{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T09:18:14Z","timestamp":1793351894209,"version":"4.5.0"},"reference-count":33,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Arch Dis Child"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>In cystic fibrosis (CF), problems with sleep, eating\/mealtime behaviours, physiotherapy adherence and parental mental health issues are common, yet their natural history and the extent of service use to address them are unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Follow up the 2007 cohort to determine: (1) prevalence of child sleep, eating\/mealtime behaviours, physiotherapy adherence, and externalising\/internalising problem behaviours and primary caregiver mental health status after a 3-year period; (2) natural history of child behaviours; (3) potentially modifiable predictors of persistent problems; and (4) service use for behaviours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective cohort. Setting: Royal Children's Hospital, Monash Medical Centre and Sydney Children's Hospital (Australia) CF clinics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Caregivers, of children aged 3\u20138 years, who completed the baseline questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Child sleep, eating\/mealtime behaviours, adherence with therapy and externalising and internalising behaviours. Predictors: parenting style (low warmth), caregiver mental health status and sleep quality at baseline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>102 of 116 (88%) families participated. The prevalence of sleep and eating\/mealtime problems at follow-up was similar to baseline. The prevalence of caregiver mental health symptoms remained higher than the community data. 71 out of 102 (70%) of the children experienced at least one persistent behaviour problem. Caregiver mental health difficulties predicted persistent child moderate to severe sleep problems (adjusted OR 6.5, 95% CI 1.2 to 36.2, p=0.03) and their persistently poor adherence to the physiotherapy regimen (adjusted OR 3.5, 95% CI 1.3 to 9.2, p=0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Child problem behaviours are common in children with CF, persist and are often predicted by the mental health of the parent. Routine surveillance for and management of child problem behaviours are recommended.<\/jats:p><\/jats:sec>","DOI":"10.1136\/archdischild-2011-301527","type":"journal-article","created":{"date-parts":[[2012,5,20]],"date-time":"2012-05-20T12:31:07Z","timestamp":1337517067000},"page":"625-631","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["The natural history and predictors of persistent problem behaviours in cystic fibrosis: a multicentre, prospective study"],"prefix":"10.1136","volume":"97","author":[{"given":"Jane","family":"Sheehan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Massie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Hay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Jaffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Glazner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harriet","family":"Hiscock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2012,5,18]]},"reference":[{"key":"2023011221401444000_97.7.625.1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.5694\/j.1326-5377.2000.tb124123.x","article-title":"Newborn screening for cystic fibrosis in Victoria: 10 years' experience (1989-1998).","volume":"172","author":"Massie","year":"2000","journal-title":"Med J Aust"},{"key":"2023011221401444000_97.7.625.2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00099506"},{"key":"2023011221401444000_97.7.625.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60327-5"},{"key":"2023011221401444000_97.7.625.4","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0002-7138(09)60415-5","article-title":"Psychiatric disorder in children with physical disabilities.","volume":"24","author":"Breslau","year":"1985","journal-title":"J Am Acad Child Psychiatry"},{"key":"2023011221401444000_97.7.625.5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2214.2003.00324.x"},{"key":"2023011221401444000_97.7.625.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2010.07.002"},{"key":"2023011221401444000_97.7.625.7","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21322"},{"key":"2023011221401444000_97.7.625.8","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/22.6.881"},{"key":"2023011221401444000_97.7.625.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(00)70101-6"},{"key":"2023011221401444000_97.7.625.10","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcp.0000183051.18611.e4"},{"key":"2023011221401444000_97.7.625.11","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.24.3.274"},{"key":"2023011221401444000_97.7.625.12","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsj096"},{"key":"2023011221401444000_97.7.625.13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.1991.tb02540.x"},{"key":"2023011221401444000_97.7.625.14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2214.1998.00057.x"},{"key":"2023011221401444000_97.7.625.15","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.150789"},{"key":"2023011221401444000_97.7.625.16","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2569"},{"key":"2023011221401444000_97.7.625.17","unstructured":"Wake M Hiscock H Bayer J . 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