{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T05:45:43Z","timestamp":1793857543029,"version":"4.6.1"},"reference-count":59,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1136\/ard-2023-224689","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T17:26:27Z","timestamp":1711473987000},"page":"1006-1017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Characterisation of choroid plexus-infiltrating T cells reveals novel therapeutic targets in murine neuropsychiatric lupus"],"prefix":"10.1016","volume":"83","author":[{"given":"Erica","family":"Moore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushma","family":"Bharrhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9672-7746","authenticated-orcid":false,"given":"Deepak A","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Macian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3204-6068","authenticated-orcid":false,"given":"Chaim","family":"Putterman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1136\/ard-2023-224689_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/s41584-018-0156-8","article-title":"Neuropsychiatric lupus: new mechanistic insights and future treatment directions","volume":"15","author":"Schwartz","year":"2019","journal-title":"Nat Rev Rheumatol"},{"key":"10.1136\/ard-2023-224689_bib2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.autrev.2015.10.003","article-title":"A meta-analysis of serum and cerebrospinal fluid autoantibodies in neuropsychiatric systemic lupus erythematosus","volume":"15","author":"Ho","year":"2016","journal-title":"Autoimmun Rev"},{"key":"10.1136\/ard-2023-224689_bib3","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/jnnp.58.5.548","article-title":"Oligoclonal banding of IgG in CSF, blood-brain barrier function, and MRI findings in patients with sarcoidosis, systemic lupus erythematosus, and Beh\u00e7et's disease involving the nervous system","volume":"58","author":"McLean","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1136\/ard-2023-224689_bib4","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12987-020-00196-2","article-title":"Choroid plexus and the blood\u2013cerebrospinal fluid barrier in disease","volume":"17","author":"Sol\u00e1r","year":"2020","journal-title":"Fluids Barriers CNS"},{"key":"10.1136\/ard-2023-224689_bib5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/4734","article-title":"Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy","volume":"5","author":"Moalem","year":"1999","journal-title":"Nat Med"},{"key":"10.1136\/ard-2023-224689_bib6","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.biopsych.2008.07.014","article-title":"Vaccination as a novel approach for treating depressive behavior","volume":"65","author":"Lewitus","year":"2009","journal-title":"Biol Psychiatry"},{"key":"10.1136\/ard-2023-224689_bib7","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.it.2005.07.004","article-title":"The INS and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms","volume":"26","author":"Engelhardt","year":"2005","journal-title":"Trends Immunol"},{"key":"10.1136\/ard-2023-224689_bib8","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nrn.2017.39","article-title":"How and why do T cells and their derived cytokines affect the injured and healthy brain?","volume":"18","author":"Filiano","year":"2017","journal-title":"Nat Rev Neurosci"},{"key":"10.1136\/ard-2023-224689_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01066","article-title":"The choroid plexus functions as a niche for T-cell stimulation within the central nervous system","volume":"9","author":"Strominger","year":"2018","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0021-9975(08)80122-3","article-title":"Clinical neurology and brain histopathology in NZB\/NZW F1 lupus mice","volume":"102","author":"Kier","year":"1990","journal-title":"J Comp Pathol"},{"key":"10.1136\/ard-2023-224689_bib11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jneuroim.2006.06.023","article-title":"Distribution and prevalence of leukocyte phenotypes in brains of lupus-prone mice","volume":"179","author":"Ma","year":"2006","journal-title":"J Neuroimmunol"},{"key":"10.1136\/ard-2023-224689_bib12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0022-3476(75)80831-6","article-title":"The choroid plexus in CNS involvement of systemic lupus erythematosus","volume":"87","author":"Gershwin","year":"1975","journal-title":"J Pediatr"},{"key":"10.1136\/ard-2023-224689_bib13","first-page":"645","article-title":"Immunoperoxidase staining of the choroid plexus in systemic lupus erythematosus","volume":"7","author":"Boyer","year":"1980","journal-title":"J Rheumatol"},{"key":"10.1136\/ard-2023-224689_bib14","first-page":"387","article-title":"Selective