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These authorizations permit the use of ocular tissues obtained postmortem for both transplantation and scientific research purposes. In\u00a0accordance with the Scientific Cooperation Agreement no.\u00a0137 dated June\u00a08, 2011 between the Center for Fundamental and Applied Biomedical Problems of the Eye Microsurgery Complex and the Emanuel Institute of Biochemical Physics, approval was granted by the Chief Physician of the Eye Microsurgery Complex to conduct experimental studies in the Laboratory of Physicochemical Foundations of Receptor Processes at Institute of Biochemical Physics using RPE derived from cadaveric eyes. Prior to tissue use, donor material was subjected to mandatory serological screening for HIV types\u00a0I and\u00a0II, hepatitis\u00a0B and\u00a0C viruses, and syphilis. Following corneal retrieval for transplantation purposes, the remaining ocular tissues were transferred by the Eye Tissue Bank to Institute of Biochemical Physics in a certified container designed for the transport of human biological materials. After isolation of the RPE, the remaining cadaveric ocular material was returned to the Eye Tissue Bank for disposal in accordance with established bioethical and regulatory procedures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}},{"value":"Conflict of interest.\n                      The authors of this work declare that they have no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}}]}}