{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:06:15Z","timestamp":1761743175533},"reference-count":12,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Disease in Childhood"],"published-print":{"date-parts":[[1989,8,1]]},"DOI":"10.1136\/adc.64.8.1204","type":"journal-article","created":{"date-parts":[[2008,12,22]],"date-time":"2008-12-22T22:13:07Z","timestamp":1229983987000},"page":"1204-1206","source":"Crossref","is-referenced-by-count":23,"title":["Lichen sclerosus."],"prefix":"10.1136","volume":"64","author":[{"given":"J","family":"Berth-Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R A","family":"Graham-Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Burns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"1404","article-title":"They reported complete disappearance of symptoms in a quarter of their cases, within one year of follow up, and a further half of their patients were improved at one and a half years. More recently, however, Ridley stated that she had never seen a case spontaneously resolve.9 We have never observed complete resolution either, although many of our cases have improved to the point where they are asymptomatic. Extra-genital disease seems to carry the best prognosis. 4 17 Complete resolution in adults is rare, and probably confined to extragenital lesions.4 In adult lichen sclerosus carcinoma may supervene,4 and although this complication has not been reported in childhood, Wallace recorded a case in whom carcinoma developed at the age of30 in a patient who had suffered persistent lichen sclerosus since childhood.4 sus et atrophicus in children misdiagnosed as sexual abuse","volume":"294","year":"1987","unstructured":"They reported complete disappearance of symptoms in a quarter of their cases, within one year of follow up, and a further half of their patients were improved at one and a half years. More recently, however, Ridley stated that she had never seen a case spontaneously resolve.9 We have never observed complete resolution either, although many of our cases have improved to the point where they are asymptomatic. Extra-genital disease seems to carry the best prognosis. 4 17 Complete resolution in adults is rare, and probably confined to extragenital lesions.4 In adult lichen sclerosus carcinoma may supervene,4 and although this complication has not been reported in childhood, Wallace recorded a case in whom carcinoma developed at the age of30 in a patient who had suffered persistent lichen sclerosus since childhood.4 sus et atrophicus in children misdiagnosed as sexual abuse. Br Med J 1987;294:1404-5.","journal-title":"Br Med J"},{"issue":"1","key":"ref_2","article-title":"Lichen sclerosus et atrophicus in children misdiagnosed as sexual abuse","volume":"21","author":"Priestley, B.L.; Bleehan, S.S.","year":"1987","unstructured":"Priestley BL, Bleehan SS. Lichen sclerosus et atrophicus in children misdiagnosed as sexual abuse. (Letter.) Br Med J 1987;295:21 1.","journal-title":"(Letter.) Br Med J"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1136\/bmj.295.6591.211-a","article-title":"Lichen sclerosus et atrophicus in children misdiagnosed as sexual abuse","volume":"295","author":"Davidson, D.C.; Clarke, M.D.B.; Kean, H.B.","year":"1987","unstructured":"Davidson DC, Clarke MDB, Kean HB. Lichen sclerosus et atrophicus in children misdiagnosed as sexual abuse. (Letter.) Br Med J 1987;295:211.","journal-title":"(Letter.) Br Med J"},{"key":"ref_4","first-page":"9","article-title":"Lichen sclerosus et atrophicus. Transactions of the St John's Hospital Dermatological","volume":"57","author":"Wallace, H.J.","year":"1971","unstructured":"Wallace HJ. Lichen sclerosus et atrophicus. Transactions of the St John's Hospital Dermatological Society 1971;57:9-30.","journal-title":"Society"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2133.1988.tb01748.x","article-title":"Lichen sclerosus et atrophicus and autoimmunity-a study of 350 women","volume":"118","author":"RH, Meyrick Thomas; CM, Ridley; DH, McGibbon; MM, Black","year":"1988","unstructured":"Meyrick Thomas RH, Ridley CM, McGibbon DH, Black MM. Lichen sclerosus et atrophicus and autoimmunity-a study of 350 women. Br J Dermatol 1988;118:41-6.","journal-title":"Br J Dermatol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1001\/archderm.1987.01660280087030","article-title":"Familial occurrence of lichen sclerosus et atrophicus","volume":"123","author":"Shirer, J.A.; Ray, M.C.","year":"1987","unstructured":"Shirer JA, Ray MC. Familial occurrence of lichen sclerosus et atrophicus. 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Cutis 1980;26:78-80.","journal-title":"Cutis"},{"key":"ref_9","first-page":"364","article-title":"A guide to dermatohistopathology","author":"Pinkus, H.; Mehregan, A.H.","year":"1976","unstructured":"Pinkus H, Mehregan AH. A guide to dermatohistopathology. 2nd ed. New York: Appleton-Century-Crofts, 1976:364-6.","edition":"2nd ed"},{"issue":"647-52","key":"ref_10","first-page":"5","article-title":"Lichen sclerosus et atrophicus in children","volume":"75","author":"Chernosky, M.E.; Derbes, V.J.; Burks, J.W.","year":"1957","unstructured":"Chernosky ME, Derbes VJ, Burks JW. Lichen sclerosus et atrophicus in children. Arch Dermatol 1957;75:647-52. '5 Ditkowski SP, Falk AB, Baker N, Schaffner M. Lichen sclerosus et atrophicus in childhood. Am J Dis Child 1956;9: 52-4.","journal-title":"Arch Dermatol; Lichen sclerosus et atrophicus in childhood"},{"key":"ref_11","first-page":"262","article-title":"Lichen sclerosus et atrophicus in children","volume":"17","author":"Torok, E.; Orley, J.; Goracz, G.; Dar6czy, J.","year":"1975","unstructured":"Torok E, Orley J, Goracz G, Dar6czy J. Lichen sclerosus et atrophicus in children. Modern Problems in Paediatrics 1975;17: 262-71.","journal-title":"Modern Problems in Paediatrics"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1365-2133.1953.tb13749.x","article-title":"Lichen sclerosus et atrophicus in young subjects","volume":"65","author":"Kindler, T.","year":"1953","unstructured":"Kindler T. Lichen sclerosus et atrophicus in young subjects. 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