involvement of the choroid plexus on cerebral magnetic resonance images: a new radiological sign in patients with systemic lupus erythematosus with neurological symptoms","volume":"28","author":"Duprez","year":"2001","journal-title":"J Rheumatol"},{"key":"10.1136\/ard-2023-224689_bib15","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1172\/jci.insight.124203","article-title":"Tertiary lymphoid structures in the choroid plexus in neuropsychiatric lupus","volume":"4","author":"Stock","year":"2019","journal-title":"JCI Insight"},{"key":"10.1136\/ard-2023-224689_bib16","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3389\/fimmu.2018.00487","article-title":"A distinct T follicular helper cell subset infiltrates the brain in murine neuropsychiatric lupus","volume":"9","author":"Jain","year":"2018","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.01476","article-title":"The T cell receptor repertoire in neuropsychiatric systemic lupus erythematosus","volume":"11","author":"Moore","year":"2020","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nri.2017.76","article-title":"Single-cell RNA sequencing to explore immune cell heterogeneity","volume":"18","author":"Papalexi","year":"2018","journal-title":"Nat Rev Immunol"},{"key":"10.1136\/ard-2023-224689_bib19","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12016-020-08813-6","article-title":"The application of single-cell RNA sequencing in studies of autoimmune diseases: a comprehensive review","volume":"60","author":"Zhao","year":"2021","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1136\/ard-2023-224689_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14049","article-title":"Massively parallel digital transcriptional profiling of single cells","volume":"8","author":"Zheng","year":"2017","journal-title":"Nat Commun"},{"key":"10.1136\/ard-2023-224689_bib21","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nbt.4096","article-title":"Integrating single-cell transcriptomic data across different conditions, technologies, and species","volume":"36","author":"Butler","year":"2018","journal-title":"Nat Biotechnol"},{"key":"10.1136\/ard-2023-224689_bib22","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-23324-4","article-title":"Interpretation of T cell states from single-cell transcriptomics data using reference atlases","volume":"12","author":"Andreatta","year":"2021","journal-title":"Nat Commun"},{"key":"10.1136\/ard-2023-224689_bib23","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-21246-9","article-title":"Inference and analysis of cell-cell communication using cellchat","volume":"12","author":"Jin","year":"2021","journal-title":"Nat Commun"},{"key":"10.1136\/ard-2023-224689_bib24","doi-asserted-by":"crossref","first-page":"47","DOI":"10.12688\/f1000research.22139.1","article-title":"scRepertoire: an R-based toolkit for single-cell immune receptor analysis","volume":"9","author":"Borcherding","year":"2020","journal-title":"F1000Res"},{"key":"10.1136\/ard-2023-224689_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.640725","article-title":"Tcrmatch: predicting T-cell receptor specificity based on sequence similarity to previously characterized receptors","volume":"12","author":"Chronister","year":"2021","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib26","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.763065","article-title":"CXCL13 neutralization attenuates neuropsychiatric manifestations in lupus-prone mice","volume":"12","author":"Huang","year":"2021","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib27","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1177\/0961203319872265","article-title":"Anti-IFNAR treatment does not reverse neuropsychiatric disease in MRL\/lpr lupus mice","volume":"28","author":"Huang","year":"2019","journal-title":"Lupus"},{"key":"10.1136\/ard-2023-224689_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.02189","article-title":"Neuropsychiatric systemic lupus erythematosus is dependent on sphingosine-1-phosphate signaling","volume":"9","author":"Mike","year":"2018","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib29","doi-asserted-by":"crossref","first-page":"3796","DOI":"10.1016\/j.csbj.2021.06.043","article-title":"Ucell: robust and scalable single-cell gene signature scoring","volume":"19","author":"Andreatta","year":"2021","journal-title":"Comput Struct Biotechnol J"},{"key":"10.1136\/ard-2023-224689_bib30","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1161\/CIRCULATIONAHA.119.041694","article-title":"Single-cell sequencing of mouse heart immune infiltrate in pressure overload-driven heart failure reveals extent of immune