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In general, intermittent wheezing should be treated with intermittent bronchodilator therapy, and a controller therapy should be prescribed for a young child with recurrent wheezing only if positively indicated, and only then if carefully monitored for efficacy. Good multidisciplinary support, attention to environmental exposition and education are essential in managing this common condition. This article analyses the pathophysiological basis of wheezing in infancy and critically discusses the evolution of the scientific progress over time in this unique field of respiratory medicine.<\/jats:p>","DOI":"10.1136\/archdischild-2016-311639","type":"journal-article","created":{"date-parts":[[2016,10,6]],"date-time":"2016-10-06T00:39:31Z","timestamp":1475714371000},"page":"371-375","update-policy":"http:\/\/dx.doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Infantile wheeze: rethinking dogma"],"prefix":"10.1136","volume":"102","author":[{"given":"Fernando Maria","family":"de Benedictis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Bush","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,10,4]]},"reference":[{"key":"key-10.1136\/archdischild-2016-311639-1","doi-asserted-by":"crossref","first-page":"g15","DOI":"10.1136\/bmj.g15","article-title":"Managing wheeze in preschool children","volume":"348","author":"Bush","year":"2014","journal-title":"BMJ"},{"key":"key-10.1136\/archdischild-2016-311639-2","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1016\/S0140-6736(14)60615-2","article-title":"Diagnosis, management, and prognosis of preschool wheeze","volume":"383","author":"Ducharme","year":"2014","journal-title":"Lancet"},{"key":"key-10.1136\/archdischild-2016-311639-3","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1183\/09031936.00199913","article-title":"Classification and pharmacological treatment of preschool wheezing: changes since 2008","volume":"43","author":"Brand","year":"2014","journal-title":"Eur Respir J"},{"key":"key-10.1136\/archdischild-2016-311639-4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0091-6749(81)90077-4","article-title":"Postgraduate course presentation. 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