{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:35:07Z","timestamp":1788910507874,"version":"build-2803163510"},"reference-count":26,"publisher":"Pleiades Publishing Ltd","issue":"1","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Russ J Bioorg Chem"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1134\/s1068162023010053","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T16:02:34Z","timestamp":1671724954000},"page":"127-138","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Design, Synthesis, Anti-Tubercular Evaluation and Teratogenicity Studies of Furanyl Pyrazolo[3,4-b] Quinoline-5-Ones"],"prefix":"10.1134","volume":"49","author":[{"given":"N. R.","family":"Babu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. S.","family":"Raju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. R.","family":"Alavala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Malothu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Padmavathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"137","published-online":{"date-parts":[[2022,12,22]]},"reference":[{"key":"8587_CR1","unstructured":"World Health Organization. Global Tuberculosis Report 2021, 2021."},{"key":"8587_CR2","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/j.bmc.2004.09.017","volume":"13","author":"R. Jain","year":"2003","unstructured":"Jain, R., Vaitilingam, B., Nayyar, A. and Palde, P.B., Bioorg. Med. Chem. Lett., 2003, vol. 13, pp. 1051\u20131054. https:\/\/doi.org\/10.1016\/j.bmc.2004.09.017","journal-title":"Bioorg. Med. Chem. Lett"},{"key":"8587_CR3","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.ejmech.2015.03.024","volume":"183","author":"N. Nayak","year":"2016","unstructured":"Nayak, N., Ramprasad, J., and Dalimba, U., J. Fluor. Chem., 2016, vol. 183, pp. 59\u201368. https:\/\/doi.org\/10.1016\/j.ejmech.2015.03.024","journal-title":"J. Fluor. Chem"},{"key":"8587_CR4","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1001\/archinte.163.9.1009","volume":"163","author":"E.L. Corbett","year":"2003","unstructured":"Corbett, E.L., Watt, C.J., Walker, N., Maher, D., Williams, B.G., Raviglione, M.C., and Dye, C., Arch. Int. Med., 2003, vol. 163, pp. 1009\u20131021. https:\/\/doi.org\/10.1001\/archinte.163.9.1009","journal-title":"Arch. Int. Med"},{"key":"8587_CR5","doi-asserted-by":"publisher","unstructured":"Mahajan., R., Int. J. App. Basic Med. Res., 2013, vol. 3, pp. 1\u20133. https:\/\/doi.org\/10.4103\/ijabmr.ijabmr_7_18","DOI":"10.4103\/ijabmr.ijabmr_7_18"},{"key":"8587_CR6","doi-asserted-by":"publisher","first-page":"3271","DOI":"10.1128\/aac.06126-11","volume":"56","author":"A.H. Diacon","year":"2012","unstructured":"Diacon, A.H., Donald, P.R., Pym, A., Grobusch, M., Patientia, R.F., Mahanyele, R., Bantubani, N., Narasimooloo, R., De Marez, T., Van Heeswijk, R., and Lounis, N., Antimicrob. Agents Chemother.,\u00a02012, vol. 56, pp. 3271\u20133276. https:\/\/doi.org\/10.1128\/aac.06126-11","journal-title":"Antimicrob. Agents Chemother"},{"key":"8587_CR7","doi-asserted-by":"publisher","first-page":"105507","DOI":"10.1038\/cdd.2012.115","volume":"165","author":"C.X. Liu","year":"2022","unstructured":"Liu, C.X., Zhao, X., Wang, L., and Yang, Z.C., Microb. Pathog.,\u00a02022,\u00a0vol. 165, p. 105507. https:\/\/doi.org\/10.1038\/cdd.2012.115","journal-title":"Microb. Pathog"},{"key":"8587_CR8","doi-asserted-by":"publisher","first-page":"3374","DOI":"10.1016\/j.ejmech.2010.04.022","volume":"45","author":"S. Eswaran","year":"2010","unstructured":"Eswaran, S., Adhikari, A.V., Chowdhury, I.H., Pal, N.K., and Thomas, K.D.,\u00a0Eur. J. Med. Chem., 2010, vol.\u00a045, pp. 3374\u20133383. https:\/\/doi.org\/10.1016\/j.ejmech.2010.04.022","journal-title":"Eur. J. Med. Chem"},{"key":"8587_CR9","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1039\/D1NJ00132A","volume":"46","author":"N. Satyanarayana","year":"2022","unstructured":"Satyanarayana, N., Sathish, K., Nagaraju, S., Pawar, R., Faizan, M., Arumugavel, M., Shirisha, T., and Kashinath, D., New J. Chem., 2022, vol.