collection of data, decision to submit this article for publication. The authors of this work declare that they have no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}}]}}