{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:33:08Z","timestamp":1793493188415,"version":"4.5.0"},"reference-count":7,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"accepted":{"date-parts":[[2017,8,30]]},"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>Although major cooling trials (and subsequent guidelines) excluded babies with mild encephalopathy, anecdotal evidence suggests that cooling is often offered to these infants. We report a national survey on current cooling practices for babies with mild encephalopathy in the UK. From 74 neonatal units contacted, 68 were cooling centres. We received 54 responses (79%) and included 48 (five excluded due to incomplete data and one found later not to offer cooling). Of these, 36 centres (75%) offered cooling to infants with mild encephalopathy. Although most of the participating units reported targeting 33\u201334\u00b0C core temperature, seven (19%) considered initiating cooling beyond 6\u2009hours of age and 13 (36%) discontinued cooling prior to 72\u2009hours. Babies were ventilated for cooling in two (6%) units and 13 (36%) sedated all cooled babies. Enteral feeding was withheld in 15 (42%) units and reduced below 25% of requirements in eight (22%) units. MRI and neurodevelopmental outcome evaluation were offered to all cooled babies in 29 (80%) and 27 (75%) units, respectively. Further research is necessary to ensure optimal neuroprotection in mild encephalopathy.<\/jats:p>","DOI":"10.1136\/archdischild-2017-313320","type":"journal-article","created":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T20:11:09Z","timestamp":1506197469000},"page":"F388-F390","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":77,"title":["Therapeutic hypothermia in mild neonatal encephalopathy: a national survey of practice in the UK"],"prefix":"10.1136","volume":"103","author":[{"given":"V\u00e2nia","family":"Oliveira","sequence":"first","affiliation":[{"name":"Centre for Perinatal Neuroscience, Department of Paediatrics, Imperial College London, London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dev Prya","family":"Singhvi","sequence":"additional","affiliation":[{"name":"Centre for Perinatal Neuroscience, Department of Paediatrics, Imperial College London, London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Montaldo","sequence":"additional","affiliation":[{"name":"Centre for Perinatal Neuroscience, Department of Paediatrics, Imperial College London, London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0075-0103","authenticated-orcid":false,"given":"Peter J","family":"Lally","sequence":"additional","affiliation":[{"name":"Centre for Perinatal Neuroscience, Department of Paediatrics, Imperial College London, London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephine","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Centre for Perinatal Neuroscience, Department of Paediatrics, Imperial College London, London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Manerkar","sequence":"additional","affiliation":[{"name":"Neonatal Unit, Lokmanya Tilak Municipal General Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seetha","family":"Shankaran","sequence":"additional","affiliation":[{"name":"Department of Neonatal-Perinatal Medicine, Wayne State University, Detroit, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhin","family":"Thayyil","sequence":"additional","affiliation":[{"name":"Centre for Perinatal Neuroscience, Department of Paediatrics, Imperial College London, London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,9,23]]},"reference":[{"key":"2025090510265670000_103.4.F388.1","unstructured":"National Institute for Health and Care Excellence. Therapeutic hypothermia with intracorporeal temperature monitoring for hypoxic perinatal brain injury.\u00a0Interventional procedures guidance [IPG347]. 2010 http:\/\/nice.org.uk\/guidance\/ipg347 (accessed on 22\/08\/2017)."},{"key":"2025090510265670000_103.4.F388.2","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/jpc.13378","article-title":"Eligibility criteria for therapeutic hypothermia: From trials to clinical practice","volume":"53","author":"Mehta","year":"2017","journal-title":"J Paediatr Child Health"},{"key":"2025090510265670000_103.4.F388.3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003311.pub3"},{"key":"2025090510265670000_103.4.F388.4","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.neuroscience.2015.12.046","article-title":"White matter apoptosis is increased by delayed hypothermia and rewarming in a neonatal piglet model of hypoxic ischemic encephalopathy","volume":"316","author":"Wang","year":"2016","journal-title":"Neuroscience"},{"key":"2025090510265670000_103.4.F388.5","first-page":"17707671","article-title":"How long is sufficient for optimal neuroprotection with cerebral cooling after ischemia in fetal sheep?","volume":"271678X","author":"Davidson","year":"2017","journal-title":"J Cereb Blood Flow Metab"},{"key":"2025090510265670000_103.4.F388.6","doi-asserted-by":"crossref","unstructured":"Lally PJ , Montaldo P , Oliveira V , et al . Residual brain injury after early discontinuation of cooling therapy in mild neonatal encephalopathy. Arch Dis Child Fetal Neonatal Ed. In Press 2017.","DOI":"10.1136\/archdischild-2017-313321"},{"key":"2025090510265670000_103.4.F388.7","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1976.00500100030012"}],"container-title":["Archives of Disease in Childhood - Fetal and Neonatal Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/archdischild-2017-313320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T17:46:13Z","timestamp":1757094373000},"score":1,"resource":{"primary":{"URL":"https:\/\/fn.bmj.com\/lookup\/doi\/10.1136\/archdischild-2017-313320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,23]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,6,19]]},"published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1136\/archdischild-2017-313320"],"URL":"https:\/\/doi.org\/10.1136\/archdischild-2017-313320","relation":{},"ISSN":["1359-2998","1468-2052"],"issn-type":[{"value":"1359-2998","type":"print"},{"value":"1468-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,23]]}}}