{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T15:21:28Z","timestamp":1779895288908,"version":"3.53.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1136\/ard.2006.066704","type":"journal-article","created":{"date-parts":[[2006,12,2]],"date-time":"2006-12-02T01:34:51Z","timestamp":1165023291000},"page":"646-650","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Arthritis of the large joints\u2014in particular, the knee\u2014at first presentation is predictive for a high level of radiological destruction of the small joints in rheumatoid arthritis"],"prefix":"10.1016","volume":"66","author":[{"given":"S P","family":"Linn-Rasker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A H M","family":"van der Helm-van Mil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F C","family":"Breedveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T W J","family":"Huizinga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1136\/ard.2006.066704_bib1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.rdc.2005.07.008","article-title":"Potential for altering rheumatoid arthritis outcome","volume":"31","author":"Quinn","year":"2005","journal-title":"Rheum Dis North Am"},{"key":"10.1136\/ard.2006.066704_bib2","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.rdc.2005.07.001","article-title":"The evidence for early intervention","volume":"31","author":"Quinn","year":"2005","journal-title":"Rheum Dis North Am"},{"key":"10.1136\/ard.2006.066704_bib3","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/bmj.332.7534.152","article-title":"Treatment of rheumatoid arthritis","volume":"332","author":"Emery","year":"2006","journal-title":"BMJ"},{"key":"10.1136\/ard.2006.066704_bib4","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/art.10117","article-title":"How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis","volume":"46","author":"Visser","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2006.066704_bib5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.berh.2004.08.005","article-title":"Early diagnosis of rheumatoid arthritis","volume":"19","author":"Visser","year":"2005","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib6","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1136\/bmj.313.7055.471","article-title":"A simple algorithm to predict the development of radiological erosions in patients with early rheumatoid arthritis: prospective cohort study","volume":"316","author":"Brennan","year":"1996","journal-title":"BMJ"},{"key":"10.1136\/ard.2006.066704_bib7","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/art.20006","article-title":"Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients","volume":"50","author":"Gorman","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2006.066704_bib8","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1186\/ar1767","article-title":"Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis","volume":"7","author":"Van der Helm-van Mil","year":"2005","journal-title":"Arthritis Res Ther"},{"key":"10.1136\/ard.2006.066704_bib9","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/art.20044","article-title":"Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study","volume":"50","author":"van Gaalen","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2006.066704_bib10","first-page":"231","article-title":"Predictive value of antibodies to cyclic citrullinated peptide in patients with very early inflammatory arthritis","volume":"32","author":"Raza","year":"2005","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib11","first-page":"1670","article-title":"How often is seropositive rheumatoid arthritis an erosive disease? A 17 year followup study","volume":"20","author":"Kaarela","year":"1993","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib12","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/rheumatology\/keg184","article-title":"Anti-cyclic citrullinated peptide antibodies, IgM and IgA rheumatoid factors in the diagnosis and prognosis of rheumatoid arthritis (Oxford)","volume":"42","author":"Bas","year":"2003","journal-title":"Rheumatology"},{"key":"10.1136\/ard.2006.066704_bib13","first-page":"1","article-title":"Clinical laboratory and genetic markers associated with erosions and remission in patients with early inflammatory arthritis: a prospective cohort study","volume":"7","author":"Stockman","year":"2005","journal-title":"Rheumatol Int"},{"key":"10.1136\/ard.2006.066704_bib14","first-page":"48","article-title":"Is it possible to predict radiological damage in early rheumatoid arthritis? A report on the occurrence, progression and prognostic factors of radiological erosions over the first 3 years in 866 patients from the early RA study (ERAS)","volume":"69","author":"Dixey","year":"2004","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib15","first-page":"55","article-title":"Radiological progression in established rheumatoid arthritis","volume":"69","author":"Scott","year":"2004","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib16","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/art.11445","article-title":"Prognostic markers of radiologic progression in early rheumatoid arthritis","volume":"50","author":"Goronzy","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2006.066704_bib17","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1136\/ard.2005.041376","article-title":"Radiological outcome in rheumatoid arthritis is predicted by the presence of antibodies against cyclic citrullinated peptide before and at disease onset, and by IgA-rheumatoid factor at disease onset","volume":"65","author":"Berglin","year":"2006","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.2006.066704_bib18","first-page":"100","article-title":"The Leiden Early Arthritis Clinic","volume":"21","author":"van Aken","year":"2003","journal-title":"Clin Exp Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib19","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","article-title":"The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis","volume":"31","author":"Arnett","year":"1988","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2006.066704_bib20","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1002\/art.1780241012","article-title":"Preliminary criteria for clinical remission in rheumatoid arthritis","volume":"24","author":"Pinals","year":"1981","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2006.066704_bib21","first-page":"4","article-title":"Sustained remission in a cohort of patients with rheumatoid arthritis: association with absence of IgM RF and absence of anti-CCP antibodies","volume":"2","author":"Linn-Rasker","year":"2004","journal-title":"Int J Adv Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib22","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0950-3579(96)80043-4","article-title":"Plain X-rays in rheumatoid arthritis: overview of scoring methods, their reliability and applicability","volume":"10","author":"Van der Heide","year":"1996","journal-title":"Bailliere\u2019s Clin Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib23","first-page":"261","article-title":"How to read radiographs according to the Sharp-van der Heijde method","volume":"27","author":"Van der Heide","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.2006.066704_bib24","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1136\/ard.55.3.157","article-title":"Diagnostic and prognostic characteristics of enzyme linked immunosorbent rheumatoid factor assays in rheumatoid arthritis","volume":"55","author":"Visser","year":"1996","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.2006.066704_bib25","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/j.1365-2362.1991.tb01398.x","article-title":"Relationship between local inflammation, interleukin-6 concentration and the acute phase protein response in arthritis patients","volume":"21","author":"Holt","year":"1991","journal-title":"Eur J Clin Invest"},{"key":"10.1136\/ard.2006.066704_bib26","doi-asserted-by":"crossref","first-page":"3604","DOI":"10.4049\/jimmunol.159.7.3604","article-title":"Constitutive intra-articular expression of human IL-1\u03b2 following gene-transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis","volume":"159","author":"Ghivizzani","year":"1997","journal-title":"J Immunol"},{"key":"10.1136\/ard.2006.066704_bib27","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/rheumatology\/keh201","article-title":"The role of interleukin-1 in the pathogenesis of rheumatoid arthritis","volume":"43","author":"Kay","year":"2004","journal-title":"Rheumatology"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724192977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724192977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.2006.066704","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T01:10:17Z","timestamp":1737249017000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724192977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0003496724192977"],"URL":"https:\/\/doi.org\/10.1136\/ard.2006.066704","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Arthritis of the large joints\u2014in particular, the knee\u2014at first presentation is predictive for a high level of radiological destruction of the small joints in rheumatoid arthritis","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.2006.066704","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Copyright 2007 by Annals of the Rheumatic Diseases, Published by Elsevier Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}