{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:27:49Z","timestamp":1777379269071,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","issue":"1-2","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acupunct Med"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate the evidence for the efficacy of acupuncture in the treatment of anxiety and anxiety disorders by systematic review of the relevant research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Searches of the major biomedical databases (MEDLINE, EMBASE, ClNAHL, PsycINFO, Cochrane Library) were conducted between February and July 2004. Specialist complementary medicine databases were also searched and efforts made to identify unpublished research. No language restrictions were imposed and translations were obtained where necessary. Study methodology was appraised and clinical commentaries obtained for studies reporting clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twelve controlled trials were located, of which 10 were randomised controlled trials (RCTs). Four RCTs focused on acupuncture in generalised anxiety disorder or anxiety neurosis, while six focused on anxiety in the perioperative period. No studies were located on the use of acupuncture specifically for panic disorder, phobias or obsessive-compulsive disorder. In generalised anxiety disorder or anxiety neurosis, it is difficult to interpret the findings of the studies of acupuncture because of the range of interventions against which acupuncture was compared. All trials reported positive findings but the reports lacked many basic methodological details. Reporting of the studies of perioperative anxiety was generally better and the initial indications are that acupuncture, specifically auricular acupuncture, is more effective than acupuncture at sham points and may be as effective as drug therapy in this situation. The results were, however, based on subjective measures and blinding could not be guaranteed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Positive findings are reported for acupuncture in the treatment of generalised anxiety disorder or anxiety neurosis but there is currently insufficient research evidence for firm conclusions to be drawn. No trials of acupuncture for other anxiety disorders were located. There is some limited evidence in favour of auricular acupuncture in perioperative anxiety. Overall, the promising findings indicate that further research is warranted in the form of well designed, adequately powered studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/aim.25.1-2.1","type":"journal-article","created":{"date-parts":[[2009,4,8]],"date-time":"2009-04-08T12:53:12Z","timestamp":1239195192000},"page":"1-10","source":"Crossref","is-referenced-by-count":161,"title":["Acupuncture for Anxiety and Anxiety Disorders \u2013 a Systematic Literature Review"],"prefix":"10.1177","volume":"25","author":[{"given":"Karen","family":"Pilkington","sequence":"first","affiliation":[{"name":"School of Integrated, Health University of Westminster, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham","family":"Kirkwood","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Public Health and Primary Care Medicine, Imperial College, London, UK[previously] Research Council for Complementary Medicine, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hagen","family":"Rampes","sequence":"additional","affiliation":[{"name":"Barnet, Enfield & Haringey Mental Health, NHS Trust, Northwest Community, Mental Health Team, Edgware, Middlesex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike","family":"Cummings","sequence":"additional","affiliation":[{"name":"British Medical, Acupuncture Society, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Richardson","sequence":"additional","affiliation":[{"name":"Faculty of Health and Social Work, University of Plymouth, Plymouth, Devon, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,6,1]]},"reference":[{"key":"bibr1-aim.25.1-2.1","unstructured":"ChurchillR, BarbuiC, FurukawaT, GilbodyS, HatcherS, HazellP  Depression, Anxiety and Neurosis Group. About The Cochrane Collaboration (Cochrane Review Groups (CRGs)) 2003; Issue 1. Art. No: DEPRESSN."},{"key":"bibr2-aim.25.1-2.1","unstructured":"JenkinsR. Introduction to generalised anxiety. WHO UK Collaborating Centre 2005. National Library for Health. Mental Health Specialist Library. http:\/\/www.library.nhs.uk\/mentalhealth\/ViewResource.aspx?resID=79787&tabID=288 (accessed 8 May 2006)."},{"key":"bibr3-aim.25.1-2.1","unstructured":"World Health Organisation. The world health report 2004 -changing history. http:\/\/www.who.int\/whr\/2004\/en\/index.html (accessed 8 May 2006)."},{"key":"bibr4-aim.25.1-2.1","volume-title":"Summary Report.","author":"Office for National Statistics","year":"2000"},{"key":"bibr5-aim.25.1-2.1","unstructured":"National Institute for Health and Clinical Excellence. Anxiety: management of anxiety (panic disorder, with or without agoraphobia, and generalised anxiety disorder) in adults in primary, secondary and community care. Clinical Guideline 22 (CG022). National Institute for Health and Clinical Excellence 2004. http:\/\/www.nice.org.uk\/page.aspx?o=cg022niceguideline (accessed 8 May 2006)."