activation","volume":"140","author":"Martini","year":"2019","journal-title":"Circulation"},{"key":"10.1136\/ard-2023-224689_bib31","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-27232-5","article-title":"Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation","volume":"12","author":"Lee","year":"2021","journal-title":"Nat Commun"},{"key":"10.1136\/ard-2023-224689_bib32","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/s41593-019-0393-4","article-title":"A single-cell Atlas of Mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment","volume":"22","author":"Van Hove","year":"2019","journal-title":"Nat Neurosci"},{"key":"10.1136\/ard-2023-224689_bib33","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1016\/j.celrep.2018.11.003","article-title":"Single-cell transcriptomics characterizes cell types in the subventricular zone and uncovers molecular defects impairing adult neurogenesis","volume":"25","author":"Zywitza","year":"2018","journal-title":"Cell Rep"},{"key":"10.1136\/ard-2023-224689_bib34","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1172\/jci.insight.130062","article-title":"PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21","volume":"4","author":"Bocharnikov","year":"2019","journal-title":"JCI Insight"},{"key":"10.1136\/ard-2023-224689_bib35","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/imr.13069","article-title":"T peripheral helper cells in autoimmune diseases","volume":"307","author":"Marks","year":"2022","journal-title":"Immunol Rev"},{"key":"10.1136\/ard-2023-224689_bib36","doi-asserted-by":"crossref","first-page":"194","DOI":"10.3389\/fimmu.2017.00194","article-title":"CD4 CTL, a cytotoxic subset of CD4+ T cells, their differentiation and function","volume":"8","author":"Takeuchi","year":"2017","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102870","article-title":"Abnormalities of T cells in systemic lupus erythematosus: new insights in pathogenesis and therapeutic strategies","volume":"132","author":"Li","year":"2022","journal-title":"J Autoimmun"},{"key":"10.1136\/ard-2023-224689_bib38","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.156048","article-title":"Heterogeneity and clonality of kidney-infiltrating T cells in murine lupus nephritis","volume":"7","author":"Smita","year":"2022","journal-title":"JCI Insight"},{"key":"10.1136\/ard-2023-224689_bib39","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1002\/art.42252","article-title":"Choroid plexus-infiltrating T cells drive murine neuropsychiatric lupus","volume":"74","author":"Moore","year":"2022","journal-title":"Arthritis Rheumatol"},{"key":"10.1136\/ard-2023-224689_bib40","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1136\/annrheumdis-2015-207653","article-title":"Efficacy and safety of subcutaneous tabalumab in patients with systemic lupus erythematosus: results from ILLUMINATE-1, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study","volume":"75","author":"Isenberg","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard-2023-224689_bib41","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s40265-018-0872-z","article-title":"Belimumab: a review in systemic lupus erythematosus","volume":"78","author":"Blair","year":"2018","journal-title":"Drugs"},{"key":"10.1136\/ard-2023-224689_bib42","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.2147\/NDT.S114636","article-title":"The use of natalizumab for multiple sclerosis","volume":"13","author":"Brandstadter","year":"2017","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1136\/ard-2023-224689_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1058267","article-title":"Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells","volume":"14","author":"Thelen","year":"2023","journal-title":"Front Immunol"},{"key":"10.1136\/ard-2023-224689_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms9437","article-title":"Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation","volume":"6","author":"Raveney","year":"2015","journal-title":"Nat Commun"},{"key":"10.1136\/ard-2023-224689_bib45","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1152\/japplphysiol.00108.2020","article-title":"The impact of hypoxia on blood-brain, blood-CSF, and CSF-brain barriers","volume":"131","author":"Dunn","year":"2021","journal-title":"J Appl Physiol (1985)"},{"key":"10.1136\/ard-2023-224689_bib46","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s40478-020-0885-1","article-title":"Inflammation of the choroid plexus in progressive multiple sclerosis: accumulation of granulocytes and T cells","volume":"8","author":"Rodr\u00edguez-Lorenzo","year":"2020","journal-title":"Acta Neuropathol Commun"},{"key":"10.1136\/ard-2023-224689_bib47","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/s41590-020-00834-9","article-title":"Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion","volume":"22","author":"Scharping","year":"2021","journal-title":"Nat