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Animal experiments complied with the requirements of Directive 2010\/63\/EU of the European Parliament and the Council of the European Union on the protection of animals used for scientific purposes (22.09.2010), as well as the provisions of the Eurasian Economic Commission Council Decision no.\u00a081 of\u00a03.11.2016 \u201cOn approval of Rules of good laboratory practice of the Eurasian Economic Union in the sphere of circulation of medicines\u201d and GOST 33215-2014. All\u00a0proposed requirements, including the use of a minimum necessary number of animals, are met.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}},{"value":"Conflict of interest.\n                      The authors of this work declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}}]}}