{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T20:09:41Z","timestamp":1649189381801},"reference-count":8,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Disease in Childhood"],"published-print":{"date-parts":[[1988,6,1]]},"DOI":"10.1136\/adc.63.6.684","type":"journal-article","created":{"date-parts":[[2008,12,22]],"date-time":"2008-12-22T22:13:07Z","timestamp":1229983987000},"page":"684-684","source":"Crossref","is-referenced-by-count":0,"title":["Marfan's syndrome in mitral valve disease."],"prefix":"10.1136","volume":"63","author":[{"given":"T","family":"Geva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Frand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"96","article-title":"Mitral valvc disease in Marfan's syndrome","volume":"62","author":"Marlow, N.; Gregg, J.E.M.; Oureshi, S.A.","year":"1987","unstructured":"Marlow N, Gregg JEM, Oureshi SA. Mitral valvc disease in Marfan's syndrome. Arch Dis Clhild 1987;62:96t-2.","journal-title":"Arch Dis Clhild"},{"issue":"1","key":"ref_2","first-page":"179","article-title":"The clinical coursc aind echocardiographic features of Marfan's syndrome in childhood","volume":"141","author":"Geva, T.; fHegesh J; Frand, M.","year":"1987","unstructured":"Geva T, fHegesh J, Frand M. The clinical coursc aind echocardiographic features of Marfan's syndrome in childhood. Ain J Dis Chiild 1987; 141:1 179-82.","journal-title":"Ain J Dis Chiild"},{"key":"ref_3","first-page":"35","article-title":"The Marfan's syndrome in early childhood: analysis of 15 paticnts at Icss thain 4 years of age","volume":"52","author":"Sisk, H.E.; Zahka, K.G.; Pyeritz, R.E.","year":"1983","unstructured":"Sisk HE, Zahka KG, Pyeritz RE. The Marfan's syndrome in early childhood: analysis of 15 paticnts at Icss thain 4 years of age. Am J Cardiol 1983;52:35.3-8.","journal-title":"Am J Cardiol"},{"key":"ref_4","article-title":"Tel Hashomer 52621 and Sackler School of Medicine, Tel A viv University, Israel senior house officers, often with no prcvious pacdiatric expericnce, on a 1: 2 rota, without any intermediate cover. to cover general and neonatal wards including labour ward resuscitation. We do not therefore have a 1: 3 rota. nor a 'safety net'. Five years of local discussions have not altered this. What is needed is a unitcd and forceful voice from the British Paediatric Association nationally, coupled with specific advice for consultant paediatricians on how to get past the embargoes on incrcasing junior staff","author":"GEVA, T.; of Pediatrics C, M.Frand Department; Center, The Chaim Sheba Medical","unstructured":"T GEVA and M Frand Department of Pediatrics C, The Chaim Sheba Medical Center, Tel Hashomer 52621 and Sackler School of Medicine, Tel A viv University, Israel senior house officers, often with no prcvious pacdiatric expericnce, on a 1:2 rota, without any intermediate cover. to cover general and neonatal wards including labour ward resuscitation. We do not therefore have a 1:3 rota. nor a 'safety net'. Five years of local discussions have not altered this. What is needed is a unitcd and forceful voice from the British Paediatric Association nationally, coupled with specific advice for consultant paediatricians on how to get past the embargoes on incrcasing junior staff."},{"issue":"63","key":"ref_5","first-page":"96","article-title":"Medicail stalffinlgl in paediatric dcpartmicrnts in district general hospitals","volume":"1988","author":"Ncison, R.","unstructured":"Ncison R. Medicail stalffinlgl in paediatric dcpartmicrnts in district general hospitals. Arr\/ l)is Child 1988:63:96-7.","journal-title":"Arr\/ l)is Child"},{"key":"ref_6","article-title":"AlRoomi et al used phenobarbitone and chloral as first line drugs for the treatment of symptoms, but they make no comment on the effectiveness of these agents. In our series 15 (40%) babies also developed withdrawal signs but our initial experience with phenobarbitone by injection was disappointing. We subsequently tricd oral chlorpromazinc, which we stopped using because of its epileptogenic potential, although it was effective. We now consider that treatment with pure aqueous morphine sulphate (0. 125 mg) given orally and as required is pharmacologically appropriate, have found it effective, and would recommend its use","unstructured":"AlRoomi et al used phenobarbitone and chloral as first line drugs for the treatment of symptoms, but they make no comment on the effectiveness of these agents. In our series 15 (40%) babies also developed withdrawal signs but our initial experience with phenobarbitone by injection was disappointing. We subsequently tricd oral chlorpromazinc, which we stopped using because of its epileptogenic potential, although it was effective. We now consider that treatment with pure aqueous morphine sulphate (0. 125 mg) given orally and as required is pharmacologically appropriate, have found it effective, and would recommend its use."},{"key":"ref_7","article-title":"In our series only eight (22%) children were subject to legal constraints, compared with 38% in AlRoomi's series. While this may simply reflect a different approach to social management, it may be that heroin abuse by inhalation has less disruptive effects on family life","unstructured":"In our series only eight (22%) children were subject to legal constraints, compared with 38% in AlRoomi's series. While this may simply reflect a different approach to social management, it may be that heroin abuse by inhalation has less disruptive effects on family life."},{"key":"ref_8","article-title":"We also found that these children were not brought to hospital for follow up appointments. We now consider that community based surveillance is more appropriate","unstructured":"We also found that these children were not brought to hospital for follow up appointments. We now consider that community based surveillance is more appropriate."}],"container-title":["Archives of Disease in Childhood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/adc.63.6.684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T00:01:37Z","timestamp":1601078497000},"score":1,"resource":{"primary":{"URL":"https:\/\/adc.bmj.com\/lookup\/doi\/10.1136\/adc.63.6.684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6,1]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1988,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/adc.63.6.684","relation":{},"ISSN":["0003-9888","1468-2044"],"issn-type":[{"value":"0003-9888","type":"print"},{"value":"1468-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,6,1]]}}}