{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T08:38:33Z","timestamp":1793176713484,"version":"4.5.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1136\/ard.2010.145821","type":"journal-article","created":{"date-parts":[[2011,5,26]],"date-time":"2011-05-26T00:19:28Z","timestamp":1306369168000},"page":"1655-1663","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["Spontaneous resolution of acute gouty arthritis is associated with rapid induction of the anti-inflammatory factors TGF\u03b21, IL-10 and soluble TNF receptors and the intracellular cytokine negative regulators CIS and SOCS3"],"prefix":"10.1016","volume":"70","author":[{"given":"Yu-Hsuan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Chou","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ko-Jen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Han","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Chang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Youh","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Li","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1136\/ard.2010.145821_bib1","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1172\/JCI29404","article-title":"Gout: new insights into an old disease.","volume":"116","author":"Martinon","year":"2006","journal-title":"J Clin Invest"},{"issue":"Suppl 3","key":"10.1136\/ard.2010.145821_bib2","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1186\/ar562","article-title":"Interactions between leukocytes and endothelial cells in gout: lessons from a self-limiting inflammatory response.","volume":"4","author":"Haskard","year":"2002","journal-title":"Arthritis Res"},{"key":"10.1136\/ard.2010.145821_bib3","doi-asserted-by":"crossref","first-page":"6370","DOI":"10.4049\/jimmunol.177.9.6370","article-title":"Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.","volume":"177","author":"Scott","year":"2006","journal-title":"J Immunol"},{"issue":"Suppl 1","key":"10.1136\/ard.2010.145821_bib4","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1186\/ar1908","article-title":"The inflammatory process of gout and its treatment.","volume":"8","author":"Cronstein","year":"2006","journal-title":"Arthritis Res Ther"},{"key":"10.1136\/ard.2010.145821_bib5","series-title":"Rheumatology","first-page":"1891","article-title":"Crystal-related arthropathies","author":"Poor","year":"2003"},{"key":"10.1136\/ard.2010.145821_bib6","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1002\/art.1780360912","article-title":"Changes in the proteins coating monosodium urate crystals during active and subsiding inflammation. Immunogold studies of synovial fluid from patients with gout and of fluid obtained using the rat subcutaneous air pouch model.","volume":"36","author":"Ortiz-Bravo","year":"1993","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib7","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1002\/art.1780390718","article-title":"Inhibition and prevention of monosodium urate monohydrate crystal-induced acute inflammation in vivo by transforming growth factor beta1.","volume":"39","author":"Liot\u00e9","year":"1996","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/art.1780360118","article-title":"Superoxide anion production and phagocytosis of crystals by cultured endothelial cells.","volume":"36","author":"Falasca","year":"1993","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib9","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.4049\/jimmunol.138.10.3213","article-title":"Interleukin 1 (IL-1) as a mediator of crystal arthritis: stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL-1","volume":"138","author":"DiGiovine","year":"1987","journal-title":"J Immunol"},{"key":"10.1136\/ard.2010.145821_bib10","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1172\/JCI113921","article-title":"Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis.","volume":"83","author":"Guerne","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1136\/ard.2010.145821_bib11","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1002\/anr.1780321114","article-title":"Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes.","volume":"32","author":"Guerne","year":"1989","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib12","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1002\/art.1780340716","article-title":"Monocyte-derived neutrophil chemotactic factor\/interleukin-8 is a potential mediator of crystal-induced inflammation.","volume":"34","author":"Terkeltaub","year":"1991","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib13","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1002\/1529-0131(200008)43:8<1779::AID-ANR14>3.0.CO;2-2","article-title":"Noninflammatory phagocytosis of monosodium urate monohydrate crystals by mouse macrophages. Implications for the control of joint inflammation in gout.","volume":"43","author":"Yagnik","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib14","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1002\/art.20317","article-title":"Macrophage release of transforming growth factor beta1 during resolution of monosodium urate monohydrate crystal-induced inflammation.","volume":"50","author":"Yagnik","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib15","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1002\/art.10614","article-title":"Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages.","volume":"46","author":"Landis","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib16","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1172\/JCI1112","article-title":"Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine\/paracrine mechanisms involving TGF-beta, PGE2, and PAF.","volume":"101","author":"Fadok","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1136\/ard.2010.145821_bib17","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/ar1741","article-title":"Negative regulation of cytokine signaling and immune responses by SOCS proteins.","volume":"7","author":"Yoshimura","year":"2005","journal-title":"Arthritis Res Ther"},{"key":"10.1136\/ard.2010.145821_bib18","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.semcdb.2008.07.010","article-title":"SOCS regulation of the JAK\/STAT signalling pathway.","volume":"19","author":"Croker","year":"2008","journal-title":"Semin Cell Dev Biol"},{"key":"10.1136\/ard.2010.145821_bib19","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/art.1780200320","article-title":"Preliminary criteria for the classification of the acute arthritis of primary