{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:27:01Z","timestamp":1770816421216,"version":"3.50.1"},"reference-count":29,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Disease in Childhood"],"published-print":{"date-parts":[[1996,7,1]]},"DOI":"10.1136\/adc.75.1.67","type":"journal-article","created":{"date-parts":[[2008,12,22]],"date-time":"2008-12-22T23:07:28Z","timestamp":1229987248000},"page":"67-70","source":"Crossref","is-referenced-by-count":73,"title":["Neonatal cholestasis as the presenting feature in cystic fibrosis."],"prefix":"10.1136","volume":"75","author":[{"given":"P","family":"Lykavieris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Bernard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Hadchouel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"78","article-title":"Hepatic complication of cystic fibrosis","volume":"ii:","author":"Psacharopoulos, H.T.; Howard, E.R.; Portman, B.; Mowat, A.P.; Williams, R.","year":"1981","unstructured":"Psacharopoulos HT, Howard ER, Portman B, Mowat AP, Williams R. Hepatic complication of cystic fibrosis. Lancet 1981; ii: 78-80.","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1055\/s-2008-1040717","article-title":"Cystic fibrosis: its influence on the liver biliary tree, and bile salt metabolism","volume":"2","author":"Isenberg, J.N.","year":"1982","unstructured":"Isenberg JN. Cystic fibrosis: its influence on the liver biliary tree, and bile salt metabolism. Semin Liver Dis 1982; 2: 302-13.","journal-title":"Semin Liver Dis"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0037-198X(87)90040-X","article-title":"Cystic fibrosis: overview","volume":"12","author":"Fernald, G.W.; Boat, T.F.","year":"1987","unstructured":"Fernald GW, Boat TF. Cystic fibrosis: overview. Semin Roentgenol 1987; 12: 87-96.","journal-title":"Semin Roentgenol"},{"key":"ref_4","first-page":"182","article-title":"Jaundice in mucoviscidosis (fibrocystic disease of pancreas)","volume":"89","author":"Gatzimos, C.D.; Jowitt, R.H.","year":"1955","unstructured":"Gatzimos CD, Jowitt RH. Jaundice in mucoviscidosis (fibrocystic disease of pancreas). Am J Dis Child 1955; 89: 182-6.","journal-title":"Am J Dis Child"},{"issue":"99","key":"ref_5","first-page":"804","article-title":"The occurrence of intestinal atresia in newborn with meconium ileus","volume":"1960","author":"Bernstein, J.; Vawter, G.; Harris, G.B.C.; Young, V.; Hillman, S.L.","unstructured":"Bernstein J, Vawter G, Harris GBC, Young V, Hillman SL. The occurrence of intestinal atresia in newborn with meconium ileus.AmJDis Child 1960; 99: 804-18.","journal-title":"AmJDis Child"},{"key":"ref_6","first-page":"645","article-title":"The pathology of liver cirrhosis in patients with cystic fibrosis of the pancreas","volume":"89","author":"Shier, K.J.; Horm, R.C.","year":"1963","unstructured":"Shier KJ, Horm RC. The pathology of liver cirrhosis in patients with cystic fibrosis of the pancreas. Can Med Assoc J 1963; 89: 645-51.","journal-title":"Can Med Assoc J"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1001\/archpedi.1965.02090020103003","article-title":"Meconium ileus","volume":"109","author":"Holsclaw, D.S.; Eckstein, H.B.; Nixon, H.H.","year":"1965","unstructured":"Holsclaw DS, Eckstein HB, Nixon HH. Meconium ileus. Am JDis Child 1965; 109: 101-13.","journal-title":"Am JDis Child"},{"key":"ref_8","first-page":"74","article-title":"Prolonged obstructive jaundice","volume":"115","author":"Talamo, R.C.; Hendren, W.H.","year":"1968","unstructured":"Talamo RC, Hendren WH. Prolonged obstructive jaundice. AmJDis Child 1968; 115: 74-9.","journal-title":"AmJDis Child"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1136\/adc.46.250.805","article-title":"Prolonged neonatal jaundice in cystic fibrosis","volume":"46","author":"Valman, H.B.; France, N.E.; Wallis, P.G.","year":"1971","unstructured":"Valman HB, France NE, Wallis PG. Prolonged neonatal jaundice in cystic fibrosis. Arch Dis Child 1971; 46: 805-9.","journal-title":"Arch Dis Child"},{"key":"ref_10","first-page":"161","article-title":"Neonatal jaundice associated with cystic fibrosis","volume":"123","author":"Taylor, W.F.; Qaqundah, B.Y.; Calif, I.","year":"1972","unstructured":"Taylor WF, Qaqundah BY, Calif I. Neonatal jaundice associated with cystic fibrosis. Am J Dis Child 1972; 123: 161-2.","journal-title":"Am J Dis