{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:16:11Z","timestamp":1761488171800},"reference-count":8,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Disease in Childhood"],"published-print":{"date-parts":[[1984,5,1]]},"DOI":"10.1136\/adc.59.5.477","type":"journal-article","created":{"date-parts":[[2008,12,22]],"date-time":"2008-12-22T21:51:33Z","timestamp":1229982693000},"page":"477-479","source":"Crossref","is-referenced-by-count":4,"title":["Severe ornithine transcarbamylase deficiency. Two and a half years' survival with normal development."],"prefix":"10.1136","volume":"59","author":[{"given":"P","family":"Guibaud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Baxter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Bourgeois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J J","family":"Louis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Bureau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"issue":"8","key":"ref_1","first-page":"1","article-title":"Changing composition of milk and carly devclopmcnt of appetitc","volume":"779","author":"Hall, B.","year":"1975","unstructured":"Hall B. Changing composition of milk and carly devclopmcnt of appetitc. Lancet 1975 i:779-8 1.","journal-title":"Lancet"},{"key":"ref_2","article-title":"A boy born in June 1981, the fourth child of unrelated French parents, was transferred to this hospital aged 3 days. His brothers had died as neonates-two from congenital malformations with no hyperammonaemia and one from ornithine transcarbamylase deficiency. His mother is asymptomatic but her serum ammonia and urine orotic acid concentrations rose abnormally on protein challenge. Jejunal biopsies in both parents showed normal ornithine transcarbamylase activity","unstructured":"A boy born in June 1981, the fourth child of unrelated French parents, was transferred to this hospital aged 3 days. His brothers had died as neonates-two from congenital malformations with no hyperammonaemia and one from ornithine transcarbamylase deficiency. His mother is asymptomatic but her serum ammonia and urine orotic acid concentrations rose abnormally on protein challenge. Jejunal biopsies in both parents showed normal ornithine transcarbamylase activity."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1056\/NEJM198206103062303","article-title":"Treatment of inborn errors of urea synthesis","volume":"306","author":"Batshaw, M.L.; Brusilow, S.W.; Wager, L.","year":"1982","unstructured":"Batshaw ML, Brusilow SW, Wager L, et al. Treatment of inborn errors of urea synthesis. N Engl J Med 1982;306:1387-92.","journal-title":"N Engl J Med"},{"key":"ref_4","first-page":"1","article-title":"Ornithine transcarbamylase deficiency: long term survival","volume":"21","author":"Michel, VV, Potts; E, Walser; M, Beaudet; A.L.","year":"1982","unstructured":"Michel VV, Potts E, Walser M, Beaudet AL. Ornithine transcarbamylase deficiency: long term survival. 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In: Stanbury JB, Wyngaardcn JB1 Fredrickson DS, eds. The metabolic basis of inherited disease. 4th ed. New York: MacGraw Hill, 1978:362-86.","edition":"4th ed"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0022-3476(78)81149-4","article-title":"Treatment of complete ornithine transcarbamylase deficiency with nitrogen-free analogues of essential amino-acids","volume":"93","author":"McReynolds, J.W.; Montagos, S.; Brusilow, S.; Rosenberg, L.E.","year":"1978","unstructured":"McReynolds JW, Montagos S, Brusilow S, Rosenberg LE. Treatment of complete ornithine transcarbamylase deficiency with nitrogen-free analogues of essential amino-acids. 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