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This article reviews three considerations in support of this restrained approach: rates of spontaneous closure of the ductus arteriosus; adverse effect of persistent ductal patency; and benefits and risks of treatments for closure.<\/jats:p>","DOI":"10.1136\/adc.2005.092734","type":"journal-article","created":{"date-parts":[[2007,10,19]],"date-time":"2007-10-19T15:19:23Z","timestamp":1192807163000},"page":"F498-F502","source":"Crossref","is-referenced-by-count":169,"title":["Patent ductus arteriosus: lack of evidence for common treatments"],"prefix":"10.1136","volume":"92","author":[{"given":"Carl L","family":"Bose","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew M","family":"Laughon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2007,10,19]]},"reference":[{"key":"2025090511052731000_92.6.F498.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.4.659"},{"key":"2025090511052731000_92.6.F498.2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.104.6.1345"},{"key":"2025090511052731000_92.6.F498.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70362-4"},{"key":"2025090511052731000_92.6.F498.4","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200502000-00019"},{"key":"2025090511052731000_92.6.F498.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(96)80123-5"},{"key":"2025090511052731000_92.6.F498.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80719-6"},{"key":"2025090511052731000_92.6.F498.7","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2001.110528"},{"key":"2025090511052731000_92.6.F498.8","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2000.103414"},{"key":"2025090511052731000_92.6.F498.9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1528"},{"key":"2025090511052731000_92.6.F498.10","first-page":"542","article-title":"The natural course of the ductus arteriosus in very low birthweight infants.","volume":"59","author":"Nemerofsky","year":"2006","journal-title":"E-PAS"},{"key":"2025090511052731000_92.6.F498.11","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1164\/ajrccm\/143.2.236","article-title":"Closure of the ductus arteriosus with indomethacin in ventilated neonates with respiratory distress syndrome. 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