{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:47:38Z","timestamp":1788306458681,"version":"build-2803163510"},"reference-count":24,"publisher":"BMJ","issue":"2","funder":[{"DOI":"10.13039\/501100002181","name":"Lullaby Trust","doi-asserted-by":"publisher","award":["259"],"award-info":[{"award-number":["259"]}],"id":[{"id":"10.13039\/501100002181","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"accepted":{"date-parts":[[2016,6,27]]},"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                  <jats:title>Background and objective<\/jats:title>\n                  <jats:p>The American Academy of Pediatrics recommends that preterm infants complete a predischarge \u2018car seat challenge\u2019 observation for cardiorespiratory compromise while in a car seat. This static challenge does not consider the more upright position in a car or the vibration of the seat when the car is moving. This pilot study was designed to assess the cardiorespiratory effects of vibration, mimicking the effect of being in a moving car, on preterm and term infants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A simulator was designed to reproduce vertical vibration similar to that in a rear-facing car seat at 30\u2005mph. 19 healthy newborn term and 21 preterm infants, ready for hospital discharge, underwent cardiorespiratory measurements while lying flat in a cot (baseline), static in the seat (30\u00b0), simulator (40\u00b0) and during motion (vibration 40\u00b0).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Median test age was 13\u2005days (range 1\u201365\u2005days) and median weight was 2.5\u2005kg (IQR: 2.1\u20133.1\u2005kg).<\/jats:p>\n                  <jats:p>Compared with baseline observations, only the total number of desaturations was significantly increased when infants were placed at 30\u00b0 (p=0.03). At 40\u00b0, or with vibration, respiratory and heart rates increased and oxygen saturation decreased significantly. Profound desaturations &lt;85% significantly increased during motion, regardless of gestational age.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This is the first study to assess the effect of motion on infants seated in a car safety seat. Term and preterm infants showed significant signs of potentially adverse cardiorespiratory effects in the upright position at 40\u00b0, particularly with simulated motion, not identified in the standard challenge. A larger study is required to investigate the significance of these results.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/archdischild-2016-310730","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T23:09:20Z","timestamp":1475276960000},"page":"F136-F141","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Is the infant car seat challenge useful? 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