{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T19:30:42Z","timestamp":1787599842221,"version":"build-2736575974"},"reference-count":5,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"accepted":{"date-parts":[[2010,5,20]]},"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>It is widely accepted that maternal drug-exposed infants demonstrate excessive early weight loss, but this has not previously been quantified. Among 354 term, substitute methadone-exposed infants, median maximal weight losses were 10.2% and 8.5% for breast- and formula-fed infants, respectively (p=0.003). Weight loss was less in small for gestational age compared to appropriately grown infants (p&lt;0.001). There was no association between maximal weight loss and plasma sodium concentration (p=0.807). Relative to non-drug exposed infants, weight loss was more marked in formula-fed infants, 48% of whom demonstrated weight loss in excess of the 95th centile (compared to 23% of exclusively breastfed infants; p&lt;0.001). Median weight loss nadir was on day 5, excepting those infants exclusively breastfed (day 4). These data suggest that excessive neonatal weight loss among breastfed infants of drug-misusing mothers does not necessarily reflect poorly established lactation and may help to guide management of breast feeding in this population.<\/jats:p>","DOI":"10.1136\/adc.2009.178723","type":"journal-article","created":{"date-parts":[[2010,7,23]],"date-time":"2010-07-23T20:32:19Z","timestamp":1279917139000},"page":"F214-F216","source":"Crossref","is-referenced-by-count":30,"title":["Postnatal weight loss in substitute methadone-exposed infants: implications for the management of breast feeding"],"prefix":"10.1136","volume":"97","author":[{"given":"Carol","family":"Dryden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Mactier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2010,7,23]]},"reference":[{"key":"2025090511390780000_97.3.F214.1","unstructured":"About Kids Health. Pregnancy & babies. http:\/\/www.aboutkidshealth.ca\/Pregnancy\/Neonatal-Abstinence-Syndrome.aspx?articleID=9541&categoryID=PG-nh2-09o (Accessed 22 March 2010)."},{"key":"2025090511390780000_97.3.F214.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.02073.x"},{"key":"2025090511390780000_97.3.F214.3","doi-asserted-by":"publisher","DOI":"10.1177\/000992287501400613"},{"key":"2025090511390780000_97.3.F214.4","doi-asserted-by":"publisher","DOI":"10.1136\/fn.88.6.F472"},{"key":"2025090511390780000_97.3.F214.5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.2002.00724.x"}],"container-title":["Archives of Disease in Childhood - Fetal and Neonatal Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/adc.2009.178723","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T18:57:27Z","timestamp":1757098647000},"score":1,"resource":{"primary":{"URL":"https:\/\/fn.bmj.com\/lookup\/doi\/10.1136\/adc.2009.178723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,23]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012,4,17]]},"published-print":{"date-parts":[[2012,5]]}},"alternative-id":["10.1136\/adc.2009.178723"],"URL":"https:\/\/doi.org\/10.1136\/adc.2009.178723","relation":{},"ISSN":["1359-2998","1468-2052"],"issn-type":[{"value":"1359-2998","type":"print"},{"value":"1468-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,23]]}}}