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Assessments of the efficacy of respiratory efforts and hence the balance of respiratory drive, muscle performance and respiratory load appear to best predict weaning and extubation success. Essential to the success of weaning and extubation are dedicated staff, whether this will be assisted by computerised decision-making tools requires testing. The above approaches are not mutually exclusive and those indicated by this review as appropriately evidence based should be considered by practitioners for current use to reduce difficult\/unsuccessful extubation.<\/jats:p>","DOI":"10.1136\/adc.2007.121335","type":"journal-article","created":{"date-parts":[[2007,11,15]],"date-time":"2007-11-15T20:45:09Z","timestamp":1195159509000},"page":"F242-F245","source":"Crossref","is-referenced-by-count":16,"title":["Difficult extubation in low birthweight infants"],"prefix":"10.1136","volume":"93","author":[{"given":"A","family":"Greenough","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Prendergast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2007,11,15]]},"reference":[{"key":"2025090510224032000_93.3.F242.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020432"},{"key":"2025090510224032000_93.3.F242.2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2002.121381"},{"key":"2025090510224032000_93.3.F242.3","doi-asserted-by":"crossref","unstructured":"Greenough A Milner AD Dimitriou G . 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