{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T21:38:34Z","timestamp":1699565914120},"reference-count":18,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Disease in Childhood"],"published-print":{"date-parts":[[1978,5,1]]},"DOI":"10.1136\/adc.53.5.424","type":"journal-article","created":{"date-parts":[[2008,12,22]],"date-time":"2008-12-22T21:33:49Z","timestamp":1229981629000},"page":"424-426","source":"Crossref","is-referenced-by-count":14,"title":["Pulmonary interstitial emphysema requiring lobectomy. 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M., and Unger, R. H. (1969). Effects of starvation on plasma pancreatic glucagon in normal man. Diabetes, 18, 717-723.","journal-title":"Diabetes"},{"key":"ref_2","article-title":"Disorders of Carbohydrate Metabolism in Infancy","author":"Cornblath, M.; Schwartz, R.","year":"1976","unstructured":"Cornblath, M., and Schwartz, R. (1976). Disorders of Carbohydrate Metabolism in Infancy. Saunders, Philadelphia."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/S0140-6736(70)91946-X","article-title":"Neonatal hypoglycaemia, hyperinsulinism and absence of pancreatic alpha cells","volume":"1","author":"Gotlin, R.W.; Silver, H.K.","year":"1970","unstructured":"Gotlin, R. W., and Silver, H. K. (1970). Neonatal hypoglycaemia, hyperinsulinism and absence of pancreatic alpha cells. Lancet, 1, 1346.","journal-title":"Lancet"},{"key":"ref_4","first-page":"337","article-title":"Deficiency of alpha cells of pancreas as possible etiologic factor in familial hypoglycemosis","volume":"9","author":"McQuarrie, I.; Bell, E.T.; Zimmerman, B.; Wright, W.S.","year":"1950","unstructured":"McQuarrie, I., Bell, E. T., Zimmerman, B., and Wright, W. S. (1950). Deficiency of alpha cells of pancreas as possible etiologic factor in familial hypoglycemosis. (Abst.) Federation Proceedings, 9, 337.","journal-title":"(Abst.) Federation Proceedings"},{"key":"ref_5","first-page":"778826","article-title":"Physiology and pathophysiology of glucagon","volume":"56","author":"Unger, R.H.; Orci, L.","year":"1976","unstructured":"Unger, R. H., and Orci, L. (1976). Physiology and pathophysiology of glucagon. Physiological Reviews, 56, 778826.","journal-title":"Physiological Reviews"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1203\/00006450-197610000-00057","article-title":"Persistent hereditary neonatal hypoglycaemia caused by glucagon deficiency","volume":"10","author":"Vidnes, J.","year":"1976","unstructured":"Vidnes, J. (1976). Persistent hereditary neonatal hypoglycaemia caused by glucagon deficiency. (Abst.) Pediatric Research, 10, 881.","journal-title":"(Abst.) Pediatric Research"},{"key":"ref_7","article-title":"Kongenitaler alpha-Zellmangel als Ursache einer chronischen infantillen Hypoglykamie? Monatsschrift fdr Kinderheil","author":"Wagner, T.; Spranger, J.; Brunck, H.J.","year":"1969","unstructured":"Wagner, T., Spranger, J., and Brunck, H. J. (1969). Kongenitaler alpha-Zellmangel als Ursache einer chronischen infantillen Hypoglykamie? Monatsschrift fdr Kinderheil."},{"key":"ref_8","article-title":"resolves spontaneously. In some cases the interstitial pulmonary air dissects along peribronchial and perivascular spaces leading to pneumomediastinum or pneumothorax","volume-title":"Pulmonary interstitial emphysema has been increasingly reported following IPPV","author":"(Fletcher et al.,","year":"1973","unstructured":"resolves spontaneously. In some cases the interstitial pulmonary air dissects along peribronchial and perivascular spaces leading to pneumomediastinum or pneumothorax (Thibeault et al., 1973). Pulmonary interstitial emphysema has been increasingly reported following IPPV (Fletcher et al., 1974). Our case is unusual as the interstitial emphysema was localised to one lobe and progressed to develop tension causing mediastinal shift to the opposite side and compression of the contralateral lung. The lesion was unilateral from the start and followed collapse of the affected lobe. Presumably, ball-valve obstruction led to alveolar rupture, with dissection of air into extraalveolar spaces, then into the interlobular septa, and possibly into the peribronchial lymphatics. Possibly endotracheal aspiration and\/or the insertion of a needle blind into the thoracic cavity were factors in our case."