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Biomaterial was collected at Pavlov First Saint-Petersburg State Medical University with the permission of the ethics committee (Protocol number:\u00a0244, Approval Date: 25\u00a0January\u00a02021) and FSBI Federal Neurosurgical Center ethics committee approval (Protocol number:\u00a01, Approval Date: 14\u00a0March\u00a02017). Written informed consent or assent was obtained from the patients prior to sample collection. All research was conducted anonymously. The authors confirm that this study was not pre-registered, and blinding was not performed.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}},{"value":"Conflict of interest.\n                      The authors of this work declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declarations"}}]}}