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This was found to be in the region of the corpus callosum, the septum pelucidum, fomix, and related regions of the lateral ventricles. A survey carried out of 200 brains of children dying in the postperinatal period indicated that the fatty change is principally related to two groups of children-early perinatal deaths associated with severe hypoxia and a number of the unexplained, unexpected deaths in infancy. Evidence was presented which indicated that this fatty change is pathological and suggests that it is a reaction to hypoxia in actively myelinating brain tissue."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/jcp.24.8.753","article-title":"Fat-laden macrophages in cerebrospinal fluid as an indication of brain damage in children","volume":"24","author":"Chester, D.C.; Emery, J.L.; Penny, S.R.","year":"1971","unstructured":"Chester, D. C., Emery, J. L., and Penny, S. R. (1971). Fat-laden macrophages in cerebrospinal fluid as an indication of brain damage in children. Journal of Clinical Pathology, 24, 753.","journal-title":"Journal of Clinical Pathology"},{"key":"ref_5","first-page":"33","article-title":"Fat-contaimng macrophages in the cerebrospinal fluid of children with hydrocephalus","volume":"25","author":"Chester, D.C.; Penny, S.R.; Emery, J.L.","year":"1971","unstructured":"Chester, D. C., Penny, S. R., and Emery, J. L. (1971). Fat-contaimng macrophages in the cerebrospinal fluid of children with hydrocephalus. 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