{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T05:36:55Z","timestamp":1785908215676,"version":"3.56.0"},"reference-count":56,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p>B-type natriuretic peptide (BNP) and N-terminal-pro-BNP (NTpBNP) have a major role in screening and diagnosis of cardiac disease and monitoring of the treatment response in children and adults. This review discusses the evidence underpinning the potential benefits of these natriuretic peptides in neonatology. They may serve as a useful adjunct to echocardiography in the diagnosis of patent ductus arteriosus and its response to treatment and the diagnosis of persistent pulmonary hypertension of the newborn. However, more work is needed to explore the possible roles of BNP\/NTpBNP in the management of sepsis and monitoring of cardiac performance in neonates.<\/jats:p>","DOI":"10.1136\/adc.2006.106039","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T17:42:19Z","timestamp":1182447739000},"page":"F320-F324","source":"Crossref","is-referenced-by-count":56,"title":["Are B-type natriuretic peptide (BNP) and N-terminal-pro-BNP useful in neonates?"],"prefix":"10.1136","volume":"92","author":[{"given":"Afif","family":"El-Khuffash","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleanor J","family":"Molloy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2007,6,21]]},"reference":[{"key":"2025090221291315000_92.4.F320.1","unstructured":"Vesely DL, Cliffs E. Atrial natriuretic hormones. New Jersey: Prentice Hall, 1992."},{"key":"2025090221291315000_92.4.F320.2","doi-asserted-by":"publisher","DOI":"10.1038\/332078a0"},{"key":"2025090221291315000_92.4.F320.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(89)80056-7"},{"key":"2025090221291315000_92.4.F320.4","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1161\/01.CIR.90.3.1129","volume":"90","year":"1994","journal-title":"Circulation"},{"key":"2025090221291315000_92.4.F320.5","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000232322.06633.d3"},{"key":"2025090221291315000_92.4.F320.6","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1995.2410"},{"key":"2025090221291315000_92.4.F320.7","doi-asserted-by":"publisher","DOI":"10.1186\/cc2890"},{"key":"2025090221291315000_92.4.F320.8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0525"},{"key":"2025090221291315000_92.4.F320.9","first-page":"2875","volume":"59","year":"2006","journal-title":"E-PAS"},{"key":"2025090221291315000_92.4.F320.10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.54.030192.000303"},{"key":"2025090221291315000_92.4.F320.11","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2004.037762"},{"key":"2025090221291315000_92.4.F320.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2005.11.005"},{"key":"2025090221291315000_92.4.F320.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-8981(01)00578-2"},{"key":"2025090221291315000_92.4.F320.14","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.2002.2005"},{"key":"2025090221291315000_92.4.F320.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2004.04.004"},{"key":"2025090221291315000_92.4.F320.16","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000130846.46168.03"},{"key":"2025090221291315000_92.4.F320.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02060-2"},{"key":"2025090221291315000_92.4.F320.18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000054164.99881.00"},{"key":"2025090221291315000_92.4.F320.19","doi-asserted-by":"publisher","DOI":"10.1080\/08035250410022756"},{"key":"2025090221291315000_92.4.F320.20","doi-asserted-by":"publisher","DOI":"10.1080\/08035250410025799"},{"key":"2025090221291315000_92.4.F320.21","doi-asserted-by":"publisher","DOI":"10.1080\/08035250500466647"},{"key":"2025090221291315000_92.4.F320.22","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi773"},{"key":"2025090221291315000_92.4.F320.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2006.02.038"},{"key":"2025090221291315000_92.4.F320.24","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-005-1027-z"},{"key":"2025090221291315000_92.4.F320.25","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1429"},{"key":"2025090221291315000_92.4.F320.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.10.039"},{"key":"2025090221291315000_92.4.F320.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.01.022"},{"key":"2025090221291315000_92.4.F320.28","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1111\/j.1399-3046.2005.00365.x","volume":"9","year":"2005","journal-title":"Pediatr Transplant"},{"key":"2025090221291315000_92.4.F320.29","first-page":"336","volume":"25","year":"2004","journal-title":"Pediatr Cardiol"},{"key":"2025090221291315000_92.4.F320.30","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi236"},{"key":"2025090221291315000_92.4.F320.31","first-page":"2872","volume":"109","year":"2005","journal-title":"Circulation"},{"key":"2025090221291315000_92.4.F320.32","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.6.e76"},{"key":"2025090221291315000_92.4.F320.33","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.4.896"},{"key":"2025090221291315000_92.4.F320.34","doi-asserted-by":"publisher","DOI":"10.1016\/0033-0620(72)90006-0"},{"key":"2025090221291315000_92.4.F320.35","first-page":"913","volume":"51","year":"2003","journal-title":"Semin Neonatol"},{"key":"2025090221291315000_92.4.F320.36","doi-asserted-by":"publisher","DOI":"10.1136\/heart.89.8.875"},{"key":"2025090221291315000_92.4.F320.37","first-page":"191","volume":"57","year":"2003","journal-title":"Acta Med Okayama"},{"key":"2025090221291315000_92.4.F320.38","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2005.048892"},{"key":"2025090221291315000_92.4.F320.39","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-005-0246-x"},{"key":"2025090221291315000_92.4.F320.40","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2004.046557"},{"key":"2025090221291315000_92.4.F320.41","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2004.040253"},{"key":"2025090221291315000_92.4.F320.42","doi-asserted-by":"publisher","DOI":"10.1373\/49.9.1563"},{"key":"2025090221291315000_92.4.F320.43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2005.03.040"},{"key":"2025090221291315000_92.4.F320.44","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-1837"},{"key":"2025090221291315000_92.4.F320.45","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1042\/cs1030079","volume":"103","year":"2002","journal-title":"Clin Sci (Lond)"},{"key":"2025090221291315000_92.4.F320.46","doi-asserted-by":"publisher","DOI":"10.1080\/080352501300049406"},{"key":"2025090221291315000_92.4.F320.47","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211383"},{"key":"2025090221291315000_92.4.F320.48","first-page":"3875","volume":"59","year":"2006","journal-title":"Pediatr Res"},{"key":"2025090221291315000_92.4.F320.49","first-page":"556","volume":"59","year":"2006","journal-title":"Pediatr Res"},{"key":"2025090221291315000_92.4.F320.50","first-page":"341","volume":"25","year":"2004","journal-title":"Pediatr Cardiol"},{"key":"2025090221291315000_92.4.F320.51","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-003-1910-0"},{"key":"2025090221291315000_92.4.F320.52","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000229144.97624.90"},{"key":"2025090221291315000_92.4.F320.53","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000226266.99960.d0"},{"key":"2025090221291315000_92.4.F320.54","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.472050"},{"key":"2025090221291315000_92.4.F320.55","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000162561.82012.E9"},{"key":"2025090221291315000_92.4.F320.56","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0569"}],"container-title":["Archives of Disease in Childhood - Fetal and Neonatal Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/adc.2006.106039","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T04:29:27Z","timestamp":1756873767000},"score":1,"resource":{"primary":{"URL":"https:\/\/fn.bmj.com\/lookup\/doi\/10.1136\/adc.2006.106039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,21]]},"references-count":56,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2007,6,21]]},"published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1136\/adc.2006.106039"],"URL":"https:\/\/doi.org\/10.1136\/adc.2006.106039","relation":{},"ISSN":["1359-2998","1468-2052"],"issn-type":[{"value":"1359-2998","type":"print"},{"value":"1468-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,21]]}}}