\u00a046, pp. 1637\u20131642. https:\/\/doi.org\/10.1039\/D1NJ00132A","journal-title":"New J. Chem"},{"key":"8587_CR10","doi-asserted-by":"publisher","first-page":"103406","DOI":"10.1016\/j.bioorg.2019.103406","volume":"94","author":"K.D. Katariya","year":"2020","unstructured":"Katariya, K.D., Shah, S.R., and Reddy, D., Bioorg. Chem.,\u00a02020, vol. 94, p. 103406. https:\/\/doi.org\/10.1016\/j.bioorg.2019.103406","journal-title":"Bioorg. Chem."},{"key":"8587_CR11","doi-asserted-by":"publisher","first-page":"104968","DOI":"10.1016\/j.bioorg.2021.104968","volume":"112","author":"F. Ran","year":"2021","unstructured":"Ran, F., Liu, Y., Chen, X., Zhuo, H., Xu, C., Li, Y., Duan, X., and Zhao, G., Bioorg. Chem.,\u00a02021, vol. 112, p. 104968. https:\/\/doi.org\/10.1016\/j.bioorg.2021.104968","journal-title":"Bioorg. Chem."},{"key":"8587_CR12","doi-asserted-by":"publisher","first-page":"e22656","DOI":"10.1016\/j.ijcard.2011.06.008","volume":"35","author":"A. Masih","year":"2021","unstructured":"Masih, A., Agnihotri, A.K., Srivastava, J.K., Pandey, N., Bhat, H.R. and Singh, U., J. Biochem. Mol. Toxicol.,\u00a02021 vol. 35, p. e22656. https:\/\/doi.org\/10.1016\/j.ijcard.2011.06.008","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"8587_CR13","doi-asserted-by":"publisher","first-page":"113134","DOI":"10.1016\/j.ejmech.2020.113134","volume":"212","author":"R. Verma","year":"2021","unstructured":"Verma, R., Verma, S.K., Rakesh, K.P., Girish, Y.R., Ashrafizadeh, M., Kumar, K.S.S., and Rangappa, K.S., Eur. J. Med. Chem., 2021, vol.\u00a0212, p. 113134. https:\/\/doi.org\/10.1016\/j.ejmech.2020.113134","journal-title":"Eur. J. Med. Chem"},{"key":"8587_CR14","doi-asserted-by":"publisher","first-page":"104771","DOI":"10.1016\/j.pestbp.2021.104771","volume":"173","author":"Z. Wu","year":"2021","unstructured":"Wu, Z., Yang, W., Hou, S., Xie, D., Yang, J., Liu, L., and Yang, S., Pestic. Biochem. Physiol., 2021, vol.\u00a0173, p. 104771. https:\/\/doi.org\/10.1016\/j.pestbp.2021.104771","journal-title":"Pestic. Biochem. Physiol"},{"key":"8587_CR15","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.ejmech.2017.07.059","volume":"139","author":"Z. Xu","year":"2017","unstructured":"Xu, Z., Gao, C., Ren, Q.C., Song, X.F., Feng, L.S., and Lv, Z.S.,\u00a0Eur. J. Med. Chem., 2017, vol. 139, pp.\u00a0429\u2013440. https:\/\/doi.org\/10.1016\/j.ejmech.2017.07.059","journal-title":"Eur. J. Med. Chem"},{"key":"8587_CR16","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1002\/jhet.3198","volume":"55","author":"S.B. Jadhav","year":"2018","unstructured":"Jadhav, S.B., Fatema, S., Sanap, G., and Farooqui, M.,\u00a0J.\u00a0Heterocycl. Chem., 2018, vol.\u00a055, pp. 1634\u20131644. https:\/\/doi.org\/10.1002\/jhet.3198","journal-title":"J.\u00a0Heterocycl. Chem"},{"key":"8587_CR17","doi-asserted-by":"publisher","first-page":"2","DOI":"10.4103\/0975-7406.171694","volume":"8","author":"M.J. Naim","year":"2016","unstructured":"Naim, M.J., Alam, O., Nawaz, F., Alam, M.J., and Alam, P., J. Pharm. Bioallied Sci., 2016, vol. 8, p. 2. https:\/\/www.jpbsonline.org\/text.asp?2016\/8\/1\/2\/171694","journal-title":"J. Pharm. Bioallied Sci"},{"key":"8587_CR18","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/j.jmgm.2018.02.017","volume":"37","author":"P. Modi","year":"2019","unstructured":"Modi, P., Patel, S., and Chabria, M.T., J. Biomol. Struct. Dyn.,\u00a02019, vol. 37, pp. 1736\u20131749. https:\/\/doi.org\/10.1016\/j.jmgm.2018.02.017","journal-title":"J. Biomol. Struct. Dyn."},{"key":"8587_CR19","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.jfluchem.2016.01.011","volume":"183","author":"N. Nayak","year":"2016","unstructured":"Nayak, N., Ramprasad, J., and Dalimba, U.K., J. Fluor. Chem., 2016, vol. 183, pp. 59\u201368. https:\/\/doi.org\/10.1016\/j.jfluchem.2016.01.011","journal-title":"J. Fluor. Chem."