gout.","volume":"20","author":"Wallace","year":"1977","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib20","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","article-title":"Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.","volume":"29","author":"Altman","year":"1986","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib21","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","article-title":"The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.","volume":"31","author":"Arnett","year":"1988","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib22","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/art.1780270401","article-title":"Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria.","volume":"27","author":"van der Linden","year":"1984","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib23","first-page":"469","article-title":"The inflammatory reaction to sodium urate","volume":"180","author":"Seegmiller","year":"1962","journal-title":"JAMA"},{"key":"10.1136\/ard.2010.145821_bib24","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1084\/jem.20052333","article-title":"Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1.","volume":"203","author":"Kinjyo","year":"2006","journal-title":"J Exp Med"},{"key":"10.1136\/ard.2010.145821_bib25","doi-asserted-by":"crossref","first-page":"4845","DOI":"10.1073\/pnas.89.11.4845","article-title":"Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.","volume":"89","author":"Van Zee","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1136\/ard.2010.145821_bib26","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1002\/j.1460-2075.1995.tb07281.x","article-title":"A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.","volume":"14","author":"Yoshimura","year":"1995","journal-title":"EMBO J"},{"key":"10.1136\/ard.2010.145821_bib27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1146\/annurev.immunol.18.1.143","article-title":"Negative regulation of cytokine signaling pathways.","volume":"18","author":"Yasukawa","year":"2000","journal-title":"Annu Rev Immunol"},{"key":"10.1136\/ard.2010.145821_bib28","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.niox.2004.09.003","article-title":"Stimulation of inducible nitric oxide synthase by monosodium urate crystals in macrophages and expression of iNOS in gouty arthritis.","volume":"11","author":"Chen","year":"2004","journal-title":"Nitric Oxide"},{"key":"10.1136\/ard.2010.145821_bib29","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.4049\/jimmunol.165.3.1612","article-title":"Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression.","volume":"165","author":"Benkhart","year":"2000","journal-title":"J Immunol"},{"key":"10.1136\/ard.2010.145821_bib30","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1084\/jem.169.1.291","article-title":"Active and latent forms of transforming growth factor beta activity in synovial effusions.","volume":"169","author":"Fava","year":"1989","journal-title":"J Exp Med"},{"key":"10.1136\/ard.2010.145821_bib31","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1002\/art.10468","article-title":"Antiinflammatory effect of retrovirally transfected interleukin-10 on monosodium urate monohydrate crystal-induced acute inflammation in murine air pouches.","volume":"46","author":"Murakami","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib32","doi-asserted-by":"crossref","first-page":"8781","DOI":"10.1073\/pnas.87.22.8781","article-title":"Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients.","volume":"87","author":"Gatanaga","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1136\/ard.2010.145821_bib33","doi-asserted-by":"crossref","first-page":"11974","DOI":"10.1016\/S0021-9258(18)80162-4","article-title":"A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity.","volume":"264","author":"Engelmann","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1136\/ard.2010.145821_bib34","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1002\/hep.1840160322","article-title":"High concentrations of soluble tumor necrosis factor receptors in ascites.","volume":"16","author":"Andus","year":"1992","journal-title":"Hepatology"},{"key":"10.1136\/ard.2010.145821_bib35","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1002\/art.1780351008","article-title":"Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases.","volume":"35","author":"Cope","year":"1992","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib36","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1002\/art.1780360812","article-title":"Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus.","volume":"36","author":"Aderka","year":"1993","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.2010.145821_bib37","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1016\/0959-8049(93)90212-X","article-title":"Serum soluble tumour necrosis factor receptor 55 is increased in patients with haematological neoplasias and is associated with immune activation and weight loss.","volume":"29A","author":"Denz","year":"1993","journal-title":"Eur J Cancer"},{"key":"10.1136\/ard.2010.145821_bib38","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1093\/intimm\/dxq015","article-title":"Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression.","volume":"22","author":"Ripley","year":"2010","journal-title":"Int Immunol"},{"key":"10.1136\/ard.2010.145821_bib39","doi-asserted-by":"crossref","first-page":"3148","DOI":"10.1182\/blood.V89.9.3148","article-title":"CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation.","volume":"89","author":"Matsumoto","year":"1997","journal-title":"Blood"},{"key":"10.1136\/ard.2010.145821_bib40","doi-asserted-by":"crossref","first-page":"25043","DOI":"10.1074\/jbc.272.40.25043","article-title":"Tyrosine docking sites of the rat prolactin receptor required for association and activation of stat5.","volume":"272","author":"Pezet","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1136\/ard.2010.145821_bib41","doi-asserted-by":"crossref","first-page":"35553","DOI":"10.1074\/jbc.274.50.35553","article-title":"SOCS\/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms.","volume":"274","author":"Ram","year":"1999","journal-title":"J Biol Chem"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724191728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724191728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.2010.145821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T20:09:03Z","timestamp":1737230943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724191728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0003496724191728"],"URL":"https:\/\/doi.org\/10.1136\/ard.2010.145821","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spontaneous resolution of acute gouty arthritis is associated with rapid induction of the anti-inflammatory factors TGF\u03b21, IL-10 and soluble TNF receptors and the intracellular cytokine negative regulators CIS and SOCS3","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.2010.145821","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Published by Elsevier Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}