},{"key":"ref_9","first-page":"776","article-title":"Other conditions must be considered in the differential diagnosis. Congenital lobar emphysema is usually associated with demonstrable flaccidity of bronchi of which the commonest cause is cartilage deficiency. In our case the cartilage content of the bronchi was normal and the collapsed lung separated by large cysts differed completely from the overdistended alveoli of emphysema. Congenital cystic Conservative management of unilateral pulmonary interstitial emphysema under tension","volume":"87","unstructured":"Other conditions must be considered in the differential diagnosis. Congenital lobar emphysema is usually associated with demonstrable flaccidity of bronchi of which the commonest cause is cartilage deficiency. In our case the cartilage content of the bronchi was normal and the collapsed lung separated by large cysts differed completely from the overdistended alveoli of emphysema. Congenital cystic Conservative management of unilateral pulmonary interstitial emphysema under tension. Journal of Pediatrics, 87, 776-778.","journal-title":"Journal of Pediatrics"},{"key":"ref_10","first-page":"516","article-title":"Changing prognosis for infants of very low lung was excluded by the complete preservation of birthweight","volume":"1","year":"1971","unstructured":"Rawlings, G., Stewart, A., Reynolds, E. 0. R., and Strang, L. B. (1971). Changing prognosis for infants of very low lung was excluded by the complete preservation of birthweight. Lancet, 1, 516-519.","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/oxfordjournals.bmb.a071235","article-title":"Management of hyaline membrane disease","volume":"31","author":"Reynolds, E. 0. R","year":"1975","unstructured":"Reynolds, E. 0. R. (1975). Management of hyaline membrane disease. British Medical Bulletin, 31, 18-24.","journal-title":"British Medical Bulletin"},{"key":"ref_12","article-title":"Treatment of cystic ventilator lung disease","volume":"69","author":"Roberton, N.R.","year":"1976","unstructured":"Roberton, N. R. (1976). Treatment of cystic ventilator lung disease. Proceedings of the Royal Society of Medicine, 69, lobular connective tissue regions.","journal-title":"Proceedings of the Royal Society of Medicine; lobular connective tissue regions"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1001\/archpedi.1973.02110190493005","article-title":"Pulmonary interstitial emphysema, pneumomediastinum and pneumothorax","volume":"126","author":"Thibeault, D.W.; Lachman, R.S.; Laul, V.R.; Kwong, M.S.","year":"1973","unstructured":"Thibeault, D. W., Lachman, R. S., Laul, V. R., and Kwong, M. S. (1973). Pulmonary interstitial emphysema, pneumomediastinum and pneumothorax. American Journal of Diseases of Children, 126, 611-614.","journal-title":"American Journal of Diseases of Children"},{"key":"ref_14","article-title":"vigorous therapy with tracheobronchial suction along","author":"with vibration; and percussion (Leonidas","year":"1975","unstructured":"vigorous therapy with tracheobronchial suction along with vibration and percussion (Leonidas et al., 1975). Roberton (1976) used an Argyle thoracentesis catheter to aspirate from the centre of the cystic area. Infantile cortical hyperostosis with Brooks et al. (1976) reported the successful use of selective bronchial intubation in 4 premature infants.","journal-title":"Brooks et al; used an Argyle thoracentesis catheter to aspirate from the centre of the cystic area. Infantile cortical hyperostosis with"},{"key":"ref_15","article-title":"is characterised by fever, irritability, swelling of the soft tissues, and cortical hyperostosis of the Summary underlying bones. The disease usually occurs before","volume-title":"In most cases there is complete An infant with hyaline membrane disease treated recovery, though recurrences and crippling deformiwith intermittent positive pressure ventilation ties have been reported","year":"1975","unstructured":") is characterised by fever, irritability, swelling of the soft tissues, and cortical hyperostosis of the Summary underlying bones. The disease usually occurs before the fifth month of life. In most cases there is complete An infant with hyaline membrane disease treated recovery, though recurrences and crippling deformiwith intermittent positive pressure ventilation ties have been reported (Blank, 1975). The cause developed pulmonary interstitial emphysema locaremains unknown. We report 2 cases, both with lised to one lobe after collapse of the affected lobe. raised immunoglobulins."},{"key":"ref_16","article-title":"Selective bronchial intubation for the treatment of severe localized interstitial emphysema","author":"Brooks, J.G.; Koops, B.L.; Hilton, S.; Wesenberg, R.L.; Simmons, M.A.","year":"1976","unstructured":"Brooks, J. G., Koops, B. L., Hilton, S., Wesenberg, R. L., and Simmons, M. A. (1976). Selective bronchial intubation for the treatment of severe localized interstitial emphysema."},{"issue":"808-8","key":"ref_17","first-page":"10","article-title":"Pulmonary interstitial emphysema in a newborn infant treated by lobectomy","volume":"54","author":"Fletcher, B.D.; Outerbridge, E.W.; Youssef, S.; Bolande, R.P.","year":"1974","unstructured":"Fletcher, B. D., Outerbridge, E. W., Youssef, S., and Bolande, R. P. (1974). Pulmonary interstitial emphysema in a newborn infant treated by lobectomy. Pediatrics, 54, 808-8 10.","journal-title":"Pediatrics"},{"key":"ref_18","author":"Leonidas, J.C.; Hall, R.T.; Rhodes, P.G.","year":"1975","unstructured":"Leonidas, J. C., Hall, R. T., and Rhodes, P. G. 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