Child"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/S0022-3476(77)80921-9","article-title":"Prolonged obstructive jaundice and giant cell hepatitis in an infant with cystic fibrosis","volume":"91","author":"Rosenstein, B.J.; Oppenheimer, E.H.","year":"1977","unstructured":"Rosenstein BJ, Oppenheimer EH. Prolonged obstructive jaundice and giant cell hepatitis in an infant with cystic fibrosis. _J Pediatr 1977; 91: 1022-5.","journal-title":"_J Pediatr"},{"key":"ref_12","first-page":"351","article-title":"Lsiver involvement in cystic fibrosis","volume":"33","author":"Schwarz, H.P.; Kraemer, R.; Thurnheer, U.; Rossi, E.","year":"1978","unstructured":"Schwarz HP, Kraemer R, Thurnheer U, Rossi E. Lsiver involvement in cystic fibrosis. Helv Paediat Acta 1978; 33: 351-64.","journal-title":"Helv Paediat Acta"},{"key":"ref_13","first-page":"1060","article-title":"Intrahepatic compression of the common bile duct in cystic fibrosis","volume":"93","author":"Vitulio, B.B.; Rochon, L.; Seemayer, A.T.; Beardmore, H.; De Belle, C.R.","year":"1978","unstructured":"Vitulio BB, Rochon L, Seemayer AT, Beardmore H, De Belle CR. Intrahepatic compression of the common bile duct in cystic fibrosis.JPediarr 1978; 93: 1060-1.","journal-title":"JPediarr"},{"key":"ref_14","first-page":"268","article-title":"Cystic fibrosis manifested as focal biliary cirrhosis in a newborn infant with congenital heart disease","volume":"135","author":"Cooper, H.S.; Oppenheimer, E.H.","year":"1979","unstructured":"Cooper HS, Oppenheimer EH. Cystic fibrosis manifested as focal biliary cirrhosis in a newborn infant with congenital heart disease. Johns Hopkins MedJf 1979; 135: 268-73.","journal-title":"Johns Hopkins MedJf"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1177\/000992288502400211","article-title":"Cystic fibrosis mistaken for idiopathic biliary atresia","volume":"24","author":"Perkins, W.G.; Klein, G.L.; Beckerman, R.C.","year":"1985","unstructured":"Perkins WG, Klein GL, Beckerman RC. Cystic fibrosis mistaken for idiopathic biliary atresia. Clin Pediatr (Phila) 1985; 24: 107-9.","journal-title":"Clin Pediatr (Phila)"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/hep.1840060514","article-title":"Nonsyndromatic paucity of interlobular bile ducts: light and electron microscopic evaluation of sequential liver biopsies in early childhood","volume":"6","author":"Kahn, E.; Daum, F.; Markowitz, J.","year":"1986","unstructured":"Kahn E, Daum F, Markowitz J, et al. Nonsyndromatic paucity of interlobular bile ducts: light and electron microscopic evaluation of sequential liver biopsies in early childhood. Hepatology 1986; 6: 890-901.","journal-title":"Hepatology"},{"key":"ref_17","first-page":"106","article-title":"Neonatal jaundice in cystic fibrosis: a conservative approach is not always justified","volume":"43","author":"Festen, C.; Kuyper, F.; Holland, R.; van Haelst, U.","year":"1988","unstructured":"Festen C, Kuyper F, Holland R, van Haelst U. Neonatal jaundice in cystic fibrosis: a conservative approach is not always justified. Z Kinderchir 1988; 43: 106-7.","journal-title":"Z Kinderchir"},{"key":"ref_18","first-page":"127","article-title":"Neonatal hepatitis syndrome with paucity of interlobular bile ducts in cystic fibrosis","volume":"1","author":"Furuya, K.N.; Roberts, E.A.; Canny, G.J.; James Phillips, M.","year":"1991","unstructured":"Furuya KN, Roberts EA, Canny GJ, James Phillips M. Neonatal hepatitis syndrome with paucity of interlobular bile ducts in cystic fibrosis. J Pediatr Gastoenterol Nutr 1991; 1: 127-30.","journal-title":"J Pediatr Gastoenterol Nutr"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/00005176-199101000-00024","article-title":"Biliary infusion therapy in the inspissated bile syndrome of cystic fibrosis","volume":"12","author":"Evans, J.S.; George, D.E.; Mollit, D.","year":"1991","unstructured":"Evans JS, George DE, Mollit D. Biliary infusion therapy in the inspissated bile syndrome of cystic fibrosis. J Pediatr Gastoenterol Nutr 1991; 12: 131-5.","journal-title":"J Pediatr Gastoenterol Nutr"},{"key":"ref_20","first-page":"371","article-title":"Un cas inusite de musoviscidose: atteinte hepatique neonatale","volume":"38","author":"Banchand, J.P.","year":"1967","unstructured":"Banchand JP. Un cas inusite de musoviscidose: atteinte hepatique neonatale. Laval Medical 1967; 38: 371-2.","journal-title":"Laval Medical"},{"key":"ref_21","first-page":"27","article-title":"Deux observations inhabituelles de mucoviscidose, detresse respiratoire neonatale et forme hepatique precoce","author":"Fontan, A.; Verger, P.; Battin, J.J.; Kermarec, J.; Houssiaux, J.P.","year":"1984","unstructured":"Fontan A, Verger P, Battin JJ, Kermarec J, Houssiaux JP. Deux observations inhabituelles de mucoviscidose, detresse respiratoire neonatale et forme hepatique precoce. Ann Pediatr 1984; 27-28: 340-7."