{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:45:00Z","timestamp":1788669900723,"version":"build-2803163510"},"reference-count":6,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Arch Dis Child"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the burden of clinically significant neonatal jaundice (SNJ) in Taiwan, 2000<jats:bold>\u2013<\/jats:bold>2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>The nationwide, population-based health insurance database in Taiwan was used to investigate the incidence, kernicterus rate and mortality rates of SNJ cohort born between 2000 and 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2000 to 2010, up to 242\u2009546 patients admitted with neonatal jaundice (NJ) were identified. The incidence of SNJ was 5.9% in 2000 and increased to 13.7% in 2010 (P&lt;0.001). The mortality rate significantly decreased from 0.51% in 2000 to 0.26% in 2010 (P&lt;0.001) and the average incidence of kernicterus was 0.86 per 100\u2009000 live births, indicating dramatically decreased rates compared with earlier rates in Taiwan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In spite of the increased incidence rates, the rates of mortality and kernicterus in patients with NJ significantly declined in Taiwan. The public health prevention programme, clinicians\u2019 awareness and effective management might contribute to the reduction of these acute severe sequelae.<\/jats:p><\/jats:sec>","DOI":"10.1136\/archdischild-2017-314063","type":"journal-article","created":{"date-parts":[[2018,2,22]],"date-time":"2018-02-22T17:41:08Z","timestamp":1519321268000},"page":"927-929","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Outcomes of neonatal jaundice in Taiwan"],"prefix":"10.1136","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1613-6538","authenticated-orcid":false,"given":"Pei-Chen","family":"Tsao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Ling","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Chen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Huang","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Shih","family":"Shiau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szu-Hui","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jue","family":"Soong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Jy","family":"Jeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang-Jen","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,2,22]]},"reference":[{"key":"2020050712425432000_103.10.927.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.297"},{"key":"2020050712425432000_103.10.927.2","doi-asserted-by":"publisher","DOI":"10.1159\/000330055"},{"key":"2020050712425432000_103.10.927.3","first-page":"1","article-title":"Neonatal Hyperbilirubinemia and Erythrocyte G-6-PD Deficiency in Chinese Newborn Infants","volume":"18","author":"Chang","year":"1977","journal-title":"Acta Paediatr Sin"},{"key":"2020050712425432000_103.10.927.4","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.197616"},{"key":"2020050712425432000_103.10.927.5","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000445708","article-title":"Neonatal Jaundice in Low- and Middle-Income Countries: Lessons and Future Directions from the 2015 Don Ostrow Trieste Yellow Retreat","volume":"110","author":"Greco","year":"2016","journal-title":"Neonatology"},{"issue":"Suppl 2","key":"2020050712425432000_103.10.927.6","first-page":"72","article-title":"Neonatal screening for glucose-6-phosphate dehydrogenase deficiency in Taiwan","volume":"30","author":"Chiang","year":"1999","journal-title":"Southeast Asian J Trop Med Public Health"}],"container-title":["Archives of Disease in Childhood"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/archdischild-2017-314063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T22:10:51Z","timestamp":1601071851000},"score":1,"resource":{"primary":{"URL":"https:\/\/adc.bmj.com\/lookup\/doi\/10.1136\/archdischild-2017-314063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,22]]},"references-count":6,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,9,19]]},"published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1136\/archdischild-2017-314063"],"URL":"https:\/\/doi.org\/10.1136\/archdischild-2017-314063","relation":{},"ISSN":["0003-9888","1468-2044"],"issn-type":[{"value":"0003-9888","type":"print"},{"value":"1468-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,22]]}}}