},{"key":"8587_CR20","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1134\/s1070428006070153","volume":"42","author":"V.V. Lipson","year":"2006","unstructured":"Lipson, V.V., Shirobokova, M.G., Shishkin, O.V., and Shishkina, S.V., Russ. J. Org. Chem.,\u00a02006, vol. 42, pp.\u00a01015\u20131021. https:\/\/doi.org\/10.1134\/s1070428006070153","journal-title":"Russ. J. Org. Chem"},{"key":"8587_CR21","doi-asserted-by":"publisher","first-page":"527","DOI":"10.3389\/fchem.2018.00527","volume":"6","author":"M.V. Murlykina","year":"2018","unstructured":"Murlykina, M.V., Morozova, A.D., Zviagin, I.M., Sakhno, Y.I., and Desenko, S.M., Front. Chem.,\u00a02018, vol. 6, p. 527. https:\/\/doi.org\/10.3389\/fchem.2018.00527","journal-title":"Front. Chem"},{"key":"8587_CR22","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1002\/JHET.5570350313","volume":"35","author":"J. Quiroga","year":"1998","unstructured":"Quiroga, J., Insuasty, B., Hormaza, A., Saitz, C., and Jullian, C., J. Heterocycl. Chem.,\u00a01998, vol. 35, pp.\u00a0575\u2013578. https:\/\/doi.org\/10.1002\/JHET.5570350313","journal-title":"J. Heterocycl. Chem."},{"key":"8587_CR23","doi-asserted-by":"publisher","first-page":"181","DOI":"10.3998\/ark.5550190.0008.f18","volume":"15","author":"M.C. Lourenco","year":"2007","unstructured":"Lourenco, M.C., de Souza, M.V., Pinheiro, A.C., Ferreira, M.D.L., Gon\u00e7alves, R.S., Nogueira, T.C.M., and Peralta, M.A., Arkivoc, 2007, vol. 15, pp. 181\u2013191. https:\/\/doi.org\/10.3998\/ark.5550190.0008.f18","journal-title":"Arkivoc"},{"key":"8587_CR24","doi-asserted-by":"publisher","first-page":"181","DOI":"10.3998\/ark.5550190.0008.f18","volume":"15","author":"M.C.S. Louren\u00e7o","year":"2007","unstructured":"Louren\u00e7o, M.C.S., de Souza, M.V.N., Pinheiro, A.C., Ferreira, M. de L., Gon\u00e7alves, R.S.B., Nogueira, T.C.M., and Peralta, M.A., Arkivoc, 2007, vol. 15, pp. 181\u2013191. https:\/\/doi.org\/10.3998\/ark.5550190.0008.f18","journal-title":"Arkivoc"},{"key":"8587_CR25","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1007\/s10870-012-0342-5","volume":"42","author":"W.G. Shuler","year":"2012","unstructured":"Shuler, W.G., Smith, E.A., Hess, S.M., McFadden, T., Metz, C.R., Van Derveer, D.G., and Beam, C.F., J. Chem. Crystallogr., 2012, vol. 42, pp. 952\u2013959. https:\/\/doi.org\/10.1007\/s10870-012-0342-5","journal-title":"J. Chem. Crystallogr"},{"key":"8587_CR26","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1002\/bdrb.20260","volume":"89","author":"J.M. Panzica-Kelly","year":"2010","unstructured":"Panzica-Kelly, J.M., Zhang, C.X., Danberry, T.L., Flood, A., DeLan, J.W., Brannen, K.C., and Augustine-Rauch, K.A., Reprod. Toxicol., 2010, vol. 89, pp.\u00a0382\u2013395. https:\/\/doi.org\/10.1002\/bdrb.20260","journal-title":"Reprod. Toxicol"}],"container-title":["Russian Journal of Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1134\/S1068162023010053.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1134\/S1068162023010053","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1134\/S1068162023010053.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T05:33:08Z","timestamp":1775194388000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1134\/S1068162023010053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,22]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["8587"],"URL":"https:\/\/doi.org\/10.1134\/s1068162023010053","relation":{},"ISSN":["1068-1620","1608-330X"],"issn-type":[{"value":"1068-1620","type":"print"},{"value":"1608-330X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,22]]},"assertion":[{"value":"23 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 September 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflicts of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"COMPLIANCE WITH ETHICAL STANDARDS"}},{"value":"No author of this article conducted any experiments involving humans or animals, and none of the authors conducted any studies that are included in this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"COMPLIANCE WITH ETHICAL STANDARDS"}}]}}