},{"issue":"5","key":"ref_22","first-page":"115","article-title":"Malformation des voies biliaires intrahepatiques dans la maladie fibro-kystique du pancreas","volume":"1960","author":"Giegler, I.","unstructured":"Giegler I. Malformation des voies biliaires intrahepatiques dans la maladie fibro-kystique du pancreas. Ann Anat Pathol 1960; 5: 115-26.","journal-title":"Ann Anat Pathol"},{"key":"ref_23","first-page":"145","article-title":"Ictere retentionnel neonatal revelateur de la mucoviscidose","volume":"19","author":"Raynaud, E.J.; Hennequet, A.; Menut, G.; Lavignon, A.; Malpuech, G.; Lagarde, R.","year":"1972","unstructured":"Raynaud EJ, Hennequet A, Menut G, Lavignon A, Malpuech G, Lagarde R. Ictere retentionnel neonatal revelateur de la mucoviscidose. Ann Pidiatr 1972; 19: 145-51."},{"key":"ref_24","first-page":"828","article-title":"Mucoviscidose et cirrhose biliaire","volume":"25","author":"Grislain, JR, Mainard; R, De Berranger; P, Brelet; G, De Ferron; C.","year":"1968","unstructured":"Grislain JR, Mainard R, De Berranger P, Brelet G, De Ferron C. Mucoviscidose et cirrhose biliaire. Arch Fr Pidiatr 1968; 25: 828.","journal-title":"Arch Fr Pidiatr"},{"key":"ref_25","first-page":"636","article-title":"Prolonged obstructive jaundice including calculous and noncalculous gallbladder conditions. Pediatric clinical gastroenterology","author":"Roy, C.C.; Silverman, A.; Alagille, D.","year":"1995","unstructured":"Roy CC, Silverman A, Alagille D. Prolonged obstructive jaundice including calculous and noncalculous gallbladder conditions. Pediatric clinical gastroenterology. 4th Ed. St Louis: Mosby, 1995: 636-83.","edition":"4th Ed"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0022-3476(75)80351-9","article-title":"Hepatic changes in young infants with cystic fibrosis. Possible relation to focal biliary cirrhosis","volume":"86","author":"Oppenheimer, E.H.; Esterly, JR","year":"1975","unstructured":"Oppenheimer EH, Esterly JR. Hepatic changes in young infants with cystic fibrosis. Possible relation to focal biliary cirrhosis. J Pediatr 1975; 86: 683-9.","journal-title":"J Pediatr"},{"key":"ref_27","first-page":"159","article-title":"Cystic fibrosis of the pancreas","volume":"96","author":"Oppenheimer, E.H.; Esterly, JR","year":"1973","unstructured":"Oppenheimer EH, Esterly JR. Cystic fibrosis of the pancreas. Arch Pathol 1973; 96: 159-4.","journal-title":"Arch Pathol"},{"issue":"314","key":"ref_28","article-title":"First reported use of ursodeoxycholic acid in the treatment ofprolonged neonatal jaundice in a cystic fibrosis infant","volume":"8","author":"Watson, J.B.G.; Babu, M.S.V.; Shortt, C.; O'Halloran, E.T.","year":"1992","unstructured":"Watson JBG, Babu MSV, Shortt C, O'Halloran ET. First reported use of ursodeoxycholic acid in the treatment ofprolonged neonatal jaundice in a cystic fibrosis infant. Pediatr Pulmonol 1992; suppl 8: 314.","journal-title":"Pediatr Pulmonol"},{"key":"ref_29","first-page":"393","article-title":"Analysis of risk factors for the development of liver disease associated with cystic fibrosis","volume-title":"I Pediatr","volume":"124","author":"Colombo, C.; Apostolo, M.G.; Ferrari, M.","year":"1994","unstructured":"Colombo C, Apostolo MG, Ferrari M, et al. Analysis of risk factors for the development of liver disease associated with cystic fibrosis. I Pediatr 1994; 124: 393-9."}],"container-title":["Archives of Disease in Childhood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/adc.75.1.67","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T21:49:25Z","timestamp":1601070565000},"score":1,"resource":{"primary":{"URL":"https:\/\/adc.bmj.com\/lookup\/doi\/10.1136\/adc.75.1.67"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/adc.75.1.67","relation":{},"ISSN":["0003-9888","1468-2044"],"issn-type":[{"value":"0003-9888","type":"print"},{"value":"1468-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7,1]]}}}