{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:48:55Z","timestamp":1759564135985,"version":"3.44.0"},"reference-count":23,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives:<\/jats:title>\n                  <jats:p>To investigate prognosis of the fetus with isolated gastroschisis and bowel dilatation from a systematic review of the literature. We aimed to compare the incidence of (a) intrauterine death, (b) death within 4 weeks of delivery, (c) bowel resection, (d) length of time to oral feeds and (e) time as inpatient in fetuses with gastroschisis with and without evidence of bowel dilatation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>Literature was identified by searching two bibliographical databases between 1980 and 2007. Studies were assessed for quality and stratified according to the definition of bowel dilatation. The data extracted were inspected for clinical and methodological heterogeneity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>The search strategy yielded 1335 potentially relevant citations. Full manuscripts were retrieved for 92 citations. 10 studies (273 patients) were finally included in the systematic review. No difference was found between groups for death within 4 weeks of delivery (OR\u200a=\u200a0.62 (95% CI 0.11 to 3.32); heterogeneity p\u200a=\u200a0.39) or bowel resection (OR\u200a=\u200a3.35 (95% CI 0.82 to 13.74); heterogeneity p\u200a=\u200a0.39). There were insufficient data to compare the risk of intrauterine death and length of time to oral feeds. The mean inpatient stay was not significantly different between groups (OR\u200a=\u200a16.63 (95% CI 0.98 to 32.28); heterogeneity p\u200a=\u200a0.23).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>Current available evidence suggests that fetuses with isolated gastroschisis and bowel dilatation are not at increased risk of adverse perinatal outcome compared to those without bowel dilatation. However, there is a paucity of studies, and a randomised controlled trial is urgently needed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/adc.2008.140434","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T20:25:26Z","timestamp":1226348726000},"page":"F268-F274","source":"Crossref","is-referenced-by-count":37,"title":["Prognosis in isolated gastroschisis with bowel dilatation: a systematic review"],"prefix":"10.1136","volume":"94","author":[{"given":"C","family":"Tower","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S C","family":"Ong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A K","family":"Ewer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M D","family":"Kilby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2008,11,10]]},"reference":[{"key":"2025090514280107000_94.4.F268.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7536.250"},{"key":"2025090514280107000_94.4.F268.2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2003.047902"},{"key":"2025090514280107000_94.4.F268.3","unstructured":"Donaldson L . Gastroschisis: a growing concern. London: Department of Health, 2004."},{"key":"2025090514280107000_94.4.F268.4","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1097\/01.AOG.0000139513.93115.81","article-title":"Mode of delivery and neonatal survival of infants with isolated gastroschisis.","volume":"104","author":"Salihu","year":"2004","journal-title":"Obstet Gynecol"},{"key":"2025090514280107000_94.4.F268.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(88)80360-9"},{"key":"2025090514280107000_94.4.F268.6","doi-asserted-by":"publisher","DOI":"10.1002\/uog.85"},{"key":"2025090514280107000_94.4.F268.7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"2025090514280107000_94.4.F268.8","unstructured":"Khan K Riet GT Glanville J . Undertaking systematic reviews of research on effectiveness. CRD\u2019s guidance for carrying out or commissioning reviews. 2nd ed. York: NHS Centre for Reviews and Dissemination, University of York, 2000."},{"key":"2025090514280107000_94.4.F268.9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.1.89"},{"key":"2025090514280107000_94.4.F268.10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6965.1351"},{"key":"2025090514280107000_94.4.F268.11","doi-asserted-by":"crossref","unstructured":"Deeks JJ Altman DG Bradburn MJ . Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Egger M Davey Smith G Altman D G , eds. Systematic reviews in health care: meta-analysis in context. London: BMJ Books, 2001:285\u2013312.","DOI":"10.1002\/9780470693926.ch15"},{"key":"2025090514280107000_94.4.F268.12","first-page":"53","article-title":"Prenatal diagnosis of gastroschisis: development of objective sonographic criteria for predicting outcome.","volume":"81","author":"Langer","year":"1993","journal-title":"Obstet Gynecol"},{"key":"2025090514280107000_94.4.F268.13","first-page":"505","article-title":"Gastroschisis: can antenatal ultrasound predict infant outcomes?","volume":"84","author":"Pryde","year":"1994","journal-title":"Obstet Gynecol"},{"key":"2025090514280107000_94.4.F268.14","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/0002-9378(90)91111-O","article-title":"Ultrasonographic assessment of intestinal damage in fetuses with gastroschisis: is it of clinical value?","volume":"163","author":"Lenke","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"2025090514280107000_94.4.F268.15","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/j.1471-0528.1992.tb14438.x","article-title":"The importance of serial biophysical assessment of fetal wellbeing in gastroschisis.","volume":"99","author":"Crawford","year":"1992","journal-title":"Br J Obstet Gynaecol"},{"key":"2025090514280107000_94.4.F268.16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1996.tb01212.x"},{"key":"2025090514280107000_94.4.F268.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.01.005"},{"key":"2025090514280107000_94.4.F268.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70424-6"},{"key":"2025090514280107000_94.4.F268.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)80037-8"},{"key":"2025090514280107000_94.4.F268.20","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-007-2004-9"},{"key":"2025090514280107000_94.4.F268.21","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e3282ffdc1e"},{"key":"2025090514280107000_94.4.F268.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.09.049"},{"key":"2025090514280107000_94.4.F268.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.04.032"}],"container-title":["Archives of Disease in Childhood - Fetal and Neonatal Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/adc.2008.140434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T21:28:09Z","timestamp":1757107689000},"score":1,"resource":{"primary":{"URL":"https:\/\/fn.bmj.com\/lookup\/doi\/10.1136\/adc.2008.140434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,10]]},"references-count":23,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2009,6,19]]},"published-print":{"date-parts":[[2009,7]]}},"alternative-id":["10.1136\/adc.2008.140434"],"URL":"https:\/\/doi.org\/10.1136\/adc.2008.140434","relation":{},"ISSN":["1359-2998","1468-2052"],"issn-type":[{"type":"print","value":"1359-2998"},{"type":"electronic","value":"1468-2052"}],"subject":[],"published":{"date-parts":[[2008,11,10]]}}}