},{"key":"bibr6-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2004.10.627"},{"key":"bibr7-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.18.1569"},{"key":"bibr8-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-440X(98)90027-X"},{"key":"bibr9-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.11.1851"},{"key":"bibr10-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.2.289"},{"key":"bibr11-aim.25.1-2.1","first-page":"67","volume-title":"Review of Psychiatry","volume":"19","author":"Rainone F.","year":"2000"},{"key":"bibr12-aim.25.1-2.1","unstructured":"ARRC (Acupuncture Research Resource Centre). Depression, Anxiety and Acupuncture. Briefing paper no 9 2002."},{"issue":"7","key":"bibr13-aim.25.1-2.1","first-page":"29","volume":"181","author":"Jorm AF","year":"2004","journal-title":"Med J Aust"},{"key":"bibr14-aim.25.1-2.1","volume-title":"Undertaking Systematic Reviews of Research on Effectiveness.","author":"NHS Centre for Reviews and Dissemination","year":"2001"},{"key":"bibr15-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-11624"},{"issue":"2","key":"bibr16-aim.25.1-2.1","first-page":"117","volume":"26","author":"Liu GZ","year":"1998","journal-title":"Am J Acupunct"},{"issue":"4","key":"bibr17-aim.25.1-2.1","first-page":"17","volume":"17","author":"Liu G","year":"1998","journal-title":"Shanghai J Acupuncture Moxibustion"},{"issue":"26","key":"bibr18-aim.25.1-2.1","volume":"3","author":"Chao-Ying W","year":"2003","journal-title":"Hunan Journal of Chinese Medicine"},{"issue":"1","key":"bibr19-aim.25.1-2.1","first-page":"55","volume":"23","author":"Zhang H","year":"2003","journal-title":"J Tradit Chin Med"},{"key":"bibr20-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.3727\/036012986816359229"},{"issue":"6","key":"bibr21-aim.25.1-2.1","first-page":"9","volume":"22","author":"Zhou ZH","year":"2003","journal-title":"Shanghai Journal of Acupuncture and Moxibustion"},{"key":"bibr22-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200306000-00005"},{"issue":"3","key":"bibr23-aim.25.1-2.1","first-page":"205","volume":"15","author":"Lewis GB","year":"1987","journal-title":"method. Am J Acupunct"},{"issue":"3","key":"bibr24-aim.25.1-2.1","first-page":"97","volume":"154","author":"Uskok M","year":"1995","journal-title":"Gazz Med Ital"},{"key":"bibr25-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-200102000-00049"},{"key":"bibr26-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200111000-00024"},{"key":"bibr27-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200406000-00011"},{"issue":"2","key":"bibr28-aim.25.1-2.1","first-page":"254","volume":"22","author":"Apchel VY","year":"1996","journal-title":"Hum Physiol"},{"issue":"1","key":"bibr29-aim.25.1-2.1","first-page":"56","volume":"26","author":"De Nicola A","year":"1979","journal-title":"Annali di Neuropsichiatria Psicoanalisi"},{"issue":"4","key":"bibr30-aim.25.1-2.1","first-page":"327","volume":"21","author":"Dong Jiang T.","year":"1993","journal-title":"Am J Acupunct"},{"issue":"2","key":"bibr31-aim.25.1-2.1","first-page":"263","volume":"29","author":"Grenet Cordoves ES","year":"1988","journal-title":"Revista del Hospital Psiquiatrico de la Habana"},{"issue":"2","key":"bibr32-aim.25.1-2.1","first-page":"124","volume":"24","author":"Guo N","year":"2004","journal-title":"J Tradit Chin Med"},{"issue":"3","key":"bibr33-aim.25.1-2.1","first-page":"165","volume":"24","author":"Hai RH","year":"2004","journal-title":"Chinese Acupuncture & Moxibustion"},{"issue":"2","key":"bibr34-aim.25.1-2.1","first-page":"102","volume":"88","author":"Kochetkov VD","year":"1988","journal-title":"Zh Nevropatol Psikhiatr Im S S Korsakova"},{"key":"bibr35-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X79000210"},{"issue":"11","key":"bibr36-aim.25.1-2.1","first-page":"1708","volume":"86","author":"Markelova VF","year":"1986","journal-title":"Zh Nevropatol Psikhiatr Im S S Korsakova"},{"key":"bibr37-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.16.1.19"},{"issue":"29","key":"bibr38-aim.25.1-2.1","first-page":"1918","volume":"67","author":"Roccia L","year":"1976","journal-title":"Minerva Med"},{"issue":"8","key":"bibr39-aim.25.1-2.1","first-page":"645","volume":"93","author":"Yamashita T","year":"1991","journal-title":"Japanese. Seishin Shinkeigaku Zasshi"},{"key":"bibr40-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(95)00134-4"},{"key":"bibr41-aim.25.1-2.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38987.492014.94"}],"container-title":["Acupuncture in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1136\/aim.25.1-2.1","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1136\/aim.25.1-2.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:13:42Z","timestamp":1777367622000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1136\/aim.25.1-2.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":41,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1136\/aim.25.1-2.1"],"URL":"https:\/\/doi.org\/10.1136\/aim.25.1-2.1","relation":{},"ISSN":["0964-5284","1759-9873"],"issn-type":[{"value":"0964-5284","type":"print"},{"value":"1759-9873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}