Immunol"},{"key":"10.1136\/ard-2023-224689_bib48","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/jmr.1143","article-title":"Affinity and catalytic heterogeneity and metal-dependence of polyclonal myelin basic protein-hydrolyzing IgGs from sera of patients with systemic lupus erythematosus","volume":"24","author":"Bezuglova","year":"2011","journal-title":"J Mol Recognit"},{"key":"10.1136\/ard-2023-224689_bib49","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41583-021-00525-w","article-title":"Emerging roles for CNS fibroblasts in health, injury and disease","volume":"23","author":"Dorrier","year":"2022","journal-title":"Nat Rev Neurosci"},{"key":"10.1136\/ard-2023-224689_bib50","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/s41593-020-00770-9","article-title":"CNS fibroblasts form a fibrotic scar in response to immune cell infiltration","volume":"24","author":"Dorrier","year":"2021","journal-title":"Nat Neurosci"},{"key":"10.1136\/ard-2023-224689_bib51","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1172\/JCI11717","article-title":"Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis","volume":"107","author":"Theien","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1136\/ard-2023-224689_bib52","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1164\/ajrccm.162.3.9910100","article-title":"Timing of administration of anti-VLA-4 differentiates airway hyperresponsiveness in the central and peripheral airways in mice","volume":"162","author":"Kanehiro","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1136\/ard-2023-224689_bib53","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.bbadis.2015.10.018","article-title":"Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke","volume":"1862","author":"Lopes Pinheiro","year":"2016","journal-title":"Biochim Biophys Acta"},{"key":"10.1136\/ard-2023-224689_bib54","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1365-2249.2006.03056.x","article-title":"Cerebral leucocyte infiltration in lupus-prone MRL\/MpJ-fas Lpr mice-roles of Intercellular adhesion molecule-1 and P-selectin","volume":"144","author":"James","year":"2006","journal-title":"Clin Exp Immunol"},{"key":"10.1136\/ard-2023-224689_bib55","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/207504","article-title":"The MRL\/lpr mouse strain as a model for neuropsychiatric systemic lupus erythematosus","volume":"2011","author":"Gulinello","year":"2011","journal-title":"J Biomed Biotechnol"},{"key":"10.1136\/ard-2023-224689_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2020.102490","article-title":"Are lupus animal models useful for understanding and developing new therapies for human SLE","volume":"112","author":"Moore","year":"2020","journal-title":"J Autoimmun"},{"key":"10.1136\/ard-2023-224689_bib57","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1002\/art.42080","article-title":"Aptamer-based screen of neuropsychiatric lupus cerebrospinal fluid reveals potential biomarkers that overlap with the choroid plexus transcriptome","volume":"74","author":"Vanarsa","year":"2022","journal-title":"Arthritis Rheumatol"},{"key":"10.1136\/ard-2023-224689_bib58","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev-immunol-093019-110159","article-title":"Microglia and central nervous system-associated macrophages-from origin to disease modulation","volume":"39","author":"Prinz","year":"2021","journal-title":"Annu Rev Immunol"},{"key":"10.1136\/ard-2023-224689_bib59","doi-asserted-by":"crossref","first-page":"3056","DOI":"10.1016\/j.cell.2021.04.003","article-title":"A cellular and spatial map of the choroid plexus across brain ventricles and ages","volume":"184","author":"Dani","year":"2021","journal-title":"Cell"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724000232?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724000232?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard-2023-224689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T06:00:28Z","timestamp":1736056828000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724000232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":59,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["S0003496724000232"],"URL":"https:\/\/doi.org\/10.1136\/ard-2023-224689","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterisation of choroid plexus-infiltrating T cells reveals novel therapeutic targets in murine neuropsychiatric lupus","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard-2023-224689","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2024 \u00a9 Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by Elsevier Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}